A single cell transcriptomic atlas characterizes aging tissues in the mouse AO Pisco, N Schaum, A McGeever, J Karkanias, NF Neff, S Darmanis, ... Nature, 2020 | 799 | 2020 |
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain J Marschallinger, T Iram, M Zardeneta, SE Lee, B Lehallier, MS Haney, ... Nature neuroscience 23 (2), 194-208, 2020 | 725 | 2020 |
Dysregulation of brain and choroid plexus cell types in severe COVID-19 AC Yang, F Kern, PM Losada, MR Agam, CA Maat, GP Schmartz, ... Nature 595 (7868), 565-571, 2021 | 522 | 2021 |
Ageing hallmarks exhibit organ-specific temporal signatures N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ... Nature 583 (7817), 596-602, 2020 | 412 | 2020 |
Inferring causal molecular networks: empirical assessment through a community-based effort SM Hill, LM Heiser, T Cokelaer, M Unger, NK Nesser, DE Carlin, Y Zhang, ... Nature methods 13 (4), 310-318, 2016 | 243 | 2016 |
Exercise plasma boosts memory and dampens brain inflammation via clusterin Z De Miguel, N Khoury, MJ Betley, B Lehallier, D Willoughby, N Olsson, ... Nature 600 (7889), 494-499, 2021 | 214 | 2021 |
Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism O Hahn, S Grönke, TM Stubbs, G Ficz, O Hendrich, F Krueger, S Andrews, ... Genome biology 18, 1-18, 2017 | 210 | 2017 |
The sense of smell impacts metabolic health and obesity CE Riera, E Tsaousidou, J Halloran, P Follett, O Hahn, MMA Pereira, ... Cell metabolism 26 (1), 198-211. e5, 2017 | 175 | 2017 |
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 T Iram, F Kern, A Kaur, S Myneni, AR Morningstar, H Shin, MA Garcia, ... Nature 605 (7910), 509-515, 2022 | 127 | 2022 |
A nutritional memory effect counteracts the benefits of dietary restriction in old mice O Hahn, LF Drews, A Nguyen, T Tatsuta, L Gkioni, O Hendrich, Q Zhang, ... Nature metabolism 1 (11), 1059-1073, 2019 | 106 | 2019 |
GeneTrail 3: advanced high-throughput enrichment analysis N Gerstner, T Kehl, K Lenhof, A Müller, C Mayer, L Eckhart, NL Grammes, ... Nucleic acids research 48 (W1), W515-W520, 2020 | 77 | 2020 |
Ageing-associated changes in transcriptional elongation influence longevity C Debès, A Papadakis, S Grönke, Ö Karalay, LS Tain, A Mizi, ... Nature 616 (7958), 814-821, 2023 | 71 | 2023 |
Common diseases alter the physiological age-related blood microRNA profile T Fehlmann, B Lehallier, N Schaum, O Hahn, M Kahraman, Y Li, ... Nature communications 11 (1), 5958, 2020 | 65 | 2020 |
A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing YX Lu, JC Regan, J Eßer, LF Drews, T Weinseis, J Stinn, O Hahn, ... Elife 10, e62233, 2021 | 50 | 2021 |
Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder CY Kao, Z He, AS Zannas, O Hahn, C Kühne, JM Reichel, EB Binder, ... Journal of psychiatric research 76, 74-83, 2016 | 43 | 2016 |
Atlas of the aging mouse brain reveals white matter as vulnerable foci O Hahn, AG Foltz, M Atkins, B Kedir, P Moran-Losada, IH Guldner, ... Cell 186 (19), 4117-4133. e22, 2023 | 42* | 2023 |
Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice C Park, O Hahn, S Gupta, AJ Moreno, F Marino, B Kedir, D Wang, ... Nature aging 3 (9), 1067-1078, 2023 | 25 | 2023 |
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila ML Atilano, S Grönke, T Niccoli, L Kempthorne, O Hahn, J Moron-Oset, ... Elife 10, e58565, 2021 | 21 | 2021 |
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues V Wagner, F Kern, O Hahn, N Schaum, N Ludwig, T Fehlmann, A Engel, ... Nature Biotechnology 42 (1), 109-118, 2024 | 17 | 2024 |
Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster CM Weigelt, O Hahn, K Arlt, M Gruhn, AJ Jahn, J Eßer, JA Werner, C Klein, ... Life Science Alliance 2 (1), 2019 | 17 | 2019 |