A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 350 | 2017 |
Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status L Piccio, Y Deming, JL Del-Águila, L Ghezzi, DM Holtzman, AM Fagan, ... Acta neuropathologica 131, 925-933, 2016 | 336 | 2016 |
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 226 | 2019 |
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers Y Deming, Z Li, M Kapoor, O Harari, JL Del-Aguila, K Black, D Carrell, ... Acta neuropathologica 133 (5), 839-856, 2017 | 220 | 2017 |
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease M Ewers, N Franzmeier, M Suárez-Calvet, E Morenas-Rodriguez, ... Science translational medicine 11 (507), eaav6221, 2019 | 219 | 2019 |
Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology M Suárez-Calvet, E Morenas-Rodríguez, G Kleinberger, K Schlepckow, ... Molecular neurodegeneration 14, 1-14, 2019 | 204 | 2019 |
Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms C Cruchaga, JL Del-Aguila, B Saef, K Black, MV Fernandez, J Budde, ... Alzheimer's & Dementia 14 (2), 205-214, 2018 | 141* | 2018 |
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation M Ewers, G Biechele, M Suárez‐Calvet, C Sacher, T Blume, ... EMBO molecular medicine 12 (9), e12308, 2020 | 93 | 2020 |
Sex-specific genetic predictors of Alzheimer’s disease biomarkers Y Deming, L Dumitrescu, LL Barnes, M Thambisetty, B Kunkle, KA Gifford, ... Acta neuropathologica 136, 857-872, 2018 | 92 | 2018 |
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM 2, neurodegeneration and cognitive decline M Suárez‐Calvet, A Capell, MÁ Araque Caballero, E Morenas‐Rodríguez, ... EMBO molecular medicine 10 (12), e9712, 2018 | 84 | 2018 |
Sex differences in the genetic predictors of Alzheimer’s pathology L Dumitrescu, LL Barnes, M Thambisetty, G Beecham, B Kunkle, WS Bush, ... Brain 142 (9), 2581-2589, 2019 | 73 | 2019 |
A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin Y Deming, J Xia, Y Cai, J Lord, P Holmans, S Bertelsen, D Holtzman, ... Neurobiology of aging 37, 208. e1-208. e9, 2016 | 64 | 2016 |
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion Z Li, FHG Farias, U Dube, JL Del-Aguila, KA Mihindukulasuriya, ... Acta neuropathologica 139 (1), 45-61, 2020 | 62 | 2020 |
Assessment of the genetic architecture of Alzheimer’s disease risk in rate of memory decline JL Del-Aguila, MV Fernández, S Schindler, L Ibanez, Y Deming, S Ma, ... Journal of Alzheimer's Disease 62 (2), 745-756, 2018 | 62 | 2018 |
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations DJ Panyard, KM Kim, BF Darst, YK Deming, X Zhong, Y Wu, H Kang, ... Communications biology 4 (1), 63, 2021 | 52 | 2021 |
African Americans have differences in CSF soluble TREM2 and associated genetic variants SE Schindler, C Cruchaga, A Joseph, L McCue, FHG Farias, CH Wilkins, ... Neurology: Genetics 7 (2), e571, 2021 | 39 | 2021 |
Reversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppression KM Rodgers, YK Deming, FM Bercum, SY Chumachenko, JL Wieseler, ... Journal of neurotrauma 31 (5), 487-497, 2014 | 36 | 2014 |
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease MV Fernandez, JH Kim, JP Budde, K Black, A Medvedeva, B Saef, ... PLoS genetics 13 (11), e1007045, 2017 | 32 | 2017 |
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits Y Deming, J Xia, Y Cai, J Lord, JL Del-Aguila, MV Fernandez, D Carrell, ... Scientific Reports 6 (1), 18092, 2016 | 31 | 2016 |
Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans JL Del-Aguila, MV Fernández, J Jimenez, K Black, S Ma, Y Deming, ... Alzheimer's research & therapy 7, 1-4, 2015 | 31 | 2015 |