Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured … I Kawahata, M Yoshida, W Sun, A Nakajima, Y Lai, N Osaka, K Matsuzaki, ... Journal of neural transmission 120, 1397-1409, 2013 | 89 | 2013 |
Two distinct mechanisms for actin capping protein regulation—steric and allosteric inhibition S Takeda, S Minakata, R Koike, I Kawahata, A Narita, M Kitazawa, M Ota, ... PLoS biology 8 (7), e1000416, 2010 | 82 | 2010 |
Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons I Kawahata, L Bousset, R Melki, K Fukunaga International journal of molecular sciences 20 (21), 5358, 2019 | 51 | 2019 |
Pathogenic impact of α-synuclein phosphorylation and its kinases in α-synucleinopathies I Kawahata, DI Finkelstein, K Fukunaga International journal of molecular sciences 23 (11), 6216, 2022 | 48 | 2022 |
Degradation of tyrosine hydroxylase by the ubiquitin-proteasome system in the pathogenesis of Parkinson’s disease and dopa-responsive dystonia I Kawahata, K Fukunaga International journal of molecular sciences 21 (11), 3779, 2020 | 46 | 2020 |
Ginsenoside Rg1-induced antidepressant effects involve the protection of astrocyte gap junctions within the prefrontal cortex C Jin, ZZ Wang, H Zhou, YX Lou, J Chen, W Zuo, MT Tian, ZQ Wang, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 75, 183-191, 2017 | 44 | 2017 |
A Novel Fatty Acid-Binding Protein 5 and 7 Inhibitor Ameliorates Oligodendrocyte Injury in Multiple Sclerosis Mouse Models A Cheng, W Jia, I Kawahata, K Fukunaga Available at SSRN 3859301, 2021 | 39 | 2021 |
Fatty acid binding protein 3 enhances the spreading and toxicity of α-synuclein in mouse brain Y Yabuki, K Matsuo, I Kawahata, N Fukui, T Mizobata, Y Kawata, ... International journal of molecular sciences 21 (6), 2230, 2020 | 35 | 2020 |
Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin–proteasome system in PC12D cells I Kawahata, H Tokuoka, H Parvez, H Ichinose Journal of neural transmission 116, 1571-1578, 2009 | 35 | 2009 |
Dopamine or biopterin deficiency potentiates phosphorylation at 40Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system I Kawahata, S Ohtaku, Y Tomioka, H Ichinose, T Yamakuni Biochemical and biophysical research communications 465 (1), 53-58, 2015 | 34 | 2015 |
Dopamine D2 long receptors are critical for caveolae-mediated α-synuclein uptake in cultured dopaminergic neurons I Kawahata, T Sekimori, H Wang, Y Wang, T Sasaoka, L Bousset, R Melki, ... Biomedicines 9 (1), 49, 2021 | 30 | 2021 |
Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress A Cheng, Y Wang, Y Shinoda, I Kawahata, T Yamamoto, W Jia, ... Acta Pharmacologica Sinica 43 (3), 552-562, 2022 | 23 | 2022 |
The role of CaMKII and ERK signaling in addiction W Jia, I Kawahata, A Cheng, K Fukunaga International Journal of Molecular Sciences 22 (6), 3189, 2021 | 23 | 2021 |
Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance catecholamine … I Kawahata, T Yamakuni Toxicology 394, 84-92, 2018 | 22 | 2018 |
Epidermal fatty acid-binding protein 5 (FABP5) Involvement in alpha-synuclein-induced mitochondrial injury under oxidative stress Y Wang, Y Shinoda, A Cheng, I Kawahata, K Fukunaga Biomedicines 9 (2), 110, 2021 | 20 | 2021 |
Extracellular α‐synuclein enters dopaminergic cells by modulating flotillin‐1–assisted dopamine transporter endocytosis J Kobayashi, T Hasegawa, N Sugeno, S Yoshida, T Akiyama, K Fujimori, ... The FASEB Journal 33 (9), 10240-10256, 2019 | 20 | 2019 |
SLC10A4 is a protease-activated transporter that transports bile acids T Abe, Y Kanemitu, M Nakasone, I Kawahata, T Yamakuni, A Nakajima, ... The journal of biochemistry 154 (1), 93-101, 2013 | 20 | 2013 |
Fatty acid binding protein 5 mediates cell death by psychosine exposure through mitochondrial macropores formation in oligodendrocytes A Cheng, I Kawahata, K Fukunaga Biomedicines 8 (12), 635, 2020 | 18 | 2020 |
Novel fatty acid-binding protein 3 ligand inhibits dopaminergic neuronal death and improves motor and cognitive impairments in Parkinson's disease model mice H Haga, R Yamada, H Izumi, Y Shinoda, I Kawahata, H Miyachi, ... Pharmacology Biochemistry and Behavior 191, 172891, 2020 | 18 | 2020 |
Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS K Kamagata, R Chiba, I Kawahata, N Iwaki, S Kanbayashi, K Maeda, ... Scientific Reports 11 (1), 6643, 2021 | 16 | 2021 |