Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy RJ DeLorenzo, DA Sun, LS Deshpande Pharmacology & therapeutics 111 (1), 288-325, 2006 | 392 | 2006 |
Mechanisms of levetiracetam in the control of status epilepticus and epilepsy LS Deshpande, RJ DeLorenzo Frontiers in neurology 5, 11, 2014 | 151 | 2014 |
Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status … RE Blair, LS Deshpande, S Sombati, KW Falenski, BR Martin, ... Journal of Pharmacology and Experimental Therapeutics 317 (3), 1072-1078, 2006 | 149 | 2006 |
Traumatic brain injury causes a long‐lasting calcium (Ca2+)‐plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in … DA Sun, LS Deshpande, S Sombati, A Baranova, MS Wilson, RJ Hamm, ... European Journal of Neuroscience 27 (7), 1659-1672, 2008 | 135 | 2008 |
Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy M Raza, RE Blair, S Sombati, DS Carter, LS Deshpande, RJ DeLorenzo Proceedings of the National Academy of Sciences 101 (50), 17522-17527, 2004 | 132 | 2004 |
Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons M Raza, LS Deshpande, RE Blair, DS Carter, S Sombati, RJ DeLorenzo Neuroscience letters 418 (1), 77-81, 2007 | 127 | 2007 |
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy LS Deshpande, S Sombati, RE Blair, DS Carter, BR Martin, RJ DeLorenzo Neuroscience letters 411 (1), 11-16, 2007 | 120 | 2007 |
Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate LS Deshpande, DS Carter, RE Blair, RJ DeLorenzo Toxicological sciences 116 (2), 623-631, 2010 | 112 | 2010 |
Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture N Nagarkatti, LS Deshpande, RJ DeLorenzo Neuroscience letters 436 (3), 289-293, 2008 | 101 | 2008 |
Endocannabinoids block status epilepticus in cultured hippocampal neurons LS Deshpande, RE Blair, JM Ziobro, S Sombati, BR Martin, RJ DeLorenzo European journal of pharmacology 558 (1-3), 52-59, 2007 | 101 | 2007 |
Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry LS Deshpande, JK Lou, A Mian, RE Blair, S Sombati, E Attkisson, ... European journal of pharmacology 583 (1), 73-83, 2008 | 99 | 2008 |
Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury LS Deshpande, DA Sun, S Sombati, A Baranova, MS Wilson, E Attkisson, ... Neuroscience letters 441 (1), 115-119, 2008 | 89 | 2008 |
Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness KF Phillips, LS Deshpande Neurotoxicology 52, 127-133, 2016 | 82 | 2016 |
Prolonged exposure to WIN55, 212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture … RE Blair, LS Deshpande, S Sombati, MR Elphick, BR Martin, ... Neuropharmacology 57 (3), 208-218, 2009 | 78 | 2009 |
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication LS Deshpande, DS Carter, KF Phillips, RE Blair, RJ DeLorenzo Neurotoxicology 44, 17-26, 2014 | 56 | 2014 |
Cannabinoids: is there a potential treatment role in epilepsy? RE Blair, LS Deshpande, RJ DeLorenzo Expert opinion on pharmacotherapy 16 (13), 1911-1914, 2015 | 50 | 2015 |
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity LS Deshpande, K Phillips, B Huang, RJ DeLorenzo Neurotoxicology 44, 352-357, 2014 | 48 | 2014 |
Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis N Nagarkatti, LS Deshpande, RJ DeLorenzo Expert review of neurotherapeutics 9 (6), 813-824, 2009 | 47 | 2009 |
Comparisons of the mortality and clinical presentations of status epilepticus in private practice community and university hospital settings in Richmond, Virginia RJ DeLorenzo, B Kirmani, LS Deshpande, V Jakkampudi, AR Towne, ... Seizure 18 (6), 405-411, 2009 | 45 | 2009 |
Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons LS Deshpande, N Nagarkatti, JM Ziobro, S Sombati, RJ DeLorenzo Epilepsia 49 (10), 1795-1802, 2008 | 43 | 2008 |