| NAD+ cleavage activity by animal and plant TIR domains in cell death pathways S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ... Science 365 (6455), 793-799, 2019 | 426 | 2019 |
| SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration MD Figley, W Gu, JD Nanson, Y Shi, Y Sasaki, K Cunnea, AK Malde, X Jia, ... Neuron 109 (7), 1118-1136. e11, 2021 | 215 | 2021 |
| Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules Y Shi, PS Kerry, JD Nanson, T Bosanac, Y Sasaki, R Krauss, FK Saikot, ... Molecular cell 82 (9), 1643-1659. e10, 2022 | 79 | 2022 |
| Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling MK Manik, Y Shi, S Li, MA Zaydman, N Damaraju, S Eastman, TG Smith, ... Science 377 (6614), eadc8969, 2022 | 78 | 2022 |
| Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... Elife 10, e72823, 2021 | 36 | 2021 |
| Structural evolution of TIR-domain signalosomes S Nimma, W Gu, N Maruta, Y Li, M Pan, FK Saikot, BYJ Lim, ... Frontiers in Immunology 12, 784484, 2021 | 36 | 2021 |
| A novel NAD signaling mechanism in axon degeneration and its relationship to innate immunity EL Hopkins, W Gu, B Kobe, MP Coleman Frontiers in Molecular Biosciences 8, 703532, 2021 | 35 | 2021 |
| Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection Y Sasaki, J Zhu, Y Shi, W Gu, B Kobe, T Ve, A DiAntonio, J Milbrandt Experimental Neurology 345, 113842, 2021 | 25 | 2021 |
| Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity A Loreto, C Angeletti, W Gu, A Osborne, B Nieuwenhuis, J Gilley, ... BioRxiv, 2020.09. 18.304261, 2020 | 16 | 2020 |
| Sarm1-dependent axon degeneration: Nucleotide signaling, neurodegenerative disorders, toxicity, and therapeutic opportunities HY McGuinness, W Gu, Y Shi, B Kobe, T Ve The Neuroscientist 30 (4), 473-492, 2024 | 11 | 2024 |
| Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling MK Manik, Y Shi, S Li, MA Zaydman, N Damaraju, S Eastman, TG Smith, ... BioRxiv, 2022.05. 07.491051, 2022 | 9 | 2022 |
| Crystal structure of the Toll/interleukin‐1 receptor (TIR) domain of IL‐1R10 provides structural insights into TIR domain signalling S Nimma, W Gu, MK Manik, T Ve, JD Nanson, B Kobe FEBS letters 596 (7), 886-897, 2022 | 7 | 2022 |
| Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing W Gu, Z Luo, C Vonrhein, X Jia, T Ve, JD Nanson, B Kobe Acta Crystallographica Section F: Structural Biology Communications 77 (10 …, 2021 | 4 | 2021 |
| Structural characterization of TIR-domain signalosomes through a combination of structural biology approaches A Bhatt, BP Mishra, W Gu, M Sorbello, H Xu, T Ve, B Kobe IUCrJ 11 (5), 2024 | | 2024 |
| Structural characterization of macro domain–containing Thoeris antiphage defense systems Y Shi, V Masic, T Mosaiab, P Rajaratman, L Hartley-Tassell, M Sorbello, ... Science Advances 10 (26), eadn3310, 2024 | | 2024 |
| Development of 3D-ED/MicroED facility at the University of Queensland KSA Arachchige, N Koifman, W Gu, B Kobe, JK Clegg, H Xu, R Wepf Acta Crystallographica Section A Foundations and Advances 79 (a2), C975-C975, 2023 | | 2023 |
| Structural basis for activation and inhibition of the pro-neurodegenerative NADase SARM1 Y Shi, J Nanson, W Gu, V Masic, T Mosaiab, M Landsberg, B Kobe, T Ve Acta Crystallographica Section A Foundations and Advances 79 (a2), C843-C843, 2023 | | 2023 |
| Structural basis of an anti-cancer biological warhead bound to its target CDCP1 for the diagnosis and treatment of epithelial cancers K Kwah, W Gu, KSA Arachchige, Y He, M Landsberg, B Kobe, J Hooper Acta Crystallographica Section A Foundations and Advances 79 (a2), C1177-C1177, 2023 | | 2023 |
| Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology B Kobe, JD Nanson, MK Manik, S Li, W Gu, M Pan, Y Li, TW Muusse, ... Acta Crystallographica Section A Foundations and Advances 79 (a2), C246-C246, 2023 | | 2023 |
| Characterisation of Axundead, a novel downstream regulator of Wallerian degeneration HY McGuinness, AL Rosell, W Gu, J Nanson, T Ve, B Kobe Acta Crystallographica Section A Foundations and Advances 79 (a2), C854-C854, 2023 | | 2023 |
