The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 176, S21-S141, 2019 | 771 | 2019 |
A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells C Hoffmann, G Gaietta, M Bünemann, SR Adams, S Oberdorff-Maass, ... Nature methods 2 (3), 171-176, 2005 | 630 | 2005 |
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis S Ferrandon, TN Feinstein, M Castro, B Wang, R Bouley, JT Potts, ... Nature chemical biology 5 (10), 734-742, 2009 | 611 | 2009 |
Measurement of the millisecond activation switch of G protein–coupled receptors in living cells JP Vilardaga, M Bünemann, C Krasel, M Castro, MJ Lohse Nature biotechnology 21 (7), 807-812, 2003 | 531 | 2003 |
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 474 | 2021 |
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 420 | 2017 |
Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling JP Vilardaga, VO Nikolaev, K Lorenz, S Ferrandon, Z Zhuang, MJ Lohse Nature chemical biology 4 (2), 126-131, 2008 | 312 | 2008 |
Retromer terminates the generation of cAMP by internalized PTH receptors TN Feinstein, VL Wehbi, JA Ardura, DS Wheeler, S Ferrandon, ... Nature chemical biology 7 (5), 278-284, 2011 | 245 | 2011 |
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin TN Feinstein, N Yui, MJ Webber, VL Wehbi, HP Stevenson, JD King, ... Journal of Biological Chemistry 288 (39), 27849-27860, 2013 | 240 | 2013 |
Endosomal generation of cAMP in GPCR signaling JP Vilardaga, FG Jean-Alphonse, TJ Gardella Nature chemical biology 10 (9), 700-706, 2014 | 233 | 2014 |
Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor T Dean, JP Vilardaga, JT Potts Jr, TJ Gardella Molecular endocrinology 22 (1), 156-166, 2008 | 231 | 2008 |
PTH receptor-1 signalling—mechanistic insights and therapeutic prospects RW Cheloha, SH Gellman, JP Vilardaga, TJ Gardella Nature Reviews Endocrinology 11 (12), 712-724, 2015 | 225 | 2015 |
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism M Castro, VO Nikolaev, D Palm, MJ Lohse, JP Vilardaga Proceedings of the National Academy of Sciences 102 (44), 16084-16089, 2005 | 204 | 2005 |
Structure and dynamics of the active human parathyroid hormone receptor-1 LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ... Science 364 (6436), 148-153, 2019 | 202 | 2019 |
Molecular basis of inverse agonism in a G protein–coupled receptor JP Vilardaga, R Steinmeyer, GS Harms, MJ Lohse Nature chemical biology 1 (1), 25-28, 2005 | 183 | 2005 |
Real-time optical recording of β1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol F Rochais, JP Vilardaga, VO Nikolaev, M Bünemann, MJ Lohse, ... The Journal of clinical investigation 117 (1), 229-235, 2007 | 181 | 2007 |
Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex VL Wehbi, HP Stevenson, TN Feinstein, G Calero, G Romero, ... Proceedings of the National Academy of Sciences 110 (4), 1530-1535, 2013 | 180 | 2013 |
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation M Okazaki, S Ferrandon, JP Vilardaga, ML Bouxsein, JT Potts Jr, ... Proceedings of the National Academy of Sciences 105 (43), 16525-16530, 2008 | 169 | 2008 |
Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm JP Vilardaga, G Romero, PA Friedman, TJ Gardella Cellular and Molecular Life Sciences 68, 1-13, 2011 | 159 | 2011 |
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors MJ Lohse, VO Nikolaev, P Hein, C Hoffmann, JP Vilardaga, M Bünemann Trends in pharmacological sciences 29 (3), 159-165, 2008 | 157 | 2008 |