| Molecular dynamics simulations in drug discovery and pharmaceutical development OMH Salo-Ahen, I Alanko, R Bhadane, AMJJ Bonvin, RV Honorato, ... Processes 9 (1), 71, 2020 | 268 | 2020 |
| Cyclohexene nucleic acids (CeNA): serum stable oligonucleotides that activate RNase H and increase duplex stability with complementary RNA J Wang, B Verbeure, I Luyten, E Lescrinier, M Froeyen, C Hendrix, ... Journal of the American Chemical Society 122 (36), 8595-8602, 2000 | 201 | 2000 |
| The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase J Jordens, V Janssens, S Longin, I Stevens, E Martens, G Bultynck, ... Journal of Biological Chemistry 281 (10), 6349-6357, 2006 | 151 | 2006 |
| Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump I Vandecaetsbeek, M Trekels, M De Maeyer, H Ceulemans, E Lescrinier, ... Proceedings of the National Academy of Sciences 106 (44), 18533-18538, 2009 | 104 | 2009 |
| Synthesis and conformational study of 3-hydroxy-4-(hydroxymethyl)-1-cyclohexanyl purines and pyrimidines Y Maurinsh, J Schraml, H De Winter, N Blaton, O Peeters, E Lescrinier, ... The Journal of Organic Chemistry 62 (9), 2861-2871, 1997 | 99 | 1997 |
| A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics J Masschelein, W Mattheus, LJ Gao, P Moons, R Van Houdt, ... PLoS One 8 (1), e54143, 2013 | 89 | 2013 |
| Synthesis and evaluation of 5-substituted 2′-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis M Kögler, B Vanderhoydonck, S De Jonghe, J Rozenski, K Van Belle, ... Journal of medicinal chemistry 54 (13), 4847-4862, 2011 | 89 | 2011 |
| Solution structure of a HNA–RNA hybrid E Lescrinier, R Esnouf, J Schraml, R Busson, HA Heus, CW Hilbers, ... Chemistry & biology 7 (9), 719-731, 2000 | 89 | 2000 |
| Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication BA Desimmie, M Humbert, E Lescrinier, J Hendrix, S Vets, R Gijsbers, ... Molecular Therapy 20 (11), 2064-2075, 2012 | 78 | 2012 |
| RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA) B Verbeure, E Lescrinier, J Wang, P Herdewijn Nucleic acids research 29 (24), 4941-4947, 2001 | 74 | 2001 |
| Difference in conformational diversity between nucleic acids with a six‐membered ‘sugar’unit and natural ‘furanose’nucleic acids E Lescrinier, M Froeyen, P Herdewijn Nucleic acids research 31 (12), 2975-2989, 2003 | 72 | 2003 |
| Synthesis and pairing properties of oligonucleotides containing 3‐hydroxy‐4‐hydroxymethyl‐1‐cyclohexanyl nucleosides Y Maurinsh, H Rosemeyer, R Esnouf, A Medvedovici, J Wang, ... Chemistry–A European Journal 5 (7), 2139-2150, 1999 | 69 | 1999 |
| Molecular dynamics simulation to investigate differences in minor groove hydration of HNA/RNA hybrids as compared to HNA/DNA complexes HD Winter, E Lescrinier, AV Aerschot, P Herdewijn Journal of the American Chemical Society 120 (22), 5381-5394, 1998 | 59 | 1998 |
| Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase S Dumbre, A Derouaux, E Lescrinier, A Piette, B Joris, M Terrak, ... Journal of the American Chemical Society 134 (22), 9343-9351, 2012 | 58 | 2012 |
| Structural characterization and biological evaluation of small interfering RNAs containing cyclohexenyl nucleosides K Nauwelaerts, M Fisher, M Froeyen, E Lescrinier, A Van Aerschot, D Xu, ... Journal of the American Chemical Society 129 (30), 9340-9348, 2007 | 55 | 2007 |
| Curing cats with feline infectious peritonitis with an oral multi-component drug containing GS-441524 D Krentz, K Zenger, M Alberer, S Felten, M Bergmann, R Dorsch, ... Viruses 13 (11), 2228, 2021 | 52 | 2021 |
| Base− Base Interactions in the Minor Groove of Double-Stranded DNA T Wu, K Nauwelaerts, A Van Aerschot, M Froeyen, E Lescrinier, ... The Journal of Organic Chemistry 71 (15), 5423-5431, 2006 | 45 | 2006 |
| DNA‐Binding Ligands from Peptide Libraries Containing Unnatural Amino Acids T Lescrinier, C Hendrix, L Kerremans, J Rozenski, A Link, B Samyn, ... Chemistry–A European Journal 4 (3), 425-433, 1998 | 45 | 1998 |
| Discovery of fructans in Archaea O Kırtel, E Lescrinier, W Van den Ende, ET Öner Carbohydrate polymers 220, 149-156, 2019 | 43 | 2019 |
| Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish Y Zhang, M Vanmeert, A Siekierska, A Ny, J John, G Callewaert, ... Scientific Reports 7 (1), 7195, 2017 | 42 | 2017 |
