Targeting the PI3K pathway and DNA damage response as a therapeutic strategy in ovarian cancer TT Huang, EJ Lampert, C Coots, JM Lee Cancer treatment reviews 86, 102021, 2020 | 111 | 2020 |
Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis AM Wang, TT Huang, KW Hsu, KH Huang, WL Fang, MH Yang, SS Lo, ... Oncotarget 5 (13), 5002, 2014 | 87 | 2014 |
Combination of palbociclib with enzalutamide shows in vitro activity in RB proficient and androgen receptor positive triple negative breast cancer cells CY Liu, KY Lau, CC Hsu, JL Chen, CH Lee, TT Huang, YT Chen, ... PLoS One 12 (12), e0189007, 2017 | 66 | 2017 |
Treatment for the endocrine resistant breast cancer: current options and future perspectives CY Liu, CY Wu, K Petrossian, TT Huang, LM Tseng, S Chen The Journal of steroid biochemistry and molecular biology 172, 166-175, 2017 | 60 | 2017 |
Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression KW Hsu, WL Fang, KH Huang, TT Huang, HC Lee, RH Hsieh, CW Chi, ... Oncotarget 7 (25), 38036, 2016 | 56 | 2016 |
Downregulation of tumor suppressor MBP-1 by microRNA-363 in gastric carcinogenesis KW Hsu, AM Wang, YH Ping, KH Huang, TT Huang, HC Lee, SS Lo, ... Carcinogenesis 35 (1), 208-217, 2014 | 56 | 2014 |
ER stress‐related ATF 6 upregulates CIP 2A and contributes to poor prognosis of colon cancer CY Liu, CC Hsu, TT Huang, CH Lee, JL Chen, SH Yang, JK Jiang, ... Molecular oncology 12 (10), 1706-1717, 2018 | 52 | 2018 |
Cell cycle checkpoints and beyond: Exploiting the ATR/CHK1/WEE1 pathway for the treatment of PARP inhibitor–resistant cancer N Gupta, TT Huang, S Horibata, JM Lee Pharmacological research 178, 106162, 2022 | 49 | 2022 |
Alteration of SHP-1/p-STAT3 signaling: a potential target for anticancer therapy TT Huang, JC Su, CY Liu, CW Shiau, KF Chen International Journal of Molecular Sciences 18 (6), 1234, 2017 | 49 | 2017 |
The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis TT Huang, YH Ping, AM Wang, CC Ke, WL Fang, KH Huang, HC Lee, ... Oncotarget 6 (20), 18012, 2015 | 48 | 2015 |
miR-151-3p targets TWIST1 to repress migration of human breast cancer cells TC Yeh, TT Huang, TS Yeh, YR Chen, KW Hsu, PH Yin, HC Lee, ... PloS one 11 (12), e0168171, 2016 | 47 | 2016 |
Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression CY Liu, TT Huang, YT Chen, JL Chen, PY Chu, CT Huang, WL Wang, ... EBioMedicine 40, 263-275, 2019 | 44 | 2019 |
EGFR-independent Elk1/CIP2A signalling mediates apoptotic effect of an erlotinib derivative TD52 in triple-negative breast cancer cells CY Liu, TT Huang, CT Huang, MH Hu, DS Wang, WL Wang, WC Tsai, ... European journal of cancer 72, 112-123, 2017 | 39 | 2017 |
Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression TT Huang, LM Tseng, JL Chen, PY Chu, CH Lee, CT Huang, WL Wang, ... EBioMedicine 54, 2020 | 38 | 2020 |
The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells CY Liu, TT Huang, PY Chu, CT Huang, CH Lee, WL Wang, KY Lau, ... Experimental & molecular medicine 49 (8), e366-e366, 2017 | 37 | 2017 |
Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer J Nair, TT Huang, J Murai, B Haynes, PS Steeg, Y Pommier, JM Lee Oncogene 39 (33), 5520-5535, 2020 | 35 | 2020 |
Sorafenib analogue SC‐60 induces apoptosis through the SHP‐1/STAT 3 pathway and enhances docetaxel cytotoxicity in triple‐negative breast cancer cells CY Liu, JC Su, TT Huang, PY Chu, CT Huang, WL Wang, CH Lee, KY Lau, ... Molecular oncology 11 (3), 266-279, 2017 | 34 | 2017 |
Mevalonate pathway enzyme HMGCS1 contributes to gastric cancer progression IH Wang, TT Huang, JL Chen, LW Chu, YH Ping, KW Hsu, KH Huang, ... Cancers 12 (5), 1088, 2020 | 31 | 2020 |
Varlitinib downregulates HER/ERK signaling and induces apoptosis in triple negative breast cancer cells CY Liu, PY Chu, CT Huang, JL Chen, HP Yang, WL Wang, KY Lau, ... Cancers 11 (1), 105, 2019 | 26 | 2019 |
MicroRNA‑23a/27a/24‑2 cluster promotes gastric cancer cell proliferation synergistically K Hua, YT Chen, CF Chen, YS Tang, TT Huang, YC Lin, TS Yeh, ... Oncology letters 16 (2), 2319-2325, 2018 | 26 | 2018 |