An atlas of human glycosylation pathways enables display of the human glycome by gene engineered cells Y Narimatsu, HJ Joshi, R Nason, J Van Coillie, R Karlsson, L Sun, Z Ye, ... Molecular cell 75 (2), 394-407. e5, 2019 | 220 | 2019 |
The GAGOme: a cell-based library of displayed glycosaminoglycans YH Chen, Y Narimatsu, TM Clausen, C Gomes, R Karlsson, C Steentoft, ... Nature methods 15 (11), 881-888, 2018 | 129 | 2018 |
Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations JA Tree, JE Turnbull, KR Buttigieg, MJ Elmore, N Coombes, J Hogwood, ... British Journal of Pharmacology 178 (3), 626-635, 2021 | 102 | 2021 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 83 | 2022 |
Evidence of a Putative Glycosaminoglycan Binding Site on the Glycosylated SARS-CoV-2 Spike Protein N-terminal domain ZP Schuurs, E Hammond, S Elli, TR Rudd, CJ Mycroft-West, MA Lima, ... Computational and Structural Biotechnology Journal, 2021 | 46 | 2021 |
The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models SP Davies, CJ Mycroft-West, I Pagani, HJ Hill, YH Chen, R Karlsson, ... Frontiers in Pharmacology 12, 1755, 2021 | 45 | 2021 |
The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor M Sarwar, AS Syed Khaja, M Aleskandarany, R Karlsson, M Althobiti, ... Oncogene 38 (3), 375-389, 2019 | 42 | 2019 |
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates R Karlsson, P Chopra, A Joshi, Z Yang, SY Vakhrushev, TM Clausen, ... Science advances 7 (52), eabl6026, 2021 | 35 | 2021 |
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors AL Gray, R Karlsson, ARE Roberts, AJL Ridley, N Pun, B Khan, ... Cell reports 42 (1), 2023 | 27 | 2023 |
Cryogenic Infrared Spectroscopy Reveals Structural Modularity in the Vibrational Fingerprints of Heparan Sulfate Diastereomers M Lettow, M Grabarics, K Greis, E Mucha, DA Thomas, P Chopra, ... Analytical Chemistry 92 (15), 10228-10232, 2020 | 24 | 2020 |
Identification of global inhibitors of cellular glycosylation DM Sørensen, C Büll, TD Madsen, E Lira-Navarrete, TM Clausen, ... Nature Communications 14 (1), 948, 2023 | 11 | 2023 |
Establishment of Prostate Tumor Growth and Metastasis Is Supported by Bone Marrow Cells and Is Mediated by PIP5K1α Lipid Kinase R Karlsson, P Larsson, R Miftakhova, AS Syed Khaja, M Sarwar, ... Cancers 12 (9), 2719, 2020 | 9 | 2020 |
Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans AJL Ridley, Y Ou, R Karlsson, N Pun, HL Birchenough, IZ Mulholland, ... Science Signaling 16 (810), eadf2537, 2023 | 7 | 2023 |
Engineering mammalian cells to produce plant-specific N-glycosylation on proteins JS Larsen, RTG Karlsson, W Tian, MA Schulz, A Matthes, H Clausen, ... Glycobiology 30 (8), 528-538, 2020 | 7 | 2020 |
Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 infection I Bagdonaite, IN Marinova, AM Rudjord-Levann, EMH Pallesen, ... Nature Communications 14 (1), 7000, 2023 | 2 | 2023 |
FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer PF Larsson, R Karlsson, M Sarwar, R Miftakhova, T Wang, AS Syed Khaja, ... Molecular Oncology 16 (13), 2496-2517, 2022 | 2 | 2022 |
Structure and function of Semaphorin-5A glycosaminoglycan interactions GN Nagy, XF Zhao, R Karlsson, K Wang, R Duman, K Harlos, K El Omari, ... Nature Communications 15 (1), 2723, 2024 | 1 | 2024 |
Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate EE Vidal-Calvo, A Martin-Salazar, S Choudhary, R Dagil, SSR Raghavan, ... Nature Communications 15 (1), 7553, 2024 | | 2024 |