Long-term GABA administration induces alpha cell-mediated beta-like cell neogenesis N Ben-Othman, A Vieira, M Courtney, F Record, E Gjernes, F Avolio, ... Cell 168 (1), 73-85. e11, 2017 | 336 | 2017 |
Role of leptin in the pancreatic β-cell: effects and signaling pathways L Marroqui, A Gonzalez, P Neco, E Caballero-Garrido, E Vieira, C Ripoll, ... Journal of molecular endocrinology 49 (1), R9-R17, 2012 | 222 | 2012 |
TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic β-Cells L Marroqui, RS Dos Santos, T Fløyel, FA Grieco, I Santin, A Op de Beeck, ... Diabetes 64 (11), 3808-3817, 2015 | 181* | 2015 |
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction ML Colli, JLE Hill, L Marroquí, J Chaffey, RS Dos Santos, P Leete, ... EBioMedicine 36, 367-375, 2018 | 165 | 2018 |
Interferon-α mediates human beta cell HLA class I overexpression, endoplasmic reticulum stress and apoptosis, three hallmarks of early human type 1 diabetes L Marroqui, RS Dos Santos, A Op De Beeck, A Coomans de Brachène, ... Diabetologia 60, 656-667, 2017 | 163 | 2017 |
Expression and antiviral activity of a β-defensin-like peptide identified in the rainbow trout (Oncorhynchus mykiss) EST sequences A Falco, V Chico, L Marroqui, L Perez, JM Coll, A Estepa Molecular Immunology 45 (3), 757-765, 2008 | 134 | 2008 |
The Clock Gene Rev-erbα Regulates Pancreatic β-Cell Function: Modulation by Leptin and High-Fat Diet E Vieira, L Marroquí, TM Batista, E Caballero-Garrido, EM Carneiro, ... Endocrinology 153 (2), 592-601, 2012 | 132 | 2012 |
Pancreatic α cells are resistant to metabolic stress-induced apoptosis in type 2 diabetes L Marroqui, M Masini, B Merino, FA Grieco, I Millard, C Dubois, I Quesada, ... EBioMedicine 2 (5), 378-385, 2015 | 117 | 2015 |
BACH2, a candidate risk gene for type 1 diabetes, regulates apoptosis in pancreatic β-cells via JNK1 modulation and crosstalk with the candidate gene PTPN2 L Marroquí, I Santin, RS Dos Santos, L Marselli, P Marchetti, DL Eizirik Diabetes 63 (7), 2516-2527, 2014 | 113 | 2014 |
MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p regulate the expression of proapoptotic BH3-only proteins DP5 and PUMA in human pancreatic β-cells FA Grieco, G Sebastiani, J Juan-Mateu, O Villate, L Marroqui, L Ladrière, ... Diabetes 66 (1), 100-112, 2017 | 110 | 2017 |
Insulin hypersecretion in islets from diet-induced hyperinsulinemic obese female mice is associated with several functional adaptations in individual β-cells A Gonzalez, B Merino, L Marroquí, P Ñeco, P Alonso-Magdalena, ... Endocrinology 154 (10), 3515-3524, 2013 | 101 | 2013 |
Inhibitory effects of leptin on pancreatic α-cell function E Tudurí, L Marroquí, S Soriano, AB Ropero, TM Batista, S Piquer, ... Diabetes 58 (7), 1616-1624, 2009 | 98 | 2009 |
Glucocorticoids in Vivo Induce Both Insulin Hypersecretion and Enhanced Glucose Sensitivity of Stimulus-Secretion Coupling in Isolated Rat Islets A Rafacho, L Marroqui, SR Taboga, JLF Abrantes, LR Silveira, ... Endocrinology 151 (1), 85-95, 2010 | 97 | 2010 |
Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca2+ entry in mouse pancreatic β-cells S Villar-Pazos, J Martinez-Pinna, M Castellano-Muñoz, ... Scientific reports 7 (1), 11770, 2017 | 85 | 2017 |
Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells E Vieira, L Marroquí, ALC Figueroa, B Merino, R Fernandez-Ruiz, ... PloS one 8 (7), e69939, 2013 | 80 | 2013 |
Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells L Marroqui, M Lopes, RS dos Santos, FA Grieco, M Roivainen, ... Elife 4, e06990, 2015 | 65 | 2015 |
IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells A Coomans de Brachène, RS Dos Santos, L Marroqui, ML Colli, ... Diabetologia 61, 636-640, 2018 | 63 | 2018 |
Nutrient regulation of glucagon secretion: involvement in metabolism and diabetes L Marroqui, P Alonso-Magdalena, B Merino, E Fuentes, A Nadal, ... Nutrition research reviews 27 (1), 48-62, 2014 | 63 | 2014 |
Mitochondria as target of endocrine-disrupting chemicals: implications for type 2 diabetes L Marroqui, E Tudurí, P Alonso-Magdalena, I Quesada, Á Nadal, ... Journal of Endocrinology 239 (2), R27-R45, 2018 | 62 | 2018 |
Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress B Delatte, J Jeschke, M Defrance, M Bachman, C Creppe, E Calonne, ... Scientific reports 5 (1), 12714, 2015 | 61 | 2015 |