Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers T Ito, MJ Young, R Li, S Jain, A Wernitznig, JM Krill-Burger, CT Lemke, ... Nature genetics 53 (12), 1664-1672, 2021 | 91 | 2021 |
Molecular basis for substrate recruitment to the PRMT5 methylosome KM Mulvaney, C Blomquist, N Acharya, R Li, MJ Ranaghan, M O’Keefe, ... Molecular Cell 81 (17), 3481-3495. e7, 2021 | 50 | 2021 |
Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders X Wu, X Yang, Y Xiong, R Li, T Ito, TA Ahmed, Z Karoulia, C Adamopoulos, ... Nature Cancer 2 (4), 429-443, 2021 | 41 | 2021 |
Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations R Barfield, H Wang, Y Liu, JA Brody, B Swenson, R Li, TM Bartz, ... Sleep 42 (8), zsz101, 2019 | 36 | 2019 |
Comparative optimization of combinatorial CRISPR screens R Li, O Klingbeil, D Monducci, MJ Young, DJ Rodriguez, Z Bayyat, ... Nature Communications 13 (1), 2469, 2022 | 21 | 2022 |
Sequencing analysis at 8p23 identifies multiple rare variants in DLC1 associated with sleep-related oxyhemoglobin saturation level J Liang, BE Cade, KY He, H Wang, J Lee, T Sofer, S Williams, R Li, ... The American Journal of Human Genetics 105 (5), 1057-1068, 2019 | 14 | 2019 |
Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities L Chang, NY Jung, A Atari, DJ Rodriguez, D Kesar, TY Song, MG Rees, ... Nature Genetics 55 (10), 1709-1720, 2023 | 13 | 2023 |
A composite sleep and pulmonary phenotype predicting hypertension R Li, M Rueschman, DJ Gottlieb, S Redline, T Sofer EBioMedicine 68, 2021 | 11 | 2021 |
Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy T Sofer, R Li, R Joehanes, H Lin, AC Gower, H Wang, N Kurniansyah, ... EBioMedicine 56, 2020 | 6 | 2020 |
Utility of Continuous Disease Subtyping Systems for Improved Evaluation of Etiologic Heterogeneity R Li, T Ugai, L Xu, D Zucker, S Ogino, M Wang Cancers 14 (7), 1811, 2022 | 2 | 2022 |
Abstract B037: Hit-finding by Cysteine-Scanning (HCS): A method for finding druggable pockets LM van Tienen, S Bayoumi, K Muneeruddin, N Leymarie, D Kornfilt, ... Molecular Cancer Research 21 (5_Supplement), B037-B037, 2023 | | 2023 |