Regulatory T cells mediate specific suppression by depleting peptide–MHC class II from dendritic cells B Akkaya, Y Oya, M Akkaya, J Al Souz, AH Holstein, O Kamenyeva, ... Nature immunology 20 (2), 218-231, 2019 | 295 | 2019 |
Second signals rescue B cells from activation-induced mitochondrial dysfunction and death M Akkaya, J Traba, AS Roesler, P Miozzo, B Akkaya, BP Theall, H Sohn, ... Nature immunology 19 (8), 871-884, 2018 | 242 | 2018 |
Toll-like receptor 9 antagonizes antibody affinity maturation M Akkaya, B Akkaya, AS Kim, P Miozzo, H Sohn, M Pena, AS Roesler, ... Nature immunology 19 (3), 255-266, 2018 | 78 | 2018 |
An optimized protocol to analyze glycolysis and mitochondrial respiration in lymphocytes J Traba, P Miozzo, B Akkaya, SK Pierce, M Akkaya Journal of visualized experiments: JoVE, 54918, 2016 | 64 | 2016 |
Increased mitochondrial biogenesis and reactive oxygen species production accompany prolonged CD4+ T cell activation B Akkaya, AS Roesler, P Miozzo, BP Theall, J Al Souz, MG Smelkinson, ... The Journal of Immunology 201 (11), 3294-3306, 2018 | 56 | 2018 |
Regulatory T cells: Master thieves of the immune system B Akkaya, EM Shevach Cellular immunology 355, 104160, 2020 | 48 | 2020 |
Exhaust the exhausters: Targeting regulatory T cells in the tumor microenvironment BR McRitchie, B Akkaya Frontiers in immunology 13, 940052, 2022 | 43 | 2022 |
Dissection of agonistic and blocking effects of CD200 receptor antibodies M Akkaya, ML Aknin, B Akkaya, AN Barclay PLoS One 8 (5), e63325, 2013 | 30 | 2013 |
B cells produce type 1 IFNs in response to the TLR9 agonist CpG-A conjugated to cationic lipids M Akkaya, B Akkaya, P Miozzo, M Rawat, M Pena, PW Sheehan, AS Kim, ... The Journal of Immunology 199 (3), 931-940, 2017 | 29 | 2017 |
A simple, versatile antibody-based barcoding method for flow cytometry B Akkaya, P Miozzo, AH Holstein, EM Shevach, SK Pierce, M Akkaya The Journal of Immunology 197 (5), 2027-2038, 2016 | 27 | 2016 |
T cell‐dependent antigen adjuvanted with DOTAP‐CpG‐B but not DOTAP‐CpG‐A induces robust germinal center responses and high affinity antibodies in mice M Akkaya, B Akkaya, PW Sheehan, P Miozzo, M Pena, CF Qi, ... European Journal of Immunology 47 (11), 1890-1899, 2017 | 18 | 2017 |
Ex-vivo iTreg differentiation revisited: Convenient alternatives to existing strategies B Akkaya, AH Holstein, C Isaac, MP Maz, DD Glass, EM Shevach, ... Journal of immunological methods 441, 67-71, 2017 | 11 | 2017 |
Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases AH Lippert, C Paluch, M Gaglioni, MT Vuong, J McColl, E Jenkins, ... Immunity 57 (2), 256-270. e10, 2024 | 9 | 2024 |
Unique interaction dynamics and peptide-MHC class II (pMHC II) transendocytosis lead to antigen-specific T regulatory cell (Treg)-mediated suppression B Akkaya, M Akkaya, O Kamenyeva, J Kabat, DW Dorward, AH Holstein, ... The Journal of Immunology 198 (1_Supplement), 80.8-80.8, 2017 | 6 | 2017 |
Tregs orchestrate antigen specific suppression via stripping cognate peptide-MHCII from the DC surface B Akkaya, M Akkaya, Y Oya, JA Al Souz, AH Holstein, O Kamenyeva, ... The Journal of Immunology 200 (1_Supplement), 47.20-47.20, 2018 | 4 | 2018 |
Modulation of the PD-1 pathway by inhibitory antibody superagonists B Akkaya | 4 | 2012 |
Visualizing the Dynamics of T Cell–Dendritic Cell Interactions in Intact Lymph Nodes by Multiphoton Confocal Microscopy B Akkaya, O Kamenyeva, J Kabat, R Kissinger Confocal Microscopy: Methods and Protocols, 243-263, 2021 | 3 | 2021 |
Regulatory T cells perform antigen specific suppression by depleting cognate peptide-MHC class II via trogocytosis B Akkaya, Y Oya, M Akkaya, JA Al Souz, AH Holstein, J Kabat, ... The Journal of Immunology 202 (1_Supplement), 57.17-57.17, 2019 | 3 | 2019 |
In vivo characterization of inhibitory anti-PD-1 antibody superagonists B Akkaya, S Davis, R Cornall | 2 | 2011 |
Prolonged activation in CD4+ T cells results in extensive mitochondrial remodeling despite the metabolic dominance of aerobic glycolysis B Akkaya, A Roesler, BP Theall, JA Al Souz, P Miozzo, J Traba, ... The Journal of Immunology 202 (1_Supplement), 128.6-128.6, 2019 | 1 | 2019 |