An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms HY Zou, Q Li, JH Lee, ME Arango, SR McDonnell, S Yamazaki, ... Cancer research 67 (9), 4408-4417, 2007 | 895 | 2007 |
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma JG Christensen, HY Zou, ME Arango, Q Li, JH Lee, SR McDonnell, ... Molecular cancer therapeutics 6 (12), 3314-3322, 2007 | 778 | 2007 |
Rat Muc4 (sialomucin complex) reduces binding of anti‐ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance SA Price‐Schiavi, S Jepson, P Li, M Arango, PS Rudland, L Yee, ... International journal of cancer 99 (6), 783-791, 2002 | 275 | 2002 |
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1 A Blasina, J Hallin, E Chen, ME Arango, E Kraynov, J Register, S Grant, ... Molecular cancer therapeutics 7 (8), 2394-2404, 2008 | 249 | 2008 |
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27kip, but does not activate mitogen-activated … S Jepson, M Komatsu, B Haq, ME Arango, D Huang, CAC Carraway, ... Oncogene 21 (49), 7524-7532, 2002 | 168 | 2002 |
Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor M Komatsu, S Jepson, ME Arango, CA Carothers Carraway, KL Carraway Oncogene 20 (4), 461-470, 2001 | 167 | 2001 |
Muc4/sialomucin complex, the intramembrane Er6B2 ligand, in cancer and epithelia: to protect and to survive KL Carraway, A Perez, N Idris, S Jepson, M Arango, M Komatsu, B Haq, ... Academic Press 71, 149-185, 2002 | 148 | 2002 |
Sensitivity of selected human tumor models to PF-04217903, a novel selective c-Met kinase inhibitor HY Zou, Q Li, JH Lee, ME Arango, K Burgess, M Qiu, LD Engstrom, ... Molecular cancer therapeutics 11 (4), 1036-1047, 2012 | 88 | 2012 |
PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity CC Zhang, Z Yan, Q Zhang, K Kuszpit, K Zasadny, M Qiu, CL Painter, ... Clinical Cancer Research 16 (21), 5177-5188, 2010 | 88 | 2010 |
PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts C Zhang, Z Yan, CL Painter, Q Zhang, E Chen, ME Arango, K Kuszpit, ... Clinical Cancer Research 15 (14), 4630-4640, 2009 | 71 | 2009 |
Advancing bioluminescence imaging technology for the evaluation of anticancer agents in the MDA-MB-435-HAL-Luc mammary fat pad and subrenal capsule tumor models C Zhang, Z Yan, ME Arango, CL Painter, K Anderes Clinical Cancer Research 15 (1), 238-246, 2009 | 58 | 2009 |
Production and localization of Muc4/sialomucin complex and its receptor tyrosine kinase ErbB2 in the rat lacrimal gland ME Arango, P Li, M Komatsu, C Montes, CAC Carraway, KL Carraway Investigative ophthalmology & visual science 42 (12), 2749-2756, 2001 | 53 | 2001 |
Synthesis and secretion of Muc4/sialomucin complex: implication of intracellular proteolysis M Komatsu, ME Arango, KL Carraway Biochemical Journal 368 (1), 41-48, 2002 | 46 | 2002 |
Differential 18F-FDG and 3′-deoxy-3′-18F-fluorothymidine PET responses to pharmacologic inhibition of the c-MET receptor in preclinical tumor models C Cullinane, DS Dorow, S Jackson, B Solomon, E Bogatyreva, D Binns, ... Journal of Nuclear Medicine 52 (8), 1261-1267, 2011 | 39 | 2011 |
An ErbB2-Muc4 complex in rat ocular surface epithelia JS Swan, ME Arango, CAC Carraway, KL Carraway Current eye research 24 (5), 397-402, 2002 | 21 | 2002 |
Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy C Zhang, K Lundgren, Z Yan, ME Arango, S Price, A Huber, J Higgins, ... Molecular cancer therapeutics 7 (4), 818-828, 2008 | 17 | 2008 |
Expression and localization of immunoreactive-sialomucin complex (Muc4) in salivary glands P Li, ME Arango, RE Perez, CA Reis, EL Bonfante, D Weed, KL Carraway Tissue and Cell 33 (1), 111-118, 2001 | 17 | 2001 |
PF-04217903, a novel selective c-Met kinase inhibitor with potent antitumor and anti-angiogenic properties in vitro and in vivo H Zou, Q Li, L Joseph, M Arango, K Burgess, S Yamazaki, M Parker, J Cui, ... Cancer Research 68 (9_Supplement), 4841-4841, 2008 | 9 | 2008 |
PF-00477736 an inhibitor of Chk1 enhances the antitumor activity of docetaxel indicating a role for Chk1 in the mitotic spindle checkpoint. M Hallin, C Zhang, Z Yan, M Arango, E Chen, E Kraynov, K Anderes Cancer Research 67 (9_Supplement), 4373-4373, 2007 | 5 | 2007 |
Muc4\sialomucin Complex, A Specific Intramembrane Modulator of ERBB2/HER2/NEU, Potentiates Primary Tumor Growth and Suppresses Apoptosis in A Xenotransplanted Melanoma CC Carraway, M Komatsu, S Jepson, M Arango, K Carraway The Scientific World Journal 1, 149-149, 2001 | 2 | 2001 |