| Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome S Le Scouarnec, M Karakachoff, JB Gourraud, P Lindenbaum, S Bonnaud, ... Human molecular genetics 24 (10), 2757-2763, 2015 | 146 | 2015 |
| Sphingosine-1-phosphate activates the AKT pathway to protect small intestines from radiation-induced endothelial apoptosis S Bonnaud, C Niaudet, F Legoux, I Corre, G Delpon, X Saulquin, Z Fuks, ... Cancer research 70 (23), 9905-9915, 2010 | 96 | 2010 |
| Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage–induced mitotic death S Bonnaud, C Niaudet, G Pottier, MH Gaugler, J Millour, J Barbet, ... Cancer research 67 (4), 1803-1811, 2007 | 81 | 2007 |
| Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility J Barc, R Tadros, C Glinge, DY Chiang, M Jouni, F Simonet, SJ Jurgens, ... Nature genetics 54 (3), 232-239, 2022 | 78 | 2022 |
| ABT-737 Induces Apoptosis in Mantle Cell Lymphoma Cells with a Bcl-2high/Mcl-1low Profile and Synergizes with Other Antineoplastic Agents C Touzeau, C Dousset, L Bodet, P Gomez-Bougie, S Bonnaud, A Moreau, ... Clinical Cancer Research 17 (18), 5973-5981, 2011 | 67 | 2011 |
| Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis C Niaudet, S Bonnaud, M Guillonneau, S Gouard, MH Gaugler, S Dutoit, ... Cellular Signalling 33, 10-21, 2017 | 62 | 2017 |
| Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis S Thériault, C Dina, D Messika-Zeitoun, S Le Scouarnec, R Capoulade, ... Circulation: Genomic and Precision Medicine 12 (10), e002617, 2019 | 61 | 2019 |
| Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I X Daumy, MY Amarouch, P Lindenbaum, S Bonnaud, E Charpentier, ... International journal of cardiology 207, 349-358, 2016 | 59 | 2016 |
| RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration M Rousseau, MH Gaugler, A Rodallec, S Bonnaud, F Paris, I Corre Biochemical and biophysical research communications 414 (4), 750-755, 2011 | 58 | 2011 |
| Rare coding variants in ANGPTL6 are associated with familial forms of intracranial aneurysm R Bourcier, S Le Scouarnec, S Bonnaud, M Karakachoff, E Bourcereau, ... The American Journal of Human Genetics 102 (1), 133-141, 2018 | 55 | 2018 |
| Intestinal epithelial cell dysfunction is mediated by an endothelial-specific radiation-induced bystander effect MH Gaugler, M Neunlist, S Bonnaud, P Aubert, M Benderitter, F Paris Radiation Research 167 (2), 185-193, 2007 | 53 | 2007 |
| RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome N Belbachir, V Portero, ZR Al Sayed, JB Gourraud, F Dilasser, L Jesel, ... European Heart Journal 40 (37), 3081-3094, 2019 | 43 | 2019 |
| Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome V Portero, S Le Scouarnec, Z Es‐Salah‐Lamoureux, S Burel, ... Journal of the American Heart Association 5 (6), e003122, 2016 | 32 | 2016 |
| Progressive atrial conduction defects associated with bone malformation caused by a connexin-45 mutation A Seki, T Ishikawa, X Daumy, H Mishima, J Barc, R Sasaki, K Nishii, ... Journal of the American College of Cardiology 70 (3), 358-370, 2017 | 28 | 2017 |
| Paradoxical effect of lenalidomide on cytokine/growth factor profiles in multiple myeloma S Maiga, P Gomez-Bougie, S Bonnaud, C Gratas, P Moreau, S Le Gouill, ... British journal of cancer 108 (9), 1801-1806, 2013 | 23 | 2013 |
| 3’RNA sequencing for robust and low-cost gene expression profiling E Charpentier, M Cornec, S Dumont, D Meistermann, P Bordron, L David, ... | 15 | 2021 |
| Genetic population structure across Brittany and the downstream Loire basin provides new insights on the demographic history of Western Europe I Alves, J Giemza, M Blum, C Bernhardsson, S Chatel, M Karakachoff, ... bioRxiv, 2022.02. 03.478491, 2022 | 8 | 2022 |
| Rational for the use of a targeted-therapy using ABT-737 in mantle-cell lymphoma C Touzeau, C Dousset, L Bodet, S Bonnaud, P Gomez-Bougie, ... Blood 116 (21), 770, 2010 | 3 | 2010 |
| Burden of rare variants in arrhythmogenic cardiomyopathy with right dominant form‐associated genes provides new insights for molecular diagnosis and clinical management A Goudal, M Karakachoff, P Lindenbaum, E Baron, S Bonnaud, F Kyndt, ... Human Mutation 43 (9), 1333-1342, 2022 | 2 | 2022 |
| Radiation induces p38-mediated endothelial cell death through ceramide generation and membrane remodeling C Niaudet, S Bonnaud, S Gouard, MH Gaugler, I Corre, F Paris Radioprotection 43 (5), 106, 2008 | 2 | 2008 |
