Chromatin potential identified by shared single-cell profiling of RNA and chromatin S Ma, B Zhang, LM LaFave, AS Earl, Z Chiang, Y Hu, J Ding, A Brack, ... Cell 183 (4), 1103-1116. e20, 2020 | 703 | 2020 |
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ... Cancer cell 22 (2), 180-193, 2012 | 691 | 2012 |
Loss of the tumor suppressor BAP1 causes myeloid transformation A Dey, D Seshasayee, R Noubade, DM French, J Liu, MS Chaurushiya, ... Science 337 (6101), 1541-1546, 2012 | 440 | 2012 |
Loss of BAP1 function leads to EZH2-dependent transformation LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ... Nature medicine 21 (11), 1344-1349, 2015 | 366 | 2015 |
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo O Abdel-Wahab, J Gao, M Adli, A Dey, T Trimarchi, YR Chung, C Kuscu, ... Journal of Experimental Medicine 210 (12), 2641-2659, 2013 | 365 | 2013 |
Epigenomic state transitions characterize tumor progression in mouse lung adenocarcinoma LM LaFave, VK Kartha, S Ma, K Meli, I Del Priore, C Lareau, S Naranjo, ... Cancer cell 38 (2), 212-228. e13, 2020 | 180 | 2020 |
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues T Zhao, ZD Chiang, JW Morriss, LM LaFave, EM Murray, I Del Priore, ... Nature 601 (7891), 85-91, 2022 | 147 | 2022 |
JAK2 the future: therapeutic strategies for JAK-dependent malignancies LM LaFave, RL Levine Trends in pharmacological sciences 33 (11), 574-582, 2012 | 110 | 2012 |
Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung CP Concepcion, S Ma, LM LaFave, A Bhutkar, M Liu, LP DeAngelo, ... Cancer discovery 12 (2), 562-585, 2022 | 66 | 2022 |
Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis SC Meyer, MD Keller, BA Woods, LM LaFave, L Bastian, M Kleppe, ... Blood, The Journal of the American Society of Hematology 124 (14), 2280-2284, 2014 | 54 | 2014 |
Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform S Naranjo, CM Cabana, LM LaFave, R Romero, SL Shanahan, A Bhutkar, ... Genes & Development 36 (15-16), 936-949, 2022 | 17 | 2022 |
Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma I Del Priore, S Ma, J Strecker, T Jacks, LM LaFave, JD Buenrostro STAR protocols 2 (2), 100583, 2021 | 13 | 2021 |
Single-cell epigenomics reveals mechanisms of cancer progression LM LaFave, RE Savage, JD Buenrostro Annual Review of Cancer Biology 6 (1), 167-185, 2022 | 11 | 2022 |
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status" LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ... Nature medicine 22 (6), 578-579, 2016 | 11 | 2016 |
Targeting a regulator of protein homeostasis in myeloproliferative neoplasms LM LaFave, RL Levine Nature Medicine 22 (1), 20-21, 2016 | 9 | 2016 |
Mining the epigenetic landscape in ALL LM LaFave, RL Levine Nature genetics 45 (11), 1269-1270, 2013 | 7 | 2013 |
Evolution of OncoKB, a precision oncology knowledgebase SP Suehnholz, R Kundra, H Zhang, S Smith, M Nissan, Y Yao, L LaFave, ... Cancer Research 81 (13_Supplement), 99-99, 2021 | 3 | 2021 |
Unlocking PDAC initiation with AP-1 LM LaFave, JD Buenrostro Nature Cancer 2 (1), 14-15, 2021 | 2 | 2021 |
Research vision workshopping: Peer mentoring to support the transition to independence NS Bayin, KL McKinley, LM LaFave Cell 186 (7), 1295-1299, 2023 | 1 | 2023 |
Annotation of somatic genomic variants in hematologic diseases using oncokb, a precision oncology knowledgebase SP Suehnholz, R Kundra, M Roshal, W Xiao, K Petrova-Drus, M Yabe, ... Blood 134, 2148, 2019 | 1 | 2019 |