An atlas of active enhancers across human cell types and tissues R Andersson, C Gebhard, I Miguel-Escalada, I Hoof, J Bornholdt, M Boyd, ... Nature 507 (7493), 455-461, 2014 | 2647 | 2014 |
An integrated expression atlas of miRNAs and their promoters in human and mouse D De Rie, I Abugessaisa, T Alam, E Arner, P Arner, H Ashoor, G Åström, ... Nature biotechnology 35 (9), 872-878, 2017 | 559 | 2017 |
Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia C Gebhard, L Schwarzfischer, TH Pham, E Schilling, M Klug, ... Cancer research 66 (12), 6118-6128, 2006 | 242 | 2006 |
General Transcription Factor Binding at CpG Islands in Normal Cells Correlates with Resistance to De novo DNA Methylation in Cancer Cells C Gebhard, C Benner, M Ehrich, L Schwarzfischer, E Schilling, M Klug, ... Cancer research 70 (4), 1398-1407, 2010 | 162 | 2010 |
5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytes M Klug, S Schmidhofer, C Gebhard, R Andreesen, M Rehli Genome biology 14, 1-8, 2013 | 119 | 2013 |
Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels M Klug, S Heinz, C Gebhard, L Schwarzfischer, SW Krause, R Andreesen, ... Genome biology 11, 1-11, 2010 | 107 | 2010 |
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU. 1 J Minderjahn, A Schmidt, A Fuchs, R Schill, J Raithel, M Babina, ... Nature communications 11 (1), 402, 2020 | 97 | 2020 |
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells M Delacher, M Simon, L Sanderink, A Hotz-Wagenblatt, M Wuttke, ... Immunity 54 (4), 702-720. e17, 2021 | 93 | 2021 |
Rapid and sensitive detection of CpG-methylation using methyl-binding (MB)-PCR C Gebhard, L Schwarzfischer, TH Pham, R Andreesen, A Mackensen, ... Nucleic acids research 34 (11), e82-e82, 2006 | 92 | 2006 |
An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation R Avellino, M Havermans, C Erpelinck, MA Sanders, R Hoogenboezem, ... Blood, The Journal of the American Society of Hematology 127 (24), 2991-3003, 2016 | 81 | 2016 |
Whole genome bisulfite sequencing of cell-free DNA and its cellular contributors uncovers placenta hypomethylated domains TJ Jensen, SK Kim, Z Zhu, C Chin, C Gebhard, T Lu, C Deciu, ... Genome biology 16, 1-11, 2015 | 74 | 2015 |
C-Jun drives melanoma progression in PTEN wild type melanoma cells M Kappelmann-Fenzl, C Gebhard, AO Matthies, S Kuphal, M Rehli, ... Cell death & disease 10 (8), 584, 2019 | 33 | 2019 |
Consortium TF, Forrest ARR, Carninci P, Rehli M, Sandelin A. An atlas of active enhancers across human cell types and tissues R Andersson, C Gebhard, I Miguel-Escalada, I Hoof, J Bornholdt, M Boyd, ... Nature 507 (7493), 455-61, 2014 | 32 | 2014 |
The IKZF1–IRF4/IRF5 axis controls polarization of myeloma-associated macrophages D Mougiakakos, C Bach, M Böttcher, F Beier, L Röhner, A Stoll, M Rehli, ... Cancer Immunology Research 9 (3), 265-278, 2021 | 30 | 2021 |
Profiling of aberrant DNA methylation in acute myeloid leukemia reveals subclasses of CG-rich regions with epigenetic or genetic association C Gebhard, D Glatz, L Schwarzfischer, J Wimmer, S Stasik, M Nuetzel, ... Leukemia 33 (1), 26-36, 2019 | 30 | 2019 |
The epigenetic pioneer EGR2 initiates DNA demethylation in differentiating monocytes at both stable and transient binding sites K Mendes, S Schmidhofer, J Minderjahn, D Glatz, C Kiesewetter, J Raithel, ... Nature Communications 12 (1), 1556, 2021 | 25 | 2021 |
Temporal autoregulation during human PU. 1 locus SubTAD formation D Schuetzmann, C Walter, B van Riel, S Kruse, T König, T Erdmann, ... Blood, The Journal of the American Society of Hematology 132 (25), 2643-2655, 2018 | 17 | 2018 |
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML R Mulet-Lazaro, S van Herk, C Erpelinck, E Bindels, MA Sanders, ... Blood, The Journal of the American Society of Hematology 138 (2), 160-177, 2021 | 15 | 2021 |
Associations of site-specific CD4+-T-cell hypomethylation within CD40-ligand promotor and enhancer regions with disease activity of women with systemic lupus … S Vordenbäumen, A Rosenbaum, C Gebhard, J Raithel, A Sokolowski, ... Lupus 30 (1), 45-51, 2021 | 14 | 2021 |
Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation A Sorrentino, AN Menevse, T Michels, V Volpin, FC Durst, J Sax, M Xydia, ... Journal for immunotherapy of cancer 10 (5), 2022 | 11 | 2022 |