| Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection KL Conway, P Kuballa, JH Song, KK Patel, AB Castoreno, OH Yilmaz, ... Gastroenterology 145 (6), 1347-1357, 2013 | 270 | 2013 |
| Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics SY Kuo, AB Castoreno, LN Aldrich, KG Lassen, G Goel, V Dančík, ... Proceedings of the National Academy of Sciences 112 (31), E4281-E4287, 2015 | 72 | 2015 |
| The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells B Khor, JD Gagnon, G Goel, MI Roche, KL Conway, K Tran, LN Aldrich, ... Elife 4, e05920, 2015 | 66 | 2015 |
| Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules SY Shaw, K Tran, AB Castoreno, JM Peloquin, KG Lassen, B Khor, ... ACS chemical biology 8 (12), 2724-2733, 2013 | 65 | 2013 |
| Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity I Pavlinov, EM Gerlach, LN Aldrich Organic & Biomolecular Chemistry 17 (7), 1608-1623, 2019 | 58 | 2019 |
| Discovery of a small-molecule probe for V-ATPase function LN Aldrich, SY Kuo, AB Castoreno, G Goel, P Kuballa, MG Rees, ... Journal of the American chemical society 137 (16), 5563-5568, 2015 | 51 | 2015 |
| Beclin 1–ATG14L protein–protein interaction inhibitor selectively inhibits autophagy through disruption of VPS34 complex I I Pavlinov, M Salkovski, LN Aldrich Journal of the American Chemical Society 142 (18), 8174-8182, 2020 | 48 | 2020 |
| Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs LN Aldrich, SL Stoops, BC Crews, LJ Marnett, CW Lindsley Bioorganic & medicinal chemistry letters 20 (17), 5207-5211, 2010 | 48 | 2010 |
| Autophagy and post-ischemic conditioning in retinal ischemia B Mathew, M Chennakesavalu, M Sharma, LA Torres, CR Stelman, ... Autophagy 17 (6), 1479-1499, 2021 | 47 | 2021 |
| Evaluation of the Biosynthetic Proposal for the Synthesis of Marineosins A and B LN Aldrich, ES Dawson, CW Lindsley Organic Letters 12 (5), 1048-1051, 2010 | 44 | 2010 |
| Phyllanthusmin derivatives induce apoptosis and reduce tumor burden in high-grade serous ovarian cancer by late-stage autophagy inhibition AN Young, D Herrera, AC Huntsman, MA Korkmaz, DD Lantvit, ... Molecular cancer therapeutics 17 (10), 2123-2135, 2018 | 34 | 2018 |
| Towards the total synthesis of marineosin A: construction of the macrocyclic pyrrole and an advanced, functionalized spiroaminal model LN Aldrich, CB Berry, BS Bates, LC Konkol, M So, CW Lindsley European journal of organic chemistry 2013 (20), 4215-4218, 2013 | 30 | 2013 |
| Discovery of anticancer agents of diverse natural origin LN Aldrich, JE Burdette, E Carcache de Blanco, CC Coss, AS Eustaquio, ... Journal of natural products 85 (3), 702-719, 2022 | 28 | 2022 |
| Systematic diversity-oriented synthesis of reduced flavones from γ-pyrones to probe biological performance diversity EM Gerlach, MA Korkmaz, I Pavlinov, Q Gao, LN Aldrich ACS Chemical Biology 14 (7), 1536-1545, 2019 | 24 | 2019 |
| MAOS protocols for the general synthesis and lead optimization of 3, 6-disubstituted-[1, 2, 4] triazolo [4, 3-b] pyridazines LN Aldrich, EP Lebois, LM Lewis, NT Nalywajko, CM Niswender, ... Tetrahedron letters 50 (2), 212-215, 2009 | 22 | 2009 |
| Spiroaminal model systems of the marineosins with final step pyrrole incorporation JD Panarese, LC Konkol, CB Berry, BS Bates, LN Aldrich, CW Lindsley Tetrahedron letters 54 (18), 2231-2234, 2013 | 21 | 2013 |
| PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer A Salvi, AN Young, AC Huntsman, MR Pergande, MA Korkmaz, ... Cell death & disease 13 (1), 45, 2022 | 18 | 2022 |
| Microwave‐Assisted, Asymmetric Synthesis of 3‐Amino‐2, 3‐Dihydrobenzofuran Flavonoid Derivatives from Chalcones TR Helgren, LL Xu, D Sotelo, YR Mehta, MA Korkmaz, I Pavlinov, ... Chemistry–A European Journal 24 (18), 4509-4514, 2018 | 16 | 2018 |
| Carcache de Blanco LN Aldrich, JE Burdette Coss, C. C, 702-719, 2022 | 14 | 2022 |
| Multiple Chemical Features Impact Biological Performance Diversity of a Highly Active Natural Product‐Inspired Library RS Hippman, I Pavlinov, Q Gao, MK Mavlyanova, EM Gerlach, LN Aldrich ChemBioChem 21 (21), 3137-3145, 2020 | 10 | 2020 |
