| Experimental design in systems biology, based on parameter sensitivity analysis using a monte carlo method: A case study for the tnfα-mediated nf-κ b signal transduction pathway KH Cho, SY Shin, W Kolch, O Wolkenhauer Simulation 79 (12), 726-739, 2003 | 256 | 2003 |
| Positive-and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway SY Shin, O Rath, SM Choo, F Fee, B McFerran, W Kolch, KH Cho Journal of cell science 122 (3), 425-435, 2009 | 243 | 2009 |
| Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition SY Shin, O Rath, A Zebisch, SM Choo, W Kolch, KH Cho Cancer research 70 (17), 6715-6724, 2010 | 174 | 2010 |
| Mathematical modeling of the influence of RKIP on the ERK signaling pathway C Kwang-Hyun, S Sung-Young, K Hyun-Woo, O Wolkenhauer, ... International Conference on Computational Methods in Systems Biology, 127-141, 2003 | 148 | 2003 |
| Investigations into the analysis and modeling of the TNFα-mediated NF-κB-signaling pathway KH Cho, SY Shin, HW Lee, O Wolkenhauer Genome Research 13 (11), 2413-2422, 2003 | 128 | 2003 |
| The crossregulation between ERK and PI3K signaling pathways determines the tumoricidal efficacy of MEK inhibitor JK Won, HW Yang, SY Shin, JH Lee, WD Heo, KH Cho Journal of molecular cell biology 4 (3), 153-163, 2012 | 94 | 2012 |
| Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Z Su, JG Burchfield, P Yang, SJ Humphrey, G Yang, D Francis, S Yasmin, ... Nature communications 10 (1), 5486, 2019 | 87 | 2019 |
| The switching role of β-adrenergic receptor signalling in cell survival or death decision of cardiomyocytes SY Shin, T Kim, HS Lee, JH Kang, JY Lee, KH Cho, DH Kim Nature communications 5 (1), 5777, 2014 | 72 | 2014 |
| A hidden incoherent switch regulates RCAN1 in the calcineurin–NFAT signaling network SY Shin, HW Yang, JR Kim, W Do Heo, KH Cho Journal of cell science 124 (1), 82-90, 2011 | 72 | 2011 |
| Targeting of PYK2 synergizes with EGFR antagonists in basal-like TNBC and circumvents HER3-associated resistance via the NEDD4–NDRG1 axis N Verma, AK Müller, C Kothari, E Panayotopoulou, A Kedan, ... Cancer research 77 (1), 86-99, 2017 | 70 | 2017 |
| Modelling spatially regulated β-catenin dynamics and invasion in intestinal crypts PJ Murray, JW Kang, GR Mirams, SY Shin, HM Byrne, PK Maini, KH Cho Biophysical Journal 99 (3), 716-725, 2010 | 64 | 2010 |
| MLK3 is part of a feedback mechanism that regulates different cellular responses to reactive oxygen species HS Lee, CY Hwang, SY Shin, KS Kwon, KH Cho Science signaling 7 (328), ra52-ra52, 2014 | 61 | 2014 |
| The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation D Shin, IS Kim, JM Lee, SY Shin, JH Lee, SH Baek, KH Cho Journal of Molecular Cell Biology 6 (4), 338-348, 2014 | 44 | 2014 |
| Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity SY Shin, SM Choo, D Kim, SJ Baek, O Wolkenhauer, KH Cho FEBS letters 580 (25), 5965-5973, 2006 | 44 | 2006 |
| Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis AL Kearney, DM Norris, M Ghomlaghi, M Kin Lok Wong, SJ Humphrey, ... Elife 10, e66942, 2021 | 38 | 2021 |
| Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer SY Shin, AK Müller, N Verma, S Lev, LK Nguyen PLoS computational biology 14 (6), e1006192, 2018 | 36 | 2018 |
| Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models NJ Chew, TCC Lim Kam Sian, EV Nguyen, SY Shin, J Yang, MN Hui, ... Breast Cancer Research 23, 1-20, 2021 | 28 | 2021 |
| Run-to-run overlay control of steppers in semiconductor manufacturing systems based on history data analysis and neural network modeling SJ Park, MS Lee, SY Shin, KH Cho, JT Lim, BS Cho, YH Jei, MK Kim, ... IEEE Transactions on Semiconductor Manufacturing 18 (4), 605-613, 2005 | 27 | 2005 |
| Feedback, crosstalk and competition: ingredients for emergent non-linear behaviour in the PI3K/mTOR signalling network M Ghomlaghi, A Hart, N Hoang, S Shin, LK Nguyen International journal of molecular sciences 22 (13), 6944, 2021 | 25 | 2021 |
| Control of glucocorticoid receptor levels by PTEN establishes a failsafe mechanism for tumor suppression HYK Yip, A Chee, CS Ang, SY Shin, LM Ooms, Z Mohammadi, ... Molecular Cell 80 (2), 279-295. e8, 2020 | 20 | 2020 |
