| Aicardi-Goutieres syndrome is caused by IFIH1 mutations H Oda, K Nakagawa, J Abe, T Awaya, M Funabiki, A Hijikata, ... The American Journal of Human Genetics 95 (1), 121-125, 2014 | 228 | 2014 |
| High-resolution crystal structure of M-protease: phylogeny aided analysis of the high-alkaline adaptation mechanism. T Shirai, A Suzuki, T Yamane, T Ashida, T Kobayashi, J Hitomi, S Ito Protein engineering 10 (6), 627-634, 1997 | 135 | 1997 |
| Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment H Ohashi, K Watashi, W Saso, K Shionoya, S Iwanami, T Hirokawa, ... Iscience 24 (4), 2021 | 123 | 2021 |
| Identification of a High‐Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell–Based Phenotype Dissection Y Kawasaki, H Oda, J Ito, A Niwa, T Tanaka, A Hijikata, R Seki, ... Arthritis & rheumatology 69 (2), 447-459, 2017 | 119 | 2017 |
| Enzymatic properties, crystallization, and deduced amino acid sequence of an alkaline endoglucanase from Bacillus circulans Y Hakamada, K Endo, S Takizawa, T Kobayashi, T Shirai, T Yamane, S Ito Biochimica et Biophysica Acta (BBA)-General Subjects 1570 (3), 174-180, 2002 | 114 | 2002 |
| Crystal structure of alkaline cellulase K: insight into the alkaline adaptation of an industrial enzyme T Shirai, H Ishida, J Noda, T Yamane, K Ozaki, Y Hakamada, S Ito Journal of molecular biology 310 (5), 1079-1087, 2001 | 103 | 2001 |
| The influence of PRNP polymorphisms on human prion disease susceptibility: an update A Kobayashi, K Teruya, Y Matsuura, T Shirai, Y Nakamura, M Yamada, ... Acta neuropathologica 130, 159-170, 2015 | 91 | 2015 |
| Mechanism of replication machinery assembly as revealed by the DNA ligase–PCNA–DNA complex architecture K Mayanagi, S Kiyonari, M Saito, T Shirai, Y Ishino, K Morikawa Proceedings of the National Academy of Sciences 106 (12), 4647-4652, 2009 | 88 | 2009 |
| Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea S Ishino, Y Nishi, S Oda, T Uemori, T Sagara, N Takatsu, T Yamagami, ... Nucleic acids research 44 (7), 2977-2986, 2016 | 73 | 2016 |
| Crystal structure of GH13 α‐glucosidase GSJ from one of the deepest sea bacteria T Shirai, VS Hung, K Morinaka, T Kobayashi, S Ito Proteins: Structure, Function, and Bioinformatics 73 (1), 126-133, 2008 | 71 | 2008 |
| Multidrug treatment with nelfinavir and cepharanthine against COVID-19 H Ohashi, K Watashi, W Saso, K Shionoya, S Iwanami, T Hirokawa, ... BioRxiv, 2020.04. 14.039925, 2020 | 69 | 2020 |
| Structural basis of the 3′‐end recognition of a leading strand in stalled replication forks by PriA K Sasaki, T Ose, N Okamoto, K Maenaka, T Tanaka, H Masai, M Saito, ... The EMBO Journal 26 (10), 2584-2593, 2007 | 64 | 2007 |
| Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex K Mayanagi, S Kiyonari, H Nishida, M Saito, D Kohda, Y Ishino, T Shirai, ... Proceedings of the National Academy of Sciences 108 (5), 1845-1849, 2011 | 61 | 2011 |
| Structure of rhamnose-binding lectin CSL3: unique pseudo-tetrameric architecture of a pattern recognition protein T Shirai, Y Watanabe, M Lee, T Ogawa, K Muramoto Journal of Molecular Biology 391 (2), 390-403, 2009 | 61 | 2009 |
| An empirical approach for structure‐based prediction of carbohydrate‐binding sites on proteins C Shionyu‐Mitsuyama, T Shirai, H Ishida, T Yamane Protein Engineering 16 (7), 467-478, 2003 | 60 | 2003 |
| High-resolution structure of the conger eel galectin, congerin I, in lactose-liganded and ligand-free forms: emergence of a new structure class by accelerated evolution T Shirai, C Mitsuyama, Y Niwa, Y Matsui, H Hotta, T Yamane, H Kamiya, ... Structure 7 (10), 1223-1233, 1999 | 60 | 1999 |
| Protein anatomy: functional roles of barnase module. H Yanagawa, K Yoshida, C Torigoe, JS Park, K Sato, T Shirai, M Go Journal of Biological Chemistry 268 (8), 5861-5865, 1993 | 57 | 1993 |
| Structure of the EndoMS-DNA complex as mismatch restriction endonuclease S Nakae, A Hijikata, T Tsuji, K Yonezawa, K Kouyama, K Mayanagi, ... Structure 24 (11), 1960-1971, 2016 | 52 | 2016 |
| Curcumin derivatives verify the essentiality of ROS upregulation in tumor suppression I Nakamae, T Morimoto, H Shima, M Shionyu, H Fujiki, N Yoneda-Kato, ... Molecules 24 (22), 4067, 2019 | 46 | 2019 |
| Pentagamavunon-1 (PGV-1) inhibits ROS metabolic enzymes and suppresses tumor cell growth by inducing M phase (prometaphase) arrest and cell senescence B Lestari, I Nakamae, N Yoneda-Kato, T Morimoto, S Kanaya, ... Scientific Reports 9 (1), 14867, 2019 | 46 | 2019 |
Atsushi HijikataTokyo University of Pharmacy and Life Sciences在 toyaku.ac.jp 的电子邮件经过验证
