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Ayat Zagzoog
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In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa
A Zagzoog, KA Mohamed, HJJ Kim, ED Kim, CS Frank, T Black, ...
Scientific Reports 10 (1), 20405, 2020
1342020
Application of fluorine-and nitrogen-walk approaches: defining the structural and functional diversity of 2-phenylindole class of cannabinoid 1 receptor positive allosteric …
S Garai, PM Kulkarni, PC Schaffer, LM Leo, AL Brandt, A Zagzoog, ...
Journal of medicinal chemistry 63 (2), 542-568, 2019
502019
Dissociable changes in spike and wave discharges following exposure to injected cannabinoids and smoked cannabis in Genetic Absence Epilepsy Rats from Strasbourg
AJ Roebuck, Q Greba, TJ Onofrychuk, DL McElroy, TM Sandini, ...
European Journal of Neuroscience 55 (4), 1063-1078, 2022
272022
Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor
A Zagzoog, AL Brandt, T Black, ED Kim, R Burkart, M Patel, Z Jin, ...
Scientific Reports 11 (1), 10611, 2021
252021
Discovery of a biased allosteric modulator for cannabinoid 1 receptor: preclinical anti-glaucoma efficacy
S Garai, LM Leo, AM Szczesniak, DP Hurst, PC Schaffer, A Zagzoog, ...
Journal of Medicinal Chemistry 64 (12), 8104-8126, 2021
232021
The endocannabinoid system and synthetic cannabinoids in preclinical models of seizure and epilepsy
AM Smolyakova, A Zagzoog, AL Brandt, T Black, K Mohamed, ...
Journal of Clinical Neurophysiology 37 (1), 15-27, 2020
162020
Indomethacin enhances type 1 cannabinoid receptor signaling
RB Laprairie, KA Mohamed, A Zagzoog, MEM Kelly, LA Stevenson, ...
Frontiers in Molecular Neuroscience 12, 257, 2019
132019
Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules
A Zagzoog, A Cabecinha, H Abramovici, RB Laprairie
Frontiers in Pharmacology 13, 956030, 2022
122022
Impact of the mouse estrus cycle on cannabinoid receptor agonist‐induced molecular and behavioral outcomes
HJJ Kim, A Zagzoog, T Black, SL Baccetto, UC Ezeaka, RB Laprairie
Pharmacology research & perspectives 10 (3), e00950, 2022
102022
The effects of acute Cannabis smoke or Δ9-THC injections on the trial-unique, nonmatching-to-location and five-choice serial reaction time tasks in male Long-Evans rats
IL Barnard, TJ Onofrychuk, TM Sandini, DL McElroy, A Zagzoog, ...
Neurobiology of learning and memory 192, 107624, 2022
82022
Characterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure
T Black, SL Baccetto, IL Barnard, E Finch, DL McElroy, FVL Austin-Scott, ...
Scientific Reports 13 (1), 21070, 2023
72023
Dual cannabinoid and orexin regulation of anhedonic behaviour caused by prolonged restraint stress
HJJ Kim, A Zagzoog, C Ceni, R Ferrisi, N Janz, RB Laprairie
Brain Sciences 13 (2), 314, 2023
62023
In vivo Evidence for Brain Region-Specific Molecular Interactions Between Cannabinoid and Orexin Receptors
HJJ Kim, A Zagzoog, AM Smolyakova, UC Ezeaka, MJ Benko, T Holt, ...
Frontiers in Neuroscience 15, 790546, 2021
62021
Molecular and cellular mechanisms underlying brain region-specific endocannabinoid system modulation by estradiol across the rodent estrus cycle
HJJ Kim, A Zagzoog, T Black, SL Baccetto, RB Laprairie
Progress in Molecular Biology and Translational Science 195, 27-45, 2023
22023
Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593
AL Brandt, S Garai, A Zagzoog, DP Hurst, LA Stevenson, RG Pertwee, ...
Frontiers in Pharmacology 13, 919605, 2022
12022
Sex-specific differences in rotarod performance and type 1 cannabinoid receptor levels in a rat model of traumatic brain injury treated with Δ9-tetrahydrocannabinol
T Black, A Zagoog, AJ Roebuck, Q Greba, JP Neary, JG Howland, ...
bioRxiv, 2022.04. 11.487790, 2022
12022
The Intoxication Equivalency of 11-Hydroxy-Δ9-tetrahydrocannabinol (11-OH-THC) Relative to Δ9-tetrahydrocannabinol (THC)
A Zagzoog, K Halter, AM Jones, N Bannatyne, J Cline, A Wilcox, ...
Journal of Pharmacology and Experimental Therapeutics, 2024
2024
Novel pharmacology of cannabidivarin, tetrahydrocannabivarin, cannabigerol, and cannabichromene in vitro and in vivo
R Laprairie, K Mohamed, D Kim, A Zagzoog
BRITISH JOURNAL OF PHARMACOLOGY 177 (11), 2626-2627, 2020
2020
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