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Lenno Krenning
Lenno Krenning
在 nki.nl 的电子邮件经过验证
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引用次数
引用次数
年份
The same, only different–DNA damage checkpoints and their reversal throughout the cell cycle
IA Shaltiel, L Krenning, W Bruinsma, RH Medema
Journal of cell science 128 (4), 607-620, 2015
3772015
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ...
Molecular cell 68 (1), 210-223. e6, 2017
2312017
Transient activation of p53 in G2 phase is sufficient to induce senescence
L Krenning, FM Feringa, IA Shaltiel, J van den Berg, RH Medema
Molecular cell 55 (1), 59-72, 2014
2212014
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore
J Espeut, DK Cheerambathur, L Krenning, K Oegema, A Desai
Journal of Cell Biology 196 (4), 469-482, 2012
1722012
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies
N Battich, J Beumer, B De Barbanson, L Krenning, CS Baron, ...
Science 367 (6482), 1151-1156, 2020
1172020
Life or death after a break: what determines the choice?
L Krenning, J van den Berg, RH Medema
Molecular cell 76 (2), 346-358, 2019
912019
Chromosomes trapped in micronuclei are liable to segregation errors
M Soto, I García-Santisteban, L Krenning, RH Medema, JA Raaijmakers
Journal of cell science 131 (13), jcs214742, 2018
892018
Recovery from a DNA‐damage‐induced G2 arrest requires Cdk‐dependent activation of FoxM1
M Alvarez‐Fernández, VA Halim, L Krenning, M Aprelia, S Mohammed, ...
EMBO reports 11 (6), 452-458, 2010
672010
Persistent repair intermediates induce senescence
FM Feringa, JA Raaijmakers, MA Hadders, C Vaarting, L Macurek, ...
Nature Communications 9 (1), 3923, 2018
642018
Pharmaceutical-grade rigosertib is a microtubule-destabilizing agent
M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ...
Molecular cell 79 (1), 191-198. e3, 2020
342020
Hypersensitivity to DNA damage in antephase as a safeguard for genome stability
FM Feringa, L Krenning, A Koch, J Van Den Berg, B Van Den Broek, ...
Nature Communications 7 (1), 12618, 2016
322016
Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition
L Krenning, S Sonneveld, ME Tanenbaum
Elife 11, e71356, 2022
25*2022
Resistance of hypoxic cells to ionizing radiation is mediated in part via hypoxia-induced quiescence
A Menegakis, R Klompmaker, C Vennin, A Arbusà, M Damen, ...
Cells 10 (3), 610, 2021
252021
Double-strand break toxicity is chromatin context independent
A Friskes, L Koob, L Krenning, TM Severson, ES Koeleman, X Vergara, ...
Nucleic Acids Research 50 (17), 9930-9947, 2022
202022
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
M Hornsveld, FM Feringa, L Krenning, J van den Berg, LMM Smits, ...
Cell Reports 34 (4), 2021
122021
Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells
I García-Santisteban, A Llopis, L Krenning, J Vallejo-Rodríguez, ...
BMC biology 19, 1-13, 2021
102021
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity
Z Pogacar, JL Johnson, L Krenning, G De Conti, F Jochems, C Lieftink, ...
PLoS One 17 (9), e0273182, 2022
92022
DNA end-resection in highly accessible chromatin produces a toxic break
J van den Berg, SEP Joosten, YS Kim, AG Manjón, L Krenning, L Koob, ...
BioRxiv, 691857, 2019
92019
MND1 enables homologous recombination in somatic cells primarily outside the context of replication
L Koob, A Friskes, L van Bergen, FM Feringa, B van den Broek, ...
Molecular Oncology 17 (7), 1192-1211, 2023
62023
Enter the nucleus to exit the cycle: Comment on: Müllers E, et al. Cell Cycle 2014; 13: 2733-43; http://dx. doi. org/10.4161/15384101.2015. 945831
L Krenning, RH Medema
Cell Cycle 13 (17), 2651-52, 2014
42014
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