Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors F Hubálek, C Binda, A Khalil, M Li, A Mattevi, N Castagnoli, ... Journal of biological chemistry 280 (16), 15761-15766, 2005 | 265 | 2005 |
Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves AA Khalil, S Steyn, N Castagnoli Chemical research in toxicology 13 (1), 31-35, 2000 | 119 | 2000 |
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors AK • Arwa Hammuda, Raed Shalaby, Stefano Rovida, Dale E. Edmondson, Claudia ... European Journal of Medicinal Chemistry 114, 162-169, 2016 | 96 | 2016 |
Substituted Quinazolines, Part 2. Synthesis and In‐Vitro Anticancer Evaluation of New 2‐Substituted Mercapto‐3H‐quinazoline Analogs AA Khalil, SGA Hamide, AM Al‐Obaid, HI El‐Subbagh Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2003 | 76 | 2003 |
Purification and characterization of 0-amylase from AF Afifi, EA Kamel, AA Khalil, M Fawzi, MM Housery Glob. J. Biotechnol. Biochem 3 (1), 14-21, 2008 | 65 | 2008 |
Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke AA Khalil, B Davies, N Castagnoli Jr Bioorganic & medicinal chemistry 14 (10), 3392-3398, 2006 | 61 | 2006 |
Studies on the interactions of tobacco leaf and tobacco smoke constituents and monoamine oxidase K Castagnoli, SJ Steyn, G Magnin, CJ Van Der Schyf, I Fourie, A Khalil, ... Neurotoxicity research 4, 151-160, 2002 | 52 | 2002 |
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs R Shalaby, JP Petzer, A Petzer, UM Ashraf, E Atari, F Alasmari, ... Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 863-876, 2019 | 49 | 2019 |
Design, synthesis, and validation of novel nitrogen-based chalcone analogs against triple negative breast cancer D Elkhalifa, AB Siddique, M Qusa, F Cyprian, K El Sayed, F Alali, ... European Journal of Medicinal Chemistry 187, 111954, 2020 | 46 | 2020 |
Semisynthetic studies on the manzamine alkaloids KAE Sayed, AA Khalil, M Yousaf, G Labadie, GM Kumar, SG Franzblau, ... Journal of natural products 71 (3), 300-308, 2008 | 37 | 2008 |
Monoamine oxidase inhibitors extracted from tobacco smoke as neuroprotective factors for potential treatment of Parkinson’s disease Y Sari, A Khalil CNS & Neurological Disorders - Drug Targets 14 (6), 777-785, 2015 | 36 | 2015 |
Substituted Quinazolines. Part 1. Synthesis and Antitumor Activity of Certain Substituted 2‐Mercapto‐4 (3H)‐quinazolinone Analogues. SGA Hamid, HA El‐Obeid, KA Al‐Rashood, AA Khalil, HI El‐Subbagh ChemInform 33 (20), no-no, 2002 | 24 | 2002 |
Structure–activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones K Metwally, A Khalil, A Sallam, H Pratsinis, D Kletsas, K El Sayed Medicinal Chemistry Research 22, 4481-4491, 2013 | 20 | 2013 |
Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro AS Hammad, S Ravindran, A Khalil, S Munusamy Cell Stress and Chaperones 22 (3), 417-428, 2017 | 17 | 2017 |
Targeting triple negative breast cancer heterogeneity with chalcones: a molecular insight D Elkhalifa, F Alali, AE Al Moustafa, A Khalil Journal of drug targeting 27 (8), 830-838, 2019 | 16 | 2019 |
A novel and selective monoamine oxidase B substrate JM Rimoldi, SG Puppali, E Isin, P Bissel, A Khalil, N Castagnoli Jr Bioorganic & medicinal chemistry 13 (20), 5808-5813, 2005 | 14 | 2005 |
Substituted Quinazolines, 1. Synthesis and antitumor activity of certain substituted 2-mercapto-4 (3H)-quinazolinone analogs SG Abdel Hamid, HA El-Obeid, KA Al-Rashood, AA Khalil, HI El-Subbagh Scientia Pharmaceutica 69 (4), 351-366, 2001 | 13 | 2001 |
Derivative Spectrophotometry for Stability-Indicating Determination of Norfloxacin in Bulk Form and Tablets KA Rashood, EM Abdel-Moety, OA Al-Deeb, AA Khalil SCIENTIA PHARMACEUTICA 62, 225-225, 1994 | 11 | 1994 |
Stereochemical studies on the novel monoamine oxidase B substrates (1R, 6S)-and (1S, 6R)-3-methyl-6-phenyl-3-aza-bicyclo [4.1. 0] heptane P Bissel, A Khalil, JM Rimoldi, K Igarashi, D Edmondson, A Miller, ... Bioorganic & medicinal chemistry 16 (7), 3557-3564, 2008 | 10 | 2008 |
Teucrium polium plant extract provokes substantial cytotoxicity at the early stage of embryonic development SS Al-Qahdi, N Alzohari, AY Alsaid, AA Ashour, T Aboulkassim, S Vranic, ... Bosnian journal of basic medical sciences 19 (1), 67, 2019 | 9 | 2019 |