| Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders L Antonioli, R Colucci, C La Motta, M Tuccori, O Awwad, F Da Settimo, ... Current drug targets 13 (6), 842-862, 2012 | 176 | 2012 |
| Recent advances in the development of dual topoisomerase I and II inhibitors as anticancer drugs S Salerno, F Da Settimo, S Taliani, F Simorini, C La Motta, G Fornaciari, ... Current medicinal chemistry 17 (35), 4270-4290, 2010 | 167 | 2010 |
| Pyrido[1,2-a]pyrimidin-4-one Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors Exhibiting Antioxidant Activity C La Motta, S Sartini, L Mugnaini, F Simorini, S Taliani, S Salerno, ... Journal of Medicinal Chemistry 50 (20), 4917-4927, 2007 | 163 | 2007 |
| FOXD1–ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells P Cheng, J Wang, I Waghmare, S Sartini, V Coviello, Z Zhang, SH Kim, ... Cancer research 76 (24), 7219-7230, 2016 | 146 | 2016 |
| Inhibition of adenosine deaminase attenuates inflammation in experimental colitis L Antonioli, M Fornai, R Colucci, N Ghisu, F Da Settimo, G Natale, ... Journal of Pharmacology and Experimental Therapeutics 322 (2), 435-442, 2007 | 137 | 2007 |
| Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic … R Ottanà, R Maccari, M Giglio, A Del Corso, M Cappiello, U Mura, ... European journal of medicinal chemistry 46 (7), 2797-2806, 2011 | 132 | 2011 |
| Sampling protein motion and solvent effect during ligand binding V Limongelli, L Marinelli, S Cosconati, C La Motta, S Sartini, L Mugnaini, ... Proceedings of the National Academy of Sciences 109 (5), 1467-1472, 2012 | 118 | 2012 |
| Novel Pyrazolopyrimidine Derivatives as Tyrosine Kinase Inhibitors with Antitumoral Activity in Vitro and in Vivo in Papillary Dedifferentiated Thyroid Cancer A Antonelli, G Bocci, C La Motta, SM Ferrari, P Fallahi, A Fioravanti, ... The Journal of Clinical Endocrinology & Metabolism 96 (2), E288-E296, 2011 | 102 | 2011 |
| Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis F Da Settimo, F Simorini, S Taliani, C La Motta, AM Marini, S Salerno, ... Journal of medicinal chemistry 51 (18), 5798-5806, 2008 | 102 | 2008 |
| Novel treatments for anaplastic thyroid carcinoma SM Ferrari, G Elia, F Ragusa, I Ruffilli, C La Motta, SR Paparo, A Patrizio, ... Gland surgery 9 (Suppl 1), S28, 2020 | 93 | 2020 |
| Synthesis of pyrrolo [3, 4-c] pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors A Da Settimo, G Primofiore, F Da Settimo, F Simorini, C La Motta, ... European journal of medicinal chemistry 31 (1), 49-58, 1996 | 84 | 1996 |
| Aldose reductase inhibitors: 2013-present L Quattrini, C La Motta Expert opinion on therapeutic patents 29 (3), 199-213, 2019 | 78 | 2019 |
| Indole amide derivatives: synthesis, structure–activity relationships and molecular modelling studies of a new series of histamine H1-receptor antagonists S Battaglia, E Boldrini, F Da Settimo, G Dondio, C La Motta, AM Marini, ... European journal of medicinal chemistry 34 (2), 93-105, 1999 | 76 | 1999 |
| Design, synthesis and biological evaluation of new classes of thieno [3, 2-d] pyrimidinone and thieno [1, 2, 3] triazine as inhibitor of vascular endothelial growth factor … E Perspicace, V Jouan-Hureaux, R Ragno, F Ballante, S Sartini, ... European journal of medicinal chemistry 63, 765-781, 2013 | 71 | 2013 |
| 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: A New Class of Selective A1 Adenosine Receptor Antagonists F Da Settimo, G Primofiore, S Taliani, AM Marini, C La Motta, E Novellino, ... Journal of medicinal chemistry 44 (3), 316-327, 2001 | 71 | 2001 |
| Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists B Cosimelli, G Greco, M Ehlardo, E Novellino, F Da Settimo, S Taliani, ... Journal of medicinal chemistry 51 (6), 1764-1770, 2008 | 67 | 2008 |
| 2-(Benzimidazol-2-yl)quinoxalines: A Novel Class of Selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching E Novellino, B Cosimelli, M Ehlardo, G Greco, M Iadanza, A Lavecchia, ... Journal of medicinal chemistry 48 (26), 8253-8260, 2005 | 65 | 2005 |
| New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation S Taliani, F Simorini, V Sergianni, C La Motta, F Da Settimo, B Cosimelli, ... Journal of Medicinal Chemistry 50 (2), 404-407, 2007 | 64 | 2007 |
| How reliable are current docking approaches for structure-based drug design? Lessons from aldose reductase M Zentgraf, H Steuber, C Koch, C La Motta, S Stefania, C Sotriffer, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46 (19), 3575-3578, 2007 | 64 | 2007 |
| Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors F Da Settimo, G Primofiore, C La Motta, S Sartini, S Taliani, F Simorini, ... Journal of medicinal chemistry 48 (22), 6897-6907, 2005 | 62 | 2005 |
