Intrinsic protein disorder in oncogenic KRAS signaling R Nussinov, H Jang, CJ Tsai, TJ Liao, S Li, D Fushman, J Zhang Cellular and Molecular Life Sciences 74, 3245-3261, 2017 | 52 | 2017 |
Autoinhibition in Ras effectors Raf, PI3Kα, and RASSF5: a comprehensive review underscoring the challenges in pharmacological intervention R Nussinov, M Zhang, CJ Tsai, TJ Liao, D Fushman, H Jang Biophysical reviews 10 (5), 1263-1282, 2018 | 42 | 2018 |
High-affinity interactions of the nSH3/cSH3 domains of Grb2 with the C-terminal proline-rich domain of SOS1 TJ Liao, H Jang, R Nussinov, D Fushman Journal of the American Chemical Society 142 (7), 3401-3411, 2020 | 38 | 2020 |
RASSF5: An MST activator and tumor suppressor in vivo but opposite in vitro TJ Liao, CJ Tsai, H Jang, D Fushman, R Nussinov Current opinion in structural biology 41, 217-224, 2016 | 36 | 2016 |
Allosteric KRas4B can modulate SOS1 fast and slow Ras activation cycles TJ Liao, H Jang, D Fushman, R Nussinov Biophysical Journal 115 (4), 629-641, 2018 | 34 | 2018 |
The dynamic mechanism of RASSF5 and MST kinase activation by Ras TJ Liao, H Jang, CJ Tsai, D Fushman, R Nussinov Physical Chemistry Chemical Physics 19 (9), 6470-6480, 2017 | 30 | 2017 |
SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations TJ Liao, H Jang, D Fushman, R Nussinov The Journal of Chemical Physics 153 (4), 2020 | 20 | 2020 |
Machine learning to identify interaction of single-nucleotide polymorphisms as a risk factor for chronic drug-induced liver injury R Moore, K Ashby, TJ Liao, M Chen International Journal of Environmental Research and Public Health 18 (20), 10603, 2021 | 7 | 2021 |
Whole exome sequencing reveals genetic variants in HLA class II genes associated with transplant-free survival of indeterminate acute liver failure TJ Liao, B Pan, H Hong, P Hayashi, JA Rule, D Ganger, WM Lee, ... Clinical and translational gastroenterology, 10.14309, 2022 | 3 | 2022 |
Medical device report analyses from MAUDE: Device and patient outcomes, adverse events, and sex-based differential effects TJ Liao, L Crosby, K Cross, M Chen, R Elespuru Regulatory Toxicology and Pharmacology 149, 105591, 2024 | 2 | 2024 |
Computational Modeling for the prediction of hepatotoxicity caused by drugs and chemicals M Chen, J Liu, TJ Liao, K Ashby, Y Wu, L Wu, W Tong, H Hong Machine learning and deep learning in computational toxicology, 541-561, 2023 | 2 | 2023 |
Drug interaction with UDP-Glucuronosyltransferase (UGT) enzymes is a predictor of drug-induced liver injury AOO Olubamiwa, TJ Liao, J Zhao, P Dehanne, C Noban, Y Angin, ... Hepatology, 10.1097, 2024 | 1 | 2024 |
QSAR modeling for predicting drug-induced liver injury TJ Liao, J Zhao, M Chen QSAR in Safety Evaluation and Risk Assessment, 295-300, 2023 | | 2023 |
DILIrank dataset for QSAR modeling of drug-induced liver injury M Chen, TJ Liao, D Li, B Ning, H Hong, W Tong QSAR in Safety Evaluation and Risk Assessment, 235-243, 2023 | | 2023 |
Deciphering How EGFR-GRB2-SOS1 Complex Regulates KRas4B Activation and Leads to Hippo Signaling Through RASSF5 TJ Liao University of Maryland, College Park, 2021 | | 2021 |