| Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations J Champer, R Reeves, SY Oh, C Liu, J Liu, AG Clark, PW Messer PLoS genetics 13 (7), e1006796, 2017 | 295 | 2017 |
| Reducing resistance allele formation in CRISPR gene drive J Champer, J Liu, SY Oh, R Reeves, A Luthra, N Oakes, AG Clark, ... Proceedings of the National Academy of Sciences 115 (21), 5522-5527, 2018 | 233 | 2018 |
| Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer D Cui Zhou, RG Jayasinghe, S Chen, JM Herndon, MD Iglesia, P Navale, ... Nature genetics 54 (9), 1390-1405, 2022 | 105 | 2022 |
| A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population J Champer, E Yang, E Lee, J Liu, AG Clark, PW Messer Proceedings of the National Academy of Sciences 117 (39), 24377-24383, 2020 | 100 | 2020 |
| Population dynamics of underdominance gene drive systems in continuous space J Champer, J Zhao, SE Champer, J Liu, PW Messer ACS synthetic biology 9 (4), 779-792, 2020 | 50 | 2020 |
| Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response AZ Wang, JA Bowman-Kirigin, R Desai, LI Kang, PR Patel, B Patel, ... Genome medicine 14 (1), 49, 2022 | 48 | 2022 |
| CRISPR gene drive efficiency and resistance rate is highly heritable with no common genetic loci of large effect J Champer, Z Wen, A Luthra, R Reeves, J Chung, C Liu, YL Lee, J Liu, ... Genetics 212 (1), 333-341, 2019 | 44* | 2019 |
| Maximum likelihood estimation of fitness components in experimental evolution J Liu, J Champer, AM Langmüller, C Liu, J Chung, R Reeves, A Luthra, ... Genetics 211 (3), 1005-1017, 2019 | 31 | 2019 |
| Epigenetic regulation during cancer transitions across 11 tumour types NV Terekhanova, A Karpova, WW Liang, A Strzalkowski, S Chen, Y Li, ... Nature 623 (7986), 432-441, 2023 | 25 | 2023 |
| Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations AM Langmüller, J Champer, S Lapinska, L Xie, M Metzloff, SE Champer, ... Elife 11, e71809, 2022 | 17 | 2022 |
| Multi-scale signaling and tumor evolution in high-grade gliomas J Liu, S Cao, KJ Imbach, MA Gritsenko, TSM Lih, JE Kyle, TM Yaron-Barir, ... Cancer Cell 42 (7), 1217-1238. e19, 2024 | | 2024 |
