Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice J Halloran, SA Hussong, R Burbank, N Podlutskaya, KE Fischer, ... Neuroscience 223, 102-113, 2012 | 231 | 2012 |
Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer’s disease AL Lin, W Zheng, JJ Halloran, RR Burbank, SA Hussong, MJ Hart, ... Journal of Cerebral Blood Flow & Metabolism 33 (9), 1412-1421, 2013 | 230 | 2013 |
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment CE Van Skike, JB Jahrling, AB Olson, NL Sayre, SA Hussong, Z Ungvari, ... American Journal of Physiology-Heart and Circulatory Physiology, 2018 | 130 | 2018 |
Inborn errors of RNA lariat metabolism in humans with brainstem viral infection SY Zhang, NE Clark, CA Freije, E Pauwels, AJ Taggart, S Okada, ... Cell 172 (5), 952-965. e18, 2018 | 119 | 2018 |
Immunoproteasome deficiency alters retinal proteasome’s response to stress SA Hussong, RJ Kapphahn, SL Phillips, M Maldonado, DA Ferrington Journal of neurochemistry 113 (6), 1481-1490, 2010 | 109 | 2010 |
Over‐expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's‐like deficits in mice … A Pierce, N Podlutskaya, JJ Halloran, SA Hussong, PY Lin, R Burbank, ... Journal of neurochemistry 124 (6), 880-893, 2013 | 95 | 2013 |
Transformation of the proteasome with age-related macular degeneration CM Ethen, SA Hussong, C Reilly, X Feng, TW Olsen, DA Ferrington FEBS letters 581 (5), 885-890, 2007 | 95 | 2007 |
Immunoproteasome responds to injury in the retina and brain DA Ferrington, SA Hussong, H Roehrich, RJ Kapphahn, SM Kavanaugh, ... Journal of neurochemistry 106 (1), 158-169, 2008 | 83 | 2008 |
mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging CE Van Skike, AL Lin, R Roberts Burbank, JJ Halloran, SF Hernandez, ... Aging Cell 19 (1), e13057, 2020 | 71 | 2020 |
mTOR drives cerebral blood flow and memory deficits in LDLR−/− mice modeling atherosclerosis and vascular cognitive impairment JB Jahrling, AL Lin, N DeRosa, SA Hussong, CE Van Skike, M Girotti, ... Journal of Cerebral Blood Flow & Metabolism 38 (1), 58-74, 2018 | 48 | 2018 |
mTOR attenuation with rapamycin reverses neurovascular uncoupling and memory deficits in mice modeling Alzheimer's disease CE Van Skike, SA Hussong, SF Hernandez, AQ Banh, N DeRosa, ... Journal of Neuroscience 41 (19), 4305-4320, 2021 | 44 | 2021 |
Decreased in vitro Mitochondrial Function is Associated with Enhanced Brain Metabolism, Blood Flow, and Memory in Surfl-Deficient Mice AL Lin, DA Pulliam, SS Deepa, JJ Halloran, SA Hussong, RR Burbank, ... Journal of Cerebral Blood Flow & Metabolism 33 (10), 1605-1611, 2013 | 42 | 2013 |
A novel role for the immunoproteasome in retinal function SA Hussong, H Roehrich, RJ Kapphahn, M Maldonado, MT Pardue, ... Investigative Ophthalmology & Visual Science 52 (2), 714-723, 2011 | 38 | 2011 |
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy SA Hussong, AQ Banh, CE Van Skike, AO Dorigatti, SF Hernandez, ... Nature communications 14 (1), 2367, 2023 | 28 | 2023 |
Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice ND Heuss, MJ Pierson, KRC Montaniel, SW McPherson, U Lehmann, ... Journal of Neuroinflammation 11, 1-16, 2014 | 26 | 2014 |
Immunoproteasome deficiency protects in the retina after optic nerve crush NJ Schuld, SA Hussong, RJ Kapphahn, U Lehmann, H Roehrich, ... PLoS One 10 (5), e0126768, 2015 | 19 | 2015 |
Chronic inhibition of mTOR by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice J Halloran, S Hussong, R Burbank, N Podlutskaya, K Fischer, L Sloane, ... Neuroscience 223, 102, 2012 | 16 | 2012 |
Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer’s disease CE Van Skike, N DeRosa, V Galvan, SA Hussong GeroScience 45 (3), 1987-1996, 2023 | 9 | 2023 |
Mitochondrial calcium uniporter deficiency in dentate granule cells remodels neuronal metabolism and impairs reversal learning HM Rose, B Ferrán, R Ranjit, AM Masingale, DB Owen, S Hussong, ... Journal of Neurochemistry 168 (5), 592-607, 2024 | 3 | 2024 |
Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging … AO Dorigatti, SA Hussong, SF Hernandez, AM Sills, AB Salmon, V Galvan GeroScience 43, 115-124, 2021 | 2 | 2021 |