Oxidative stress: the lowest common denominator of multiple diseases V Matschke, C Theiss, J Matschke Neural regeneration research 14 (2), 238-241, 2019 | 79 | 2019 |
The mitochondrial citrate carrier (SLC25A1) sustains redox homeostasis and mitochondrial metabolism supporting radioresistance of cancer cells with tolerance to cycling severe … J Hlouschek, C Hansel, V Jendrossek, J Matschke Frontiers in oncology 8, 170, 2018 | 64 | 2018 |
Targeting SLC25A10 alleviates improved antioxidant capacity and associated radioresistance of cancer cells induced by chronic-cycling hypoxia J Hlouschek, V Ritter, F Wirsdörfer, D Klein, V Jendrossek, J Matschke Cancer letters 439, 24-38, 2018 | 57 | 2018 |
Targeted inhibition of glutamine-dependent glutathione metabolism overcomes death resistance induced by chronic cycling hypoxia J Matschke, H Riffkin, D Klein, R Handrick, L Lüdemann, E Metzen, ... Antioxidants & redox signaling 25 (2), 89-107, 2016 | 57 | 2016 |
Proton irradiation increases the necessity for homologous recombination repair along with the indispensability of non-homologous end joining K Szymonowicz, A Krysztofiak, J van der Linden, A Kern, S Deycmar, ... Cells 9 (4), 889, 2020 | 45 | 2020 |
Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction Y Henning, US Blind, S Larafa, J Matschke, J Fandrey Cell death & disease 13 (7), 662, 2022 | 39 | 2022 |
Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia J Matschke, E Wiebeck, S Hurst, J Rudner, V Jendrossek Radiation Oncology 11, 1-12, 2016 | 35 | 2016 |
A new twist in protein kinase B/Akt signaling: role of altered cancer cell metabolism in Akt-mediated therapy resistance I Götting, V Jendrossek, J Matschke International Journal of Molecular Sciences 21 (22), 8563, 2020 | 25 | 2020 |
The natural plant product rottlerin activates Kv7. 1/KCNE1 channels V Matschke, I Piccini, J Schubert, E Wrobel, F Lang, J Matschke, ... Cellular Physiology and Biochemistry 40 (6), 1549-1558, 2016 | 23 | 2016 |
Oncometabolites and the response to radiotherapy K Xiang, V Jendrossek, J Matschke Radiation Oncology 15 (1), 197, 2020 | 20 | 2020 |
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma B Shannan, J Matschke, H Chauvistré, F Vogel, D Klein, F Meier, ... European Journal of Cancer 109, 137-153, 2019 | 19 | 2019 |
Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown A Krysztofiak, K Szymonowicz, J Hlouschek, K Xiang, C Waterkamp, ... IScience 24 (11), 2021 | 16 | 2021 |
Adaptation to chronic-cycling hypoxia renders cancer cells resistant to MTH1-inhibitor treatment which can be counteracted by glutathione depletion C Hansel, J Hlouschek, K Xiang, M Melnikova, J Thomale, T Helleday, ... Cells 10 (11), 3040, 2021 | 10 | 2021 |
Increased ROS-dependent fission of mitochondria causes abnormal morphology of the cell powerhouses in a murine model of amyotrophic lateral sclerosis J Stein, B Walkenfort, H Cihankaya, M Hasenberg, V Bader, ... Oxidative Medicine and Cellular Longevity 2021, 2021 | 10 | 2021 |
Metabolic reprograming of antioxidant defense: a precision medicine perspective for radiotherapy of lung cancer? J Matschke, S Larafa, V Jendrossek Biochemical Society Transactions 49 (3), 1265-1277, 2021 | 7 | 2021 |
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro M Junghans, F John, H Cihankaya, D Schliebs, KF Winklhofer, V Bader, ... Frontiers in Cellular Neuroscience 16, 963169, 2022 | 4 | 2022 |
A sequential targeting strategy interrupts AKT-driven subclone-mediated progression in glioblastoma S Kebir, V Ullrich, P Berger, C Dobersalske, S Langer, L Rauschenbach, ... Clinical Cancer Research 29 (2), 488-500, 2023 | 3 | 2023 |
Accumulation of oncometabolite D-2-Hydroxyglutarate by SLC25A1 inhibition: A metabolic strategy for induction of HR-ness and radiosensitivity K Xiang, C Kalthoff, C Münch, V Jendrossek, J Matschke Cell Death & Disease 13 (7), 641, 2022 | 3 | 2022 |
Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation I Goetting, S Larafa, K Eul, M Kunin, B Jakob, J Matschke, V Jendrossek Frontiers in Oncology 12, 920017, 2022 | 2 | 2022 |
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state … M Dellin, I Rohrbeck, P Asrani, JA Schreiber, N Ritter, F Glorius, ... Biological Chemistry 404 (4), 241-254, 2023 | 1 | 2023 |