| Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics Y Yang, J Kitagaki, RM Dai, YC Tsai, KL Lorick, RL Ludwig, SA Pierre, ... Cancer research 67 (19), 9472-9481, 2007 | 539 | 2007 |
| Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis GP Leboucher, YC Tsai, M Yang, KC Shaw, M Zhou, TD Veenstra, ... Molecular cell 47 (4), 547-557, 2012 | 365 | 2012 |
| Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function YC Tsai, PS Fishman, NV Thakor, GA Oyler Journal of Biological Chemistry 278 (24), 22044-22055, 2003 | 357 | 2003 |
| The unfolded protein response, degradation from the endoplasmic reticulum, and cancer YC Tsai, AM Weissman Genes & cancer 1 (7), 764-778, 2010 | 339 | 2010 |
| The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site B Chen, J Mariano, YC Tsai, AH Chan, M Cohen, AM Weissman Proceedings of the National Academy of Sciences 103 (2), 341-346, 2006 | 257 | 2006 |
| Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5 S Lee, YC Tsai, R Mattera, WJ Smith, MS Kostelansky, AM Weissman, ... Nature structural & molecular biology 13 (3), 264-271, 2006 | 239 | 2006 |
| Differences in the tumor microenvironment between African-American and European-American breast cancer patients DN Martin, BJ Boersma, M Yi, M Reimers, TM Howe, HG Yfantis, YC Tsai, ... PloS one 4 (2), e4531, 2009 | 238 | 2009 |
| The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation YC Tsai, A Mendoza, JM Mariano, M Zhou, Z Kostova, B Chen, T Veenstra, ... Nature medicine 13 (12), 1504-1509, 2007 | 225 | 2007 |
| Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation Z Kostova, YC Tsai, AM Weissman Seminars in cell & developmental biology 18 (6), 770-779, 2007 | 205 | 2007 |
| Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78 R Das, J Mariano, YC Tsai, RC Kalathur, Z Kostova, J Li, SG Tarasov, ... Molecular cell 34 (6), 674-685, 2009 | 180 | 2009 |
| The Rab5 guanine nucleotide exchange factor Rabex-5 binds ubiquitin (Ub) and functions as a Ub ligase through an atypical Ub-interacting motif and a zinc finger domain R Mattera, YC Tsai, AM Weissman, JS Bonifacino Journal of Biological Chemistry 281 (10), 6874-6883, 2006 | 143 | 2006 |
| Dissecting the diverse functions of the metastasis suppressor CD82/KAI1 YC Tsai, AM Weissman FEBS letters 585 (20), 3166-3173, 2011 | 118 | 2011 |
| Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system YC Tsai, R Maditz, C Kuo, PS Fishman, CB Shoemaker, GA Oyler, ... Proceedings of the National Academy of Sciences 107 (38), 16554-16559, 2010 | 98 | 2010 |
| Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system YC Tsai, GS Leichner, MMP Pearce, GL Wilson, RJH Wojcikiewicz, ... Molecular biology of the cell 23 (23), 4484-4494, 2012 | 87 | 2012 |
| Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis KL Marie, A Sassano, HH Yang, AM Michalowski, HT Michael, T Guo, ... Nature Communications 11 (1), 333, 2020 | 74 | 2020 |
| Anterior thalamic mediation of experimental seizures: selective EEG spectral coherence MA Mirski, YC Tsai, LA Rossell, NV Thakor, DL Sherman Epilepsia 44 (3), 355-365, 2003 | 67 | 2003 |
| Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum A Shmueli, YC Tsai, M Yang, MA Braun, AM Weissman Biochemical and biophysical research communications 390 (3), 758-762, 2009 | 66 | 2009 |
| BCL-xL-dependent light scattering by apoptotic cells NN Boustany, YC Tsai, B Pfister, WM Joiner, GA Oyler, NV Thakor Biophysical journal 87 (6), 4163-4171, 2004 | 61 | 2004 |
| Protein engineering in the ubiquitin system: tools for discovery and beyond B Zhao, YC Tsai, B Jin, B Wang, Y Wang, H Zhou, T Carpenter, ... Pharmacological Reviews 72 (2), 380-413, 2020 | 57 | 2020 |
| RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene A Brauweiler, KL Lorick, JP Lee, YC Tsai, D Chan, AM Weissman, ... Oncogene 26 (16), 2263-2271, 2007 | 55 | 2007 |
George OylerPrecision Brain MD llc, Johns Hopkins University在 jhu.edu 的电子邮件经过验证
