Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2 D Jansson, ACH Ng, A Fu, C Depatie, M Al Azzabi, RA Screaton Proceedings of the National Academy of Sciences 105 (29), 10161-10166, 2008 | 149 | 2008 |
Loss of Lkb1 in adult β cells increases β cell mass and enhances glucose tolerance in mice A Fu, ACH Ng, C Depatie, N Wijesekara, Y He, GS Wang, N Bardeesy, ... Cell Metabolism 10 (4), 285-295, 2009 | 143 | 2009 |
Role of AMPK in pancreatic beta cell function A Fu, CE Eberhard, RA Screaton Molecular and cellular endocrinology 366 (2), 127-134, 2013 | 110 | 2013 |
UCP1 governs liver extracellular succinate and inflammatory pathogenesis EL Mills, C Harmon, MP Jedrychowski, H Xiao, R Garrity, NV Tran, ... Nature metabolism 3 (5), 604-617, 2021 | 105 | 2021 |
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 104 | 2020 |
Role of the SIK2–p35–PJA2 complex in pancreatic β-cell functional compensation JI Sakamaki, A Fu, C Reeks, S Baird, C Depatie, M Al Azzabi, N Bardeesy, ... Nature cell biology 16 (3), 234-244, 2014 | 99 | 2014 |
Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion RJ Mailloux, A Fu, C Robson-Doucette, EM Allister, MB Wheeler, ... Journal of biological chemistry 287 (47), 39673-39685, 2012 | 74 | 2012 |
High-throughput functional genomics identifies regulators of primary human beta cell proliferation K Robitaille, JL Rourke, JE McBane, A Fu, S Baird, Q Du, T Kin, ... Journal of Biological Chemistry 291 (9), 4614-4625, 2016 | 49 | 2016 |
Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation A Fu, JC Alvarez-Perez, D Avizonis, T Kin, SB Ficarro, DW Choi, ... Nature metabolism 2 (5), 432-446, 2020 | 39 | 2020 |
CRTC2 is required for β-cell function and proliferation CE Eberhard, A Fu, C Reeks, RA Screaton Endocrinology 154 (7), 2308-2317, 2013 | 37 | 2013 |
Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, ... Cell reports 37 (8), 2021 | 30 | 2021 |
Phospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes S Ljubicic, K Polak, A Fu, J Wiwczar, B Szlyk, Y Chang, JC Alvarez-Perez, ... Cell reports 10 (4), 497-504, 2015 | 30 | 2015 |
LKB1 couples glucose metabolism to insulin secretion in mice A Fu, K Robitaille, B Faubert, C Reeks, XQ Dai, AB Hardy, KS Sankar, ... Diabetologia 58, 1513-1522, 2015 | 27 | 2015 |
Using kinomics to delineate signaling pathways: control of CRTC2/TORC2 by the AMPK family A Fu, RA Screaton Cell cycle 7 (24), 3823-3828, 2008 | 25 | 2008 |
A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells R Mailloux, A Fu, M Florian, I Petrov, Q Chen, MC Coughlan, M Laziyan, ... Toxicology 334, 81-93, 2015 | 22 | 2015 |
Regulation of the CREB coactivator TORC by the dual leucine zipper kinase at different levels M Wallbach, C Depatie, A Fu, RA Screaton, E Oetjen Cellular signalling 23 (2), 344-353, 2011 | 20 | 2011 |
Grasping for aspartate in tumour metabolism A Fu, NN Danial Nature Cell Biology 20 (7), 738-739, 2018 | 15 | 2018 |
Hydrocarbon-stitched peptide agonists of glucagon-like peptide-1 receptor GH Bird, A Fu, S Escudero, M Godes, K Opoku-Nsiah, TE Wales, ... ACS chemical biology 15 (6), 1340-1348, 2020 | 14 | 2020 |
Depletion of intranuclear rodlets in mouse models of diabetes P Milman, A Fu, RA Screaton, JM Woulfe Endocrine pathology 21, 230-235, 2010 | 3 | 2010 |
Mitochondrial bioenergetics, metabolism, and beyond in pancreatic β-cells and diabetes AM Rivera Nieves, BM Wauford, A Fu Frontiers in Molecular Biosciences 11, 1354199, 2024 | 1 | 2024 |