| The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler GL Pardo-Andreu, Y Nuñez-Figueredo, VG Tudella, O Cuesta-Rubio, ... Mitochondrion 11 (2), 255-263, 2011 | 68 | 2011 |
| The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications GL Pardo-Andreu, Y Nuñez-Figueredo, VG Tudella, O Cuesta-Rubio, ... Toxicology and applied pharmacology 253 (3), 282-289, 2011 | 61 | 2011 |
| A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo Y Nunez-Figueredo, J Ramírez-Sánchez, G Hansel, ENS Pires, N Merino, ... Neuropharmacology 85, 517-527, 2014 | 57 | 2014 |
| Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment Y Nunez-Figueredo, GL Pardo-Andreu, J Ramírez-Sánchez, ... Brain research bulletin 109, 68-76, 2014 | 45 | 2014 |
| JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro Y Nuñez-Figueredo, J Ramírez-Sánchez, R Delgado-Hernández, ... European Journal of Pharmacology 726, 57-65, 2014 | 45 | 2014 |
| Mitochondrial involvement in memory impairment induced by scopolamine in rats M Wong-Guerra, J Jiménez-Martin, GL Pardo-Andreu, ... Neurological research 39 (7), 649-659, 2017 | 41 | 2017 |
| Clusianone, a naturally occurring nemorosone regioisomer, uncouples rat liver mitochondria and induces HepG2 cell death FHZ Reis, GL Pardo-Andreu, Y Nuñez-Figueredo, O Cuesta-Rubio, ... Chemico-biological interactions 212, 20-29, 2014 | 40 | 2014 |
| Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway J Ramírez-Sánchez, ENS Pires, Y Nuñez-Figueredo, GL Pardo-Andreu, ... Neurochemistry international 90, 215-223, 2015 | 39 | 2015 |
| Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine–dihydropyridine hybrid molecule YN Figueredo, EO Rodríguez, YV Reyes, CC Domínguez, AL Parra, ... Neurological research 35 (8), 804-812, 2013 | 33 | 2013 |
| JM-20 treatment after MCAO reduced astrocyte reactivity and neuronal death on peri-infarct regions of the rat brain J Ramírez-Sánchez, ENS Pires, A Meneghetti, G Hansel, ... Molecular neurobiology 56, 502-512, 2019 | 27 | 2019 |
| The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain Y Nuñez-Figueredo, GLP Andreu, SO Loureiro, M Ganzella, ... Neurochemistry international 81, 41-47, 2015 | 26 | 2015 |
| A strong protective action of guttiferone-A, a naturally occurring prenylated benzophenone, against iron-induced neuronal cell damage YN Figueredo, L García-Pupo, OC Rubio, RD Hernández, Z Naal, C Curti, ... Journal of pharmacological sciences 116 (1), 36-46, 2011 | 26 | 2011 |
| The cytotoxic effects of brown Cuban propolis depend on the nemorosone content and may be mediated by mitochondrial uncoupling GLP Andreu, FHZ Reis, FM Dalalio, YN Figueredo, OC Rubio, ... Chemico-Biological Interactions 228, 28-34, 2015 | 25 | 2015 |
| JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment M Wong-Guerra, J Jiménez-Martin, LA Fonseca-Fonseca, ... Neurological research 41 (5), 385-398, 2019 | 23 | 2019 |
| JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease LA Fonseca-Fonseca, M Wong-Guerra, J Ramírez-Sánchez, ... Neuroscience letters 690, 29-35, 2019 | 18 | 2019 |
| Amburana cearensis seed extract protects brain mitochondria from oxidative stress and cerebellar cells from excitotoxicity induced by glutamate ÉPL Pereira, CS Souza, J Amparo, RS Ferreira, Y Nuñez-Figueredo, ... Journal of Ethnopharmacology 209, 157-166, 2017 | 17 | 2017 |
| Efecto antiinflamatorio preclínico del polvo seco de Caléndula officinalis YN FIGUEREDO, CM ALARCÓN, SA FERNÁNDEZ, AM CERNUDA Latin American Journal of Pharmacy 26 (4), 548-52, 2007 | 17 | 2007 |
| JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats M Wong-Guerra, Y Montano-Peguero, J Ramírez-Sánchez, ... Neurotoxicology 87, 70-85, 2021 | 16 | 2021 |
| Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources FDA da Silva, PA Nogara, E Ochoa-Rodriguez, Y Nuñez-Figueredo, ... Biochimie 168, 297-306, 2020 | 16 | 2020 |
| Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices RS Ferreira, J Teles-Souza, C dos Santos Souza, ÉPL Pereira, ... Molecular Biology Reports 48, 1475-1483, 2021 | 15 | 2021 |
