SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway BJ Willett, J Grove, OA MacLean, C Wilkie, G De Lorenzo, W Furnon, ... Nature microbiology 7 (8), 1161-1179, 2022 | 511 | 2022 |
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ... PLoS biology 19 (2), e3001091, 2021 | 195 | 2021 |
A prenylated dsRNA sensor protects against severe COVID-19 A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ... Science 374 (6567), eabj3624, 2021 | 169 | 2021 |
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism BJ Willett, J Grove, OA MacLean, C Wilkie, N Logan, GD Lorenzo, ... MedRxiv, 2022.01. 03.21268111, 2022 | 168 | 2022 |
In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2 AM Szemiel, A Merits, RJ Orton, OA MacLean, RM Pinto, A Wickenhagen, ... PLoS pathogens 17 (9), e1009929, 2021 | 141 | 2021 |
Characterization of a second open reading frame in genome segment 10 of bluetongue virus M Stewart, A Hardy, G Barry, RM Pinto, M Caporale, E Melzi, J Hughes, ... Journal of General Virology 96 (11), 3280-3293, 2015 | 128 | 2015 |
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses RM Pinto, S Bakshi, S Lytras, MK Zakaria, S Swingler, JC Worrell, ... Nature 619 (7969), 338-347, 2023 | 43 | 2023 |
COVID-19 Genomics UK (COG-UK) Consortium BJ Willett, J Grove, OA MacLean, C Wilkie, G De Lorenzo, W Furnon, ... SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry …, 2022 | 37 | 2022 |
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses V Herder, K Dee, JK Wojtus, I Epifano, D Goldfarb, C Rozario, Q Gu, ... PLoS biology 19 (12), e3001065, 2021 | 28 | 2021 |
TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway NR Choudhury, I Trus, G Heikel, M Wolczyk, J Szymanski, A Bolembach, ... Nucleic Acids Research 50 (12), 7097-7114, 2022 | 21 | 2022 |
Accessory gene products of influenza A virus RM Pinto, S Lycett, E Gaunt, P Digard Cold Spring Harbor perspectives in medicine 11 (12), a038380, 2021 | 21 | 2021 |
Cotransfer of antigen and contextual information harmonizes peripheral and lymph node conventional dendritic cell activation C Pirillo, S Al Khalidi, A Sims, R Devlin, H Zhao, R Pinto, S Jasim, ... Science immunology 8 (85), eadg8249, 2023 | 17 | 2023 |
A prenylated dsRNA sensor protects against severe COVID-19. Science 374, eabj3624 A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ... | 16 | 2021 |
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice M Varela, RM Pinto, M Caporale, IM Piras, A Taggart, F Seehusen, ... Journal of virology 90 (11), 5440-5450, 2016 | 15 | 2016 |
Effects of mutations in the effector domain of influenza A virus NS1 protein CF Pereira, HM Wise, D Kurian, RM Pinto, MJ Amorim, AC Gill, P Digard BMC research notes 11, 1-7, 2018 | 14 | 2018 |
In vitro evolution of Remdesivir resistance reveals genome plasticity of SARS-CoV-2 AM Szemiel, A Merits, RJ Orton, O MacLean, RM Pinto, A Wickenhagen, ... BioRxiv, 2021.02. 01.429199, 2021 | 13 | 2021 |
Sensitivity to BST-2 restriction correlates with Orthobunyavirus host range M Varela, IM Piras, C Mullan, X Shi, NL Tilston-Lunel, RM Pinto, A Taggart, ... Virology 509, 121-130, 2017 | 13 | 2017 |
CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy CP Sharp, BH Thompson, TJ Nash, O Diebold, RM Pinto, L Thorley, ... PLoS Pathogens 19 (5), e1011357, 2023 | 10 | 2023 |
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of the induction of IFN-mediated innate immune defences V Herder, K Dee, JK Wojtus, D Goldfarb, C Rozario, Q Gu, RF Jarrett, ... bioRxiv, 2020.12. 04.411389, 2020 | 10 | 2020 |
Zoonotic avian influenza viruses evade human BTN3A3 restriction RM Pinto, S Bakshi, S Lytras, MK Zakaria, S Swingler, JC Worrell, ... bioRxiv, 2022.06. 14.496196, 2022 | 8 | 2022 |