关注
Kai Connie Wu
Kai Connie Wu
Senior Scientist, Janssen R&D
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Beneficial role of Nrf2 in regulating NADPH generation and consumption
KC Wu, JY Cui, CD Klaassen
Toxicological Sciences 123 (2), 590-600, 2011
3752011
Effect of graded Nrf2 activation on phase-I and-II drug metabolizing enzymes and transporters in mouse liver
KC Wu, JY Cui, CD Klaassen
PloS one 7 (7), e39006, 2012
1652012
Nrf2 activation prevents cadmium-induced acute liver injury
KC Wu, JJ Liu, CD Klaassen
Toxicology and applied pharmacology 263 (1), 14-20, 2012
1612012
NRF2 Protection against Liver Injury Produced by Various Hepatotoxicants
J Liu, KC Wu, YF Lu, E Ekuase, CD Klaassen
Oxidative medicine and cellular longevity 2013, 2013
1542013
Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation
KC Wu, J Liu, CD Klaassen
Toxicology and applied pharmacology 262 (3), 321-329, 2012
1472012
Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice
YKJ Zhang, KC Wu, CD Klaassen
PloS one 8 (3), e59122, 2013
1072013
Nrf2 deficiency improves glucose tolerance in mice fed a high-fat diet
YKJ Zhang, KC Wu, J Liu, CD Klaassen
Toxicology and applied pharmacology 264 (3), 305-314, 2012
972012
Screening of Natural Compounds as Activators of the Keap1-Nrf2 Pathway
KC Wu, PR McDonald, J Liu, CD Klaassen
Planta medica 80 (01), 97-104, 2014
942014
Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice
J Liu, YF Lu, Y Zhang, KC Wu, F Fan, CD Klaassen
Toxicology and applied pharmacology 272 (3), 816-824, 2013
512013
Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway
KC Wu, PR McDonald, JJ Liu, R Chaguturu, CD Klaassen
Public Library of Science 7 (10), e44686, 2012
502012
Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor
J Rooney, K Oshida, N Vasani, B Vallanat, N Ryan, BN Chorley, X Wang, ...
PloS one 13 (8), e0200004, 2018
472018
Nrf2 protects against diquat-induced liver and lung injury
KC Wu, Y Zhang, CD Klaassen
Free Radical Research 46 (10), 1220-1229, 2012
462012
Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2
YF Lu, J Liu, KC Wu, CD Klaassen
Toxicology letters 232 (1), 326-332, 2015
412015
Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice
YF Lu, J Liu, KC Wu, Q Qu, F Fan, CD Klaassen
PLOS ONE 9 (3), e93013, 2014
382014
Structure-based design of potent, selective, and orally bioavailable VPS34 kinase inhibitors
DX Hu, S Patel, H Chen, S Wang, ST Staben, YN Dimitrova, ...
Journal of Medicinal Chemistry 65 (17), 11500-11512, 2021
142021
Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy
K Thapa, KC Wu, A Sarma, EM Grund, A Szeto, AJ Mendez, S Gesta, ...
Cell & bioscience 8 (1), 1-13, 2018
142018
RNA-Seq provides new insights on the relative mRNA abundance of antioxidant components during mouse liver development
KC Wu, JY Cui, J Liu, H Lu, X Zhong, CD Klaassen
Free Radical Biology and Medicine 134, 335-342, 2019
102019
Tissue distribution, hormonal regulation, ontogeny, diurnal expression, and induction of mouse cystine transporters Slc3a1 and Slc7a9
KC Wu, SA Reisman, CD Klaassen
Free radical research 54 (7), 525-534, 2020
62020
Assessment of skin toxicity in an in vitro reconstituted human epidermis model using deep learning
F Hu, SF Santagostino, DM Danilenko, M Tseng, J Brumm, P Zehnder, ...
The American Journal of Pathology 192 (4), 687-700, 2022
52022
Predicting Human Infection Risk: Do Rodent Host Resistance Models Add Value?
KC Wu, Y Zhong, J Maher
Toxicological Sciences 170 (2), 260-272, 2019
22019
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