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Johann Matschke
Johann Matschke
Group Leader, Institute of Cell Biology (Cancer Research)
在 uk-essen.de 的电子邮件经过验证 - 首页
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Oxidative stress: the lowest common denominator of multiple diseases
V Matschke, C Theiss, J Matschke
Neural regeneration research 14 (2), 238-241, 2019
792019
The mitochondrial citrate carrier (SLC25A1) sustains redox homeostasis and mitochondrial metabolism supporting radioresistance of cancer cells with tolerance to cycling severe …
J Hlouschek, C Hansel, V Jendrossek, J Matschke
Frontiers in oncology 8, 170, 2018
642018
Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia
J Hlouschek, V Ritter, F Wirsdörfer, D Klein, V Jendrossek, J Matschke
Cancer letters 439, 24-38, 2018
572018
Targeted inhibition of glutamine-dependent glutathione metabolism overcomes death resistance induced by chronic cycling hypoxia
J Matschke, H Riffkin, D Klein, R Handrick, L Lüdemann, E Metzen, ...
Antioxidants & redox signaling 25 (2), 89-107, 2016
572016
Proton irradiation increases the necessity for homologous recombination repair along with the indispensability of non-homologous end joining
K Szymonowicz, A Krysztofiak, J van der Linden, A Kern, S Deycmar, ...
Cells 9 (4), 889, 2020
452020
Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction
Y Henning, US Blind, S Larafa, J Matschke, J Fandrey
Cell death & disease 13 (7), 662, 2022
392022
Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia
J Matschke, E Wiebeck, S Hurst, J Rudner, V Jendrossek
Radiation Oncology 11, 1-12, 2016
352016
A new twist in protein kinase B/Akt signaling: role of altered cancer cell metabolism in Akt-mediated therapy resistance
I Götting, V Jendrossek, J Matschke
International Journal of Molecular Sciences 21 (22), 8563, 2020
252020
The natural plant product rottlerin activates Kv7. 1/KCNE1 channels
V Matschke, I Piccini, J Schubert, E Wrobel, F Lang, J Matschke, ...
Cellular Physiology and Biochemistry 40 (6), 1549-1558, 2016
232016
Oncometabolites and the response to radiotherapy
K Xiang, V Jendrossek, J Matschke
Radiation Oncology 15 (1), 197, 2020
202020
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma
B Shannan, J Matschke, H Chauvistré, F Vogel, D Klein, F Meier, ...
European Journal of Cancer 109, 137-153, 2019
192019
Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown
A Krysztofiak, K Szymonowicz, J Hlouschek, K Xiang, C Waterkamp, ...
IScience 24 (11), 2021
162021
Adaptation to chronic-cycling hypoxia renders cancer cells resistant to MTH1-inhibitor treatment which can be counteracted by glutathione depletion
C Hansel, J Hlouschek, K Xiang, M Melnikova, J Thomale, T Helleday, ...
Cells 10 (11), 3040, 2021
102021
Increased ROS-dependent fission of mitochondria causes abnormal morphology of the cell powerhouses in a murine model of amyotrophic lateral sclerosis
J Stein, B Walkenfort, H Cihankaya, M Hasenberg, V Bader, ...
Oxidative Medicine and Cellular Longevity 2021, 2021
102021
Metabolic reprograming of antioxidant defense: a precision medicine perspective for radiotherapy of lung cancer?
J Matschke, S Larafa, V Jendrossek
Biochemical Society Transactions 49 (3), 1265-1277, 2021
72021
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
M Junghans, F John, H Cihankaya, D Schliebs, KF Winklhofer, V Bader, ...
Frontiers in Cellular Neuroscience 16, 963169, 2022
42022
A sequential targeting strategy interrupts AKT-driven subclone-mediated progression in glioblastoma
S Kebir, V Ullrich, P Berger, C Dobersalske, S Langer, L Rauschenbach, ...
Clinical Cancer Research 29 (2), 488-500, 2023
32023
Accumulation of oncometabolite D-2-Hydroxyglutarate by SLC25A1 inhibition: A metabolic strategy for induction of HR-ness and radiosensitivity
K Xiang, C Kalthoff, C Münch, V Jendrossek, J Matschke
Cell Death & Disease 13 (7), 641, 2022
32022
Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation
I Goetting, S Larafa, K Eul, M Kunin, B Jakob, J Matschke, V Jendrossek
Frontiers in Oncology 12, 920017, 2022
22022
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state …
M Dellin, I Rohrbeck, P Asrani, JA Schreiber, N Ritter, F Glorius, ...
Biological Chemistry 404 (4), 241-254, 2023
12023
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