Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE S Parhizkar, T Arzberger, M Brendel, G Kleinberger, M Deussing, C Focke, ... Nature neuroscience 22 (2), 191-204, 2019 | 496 | 2019 |
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia C Wang, M Xiong, M Gratuze, X Bao, Y Shi, PS Andhey, M Manis, ... Neuron 109 (10), 1657-1674. e7, 2021 | 229 | 2021 |
Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegeneration M Gratuze, CEG Leyns, AD Sauerbeck, MK St-Pierre, M Xiong, N Kim, ... The Journal of clinical investigation 130 (9), 4954-4968, 2020 | 183 | 2020 |
Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation F Liao, A Li, M Xiong, N Bien-Ly, H Jiang, Y Zhang, MB Finn, R Hoyle, ... The Journal of clinical investigation 128 (5), 2144-2155, 2018 | 158 | 2018 |
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function M Xiong, H Jiang, JR Serrano, ER Gonzales, C Wang, M Gratuze, ... Science translational medicine 13 (581), eabd7522, 2021 | 116 | 2021 |
Secreted amyloid precursor protein-alpha can restore novel object location memory and hippocampal LTP in aged rats M Xiong, OD Jones, K Peppercorn, SM Ohline, WP Tate, WC Abraham Neurobiology of learning and memory 138, 291-299, 2017 | 47 | 2017 |
APOE antibody inhibits Aβ‐associated tau seeding and spreading in a mouse model M Gratuze, H Jiang, C Wang, M Xiong, X Bao, DM Holtzman Annals of neurology 91 (6), 847-852, 2022 | 22 | 2022 |
Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy M Xiong, C Wang, M Gratuze, F Saadi, X Bao, ME Bosch, C Lee, H Jiang, ... Molecular neurodegeneration 18 (1), 17, 2023 | 18 | 2023 |
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains TM Bigley, M Xiong, M Ali, Y Chen, C Wang, JR Serrano, A Eteleeb, ... Molecular neurodegeneration 17 (1), 10, 2022 | 13 | 2022 |
Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer’s disease and multiple sclerosis A Etxeberria, YAA Shen, S Vito, SM Silverman, J Imperio, G Lalehzadeh, ... Journal of Neuroscience 44 (29), 2024 | 3 | 2024 |
A fluorescent splice-switching mouse model enables high-throughput, sensitive quantification of antisense oligonucleotide delivery and activity AE Byrnes, F Roudnicky, A Gogineni, AL Soung, M Xiong, M Hayne, ... Cell Reports Methods 4 (1), 2024 | 2 | 2024 |
Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE S Parhizkar, T Arzberger, M Brendel, G Kleinberger, M Deussing, C Focke, ... Nature neuroscience 27 (9), 1858-1859, 2024 | | 2024 |
Apolipoprotein E Immunotherapy for the Preclinical Treatment of Alzheimer Disease and Cerebral Amyloid Angiopathy M Xiong Washington University in St. Louis, 2021 | | 2021 |
Effects of human LDLR overexpression on apoE-related tau pathology and brain dysfunction A Li, R Spellman, X Bao, N Scott, M Manis, MB Finn, M Xiong, JR Serrano, ... The Journal of Immunology 204 (1_Supplement), 64.6-64.6, 2020 | | 2020 |
Effects of Human LDLR Overexpression on ApoE-Related Tau Pathology and Brain Dysfunction C Wang, A Li, S Nathan, R Spellman, M Melissa, MB Finn, Y Shi, M Xiong, ... ANNALS OF NEUROLOGY 86, S57-S57, 2019 | | 2019 |
ApoE4 Immunotherapy Reduced Vascular Amyloid Pathology without Inducing Microhemorrhages M Xiong, F Liao, A Li, H Jiang, N Bien-Ly, R Hoyle, JR Serrano, P Sullivan, ... ANNALS OF NEUROLOGY 86, S45-S46, 2019 | | 2019 |
Proceedings of the 226th Otago Medical School Research Society Meeting-Masters/Honours Student Speaker Awards; 5 Nov 2014 T Hall, D Schwenke, M Xiong, O Jones, K Peppercorn, W Tate, ... 226th Otago Medical School Research Society Meeting-Masters/Honours Student …, 2014 | | 2014 |