关注
Jean-Pierre Vilardaga
Jean-Pierre Vilardaga
未知所在单位机构
在 pitt.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
7712019
A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells
C Hoffmann, G Gaietta, M Bünemann, SR Adams, S Oberdorff-Maass, ...
Nature methods 2 (3), 171-176, 2005
6302005
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
S Ferrandon, TN Feinstein, M Castro, B Wang, R Bouley, JT Potts, ...
Nature chemical biology 5 (10), 734-742, 2009
6112009
Measurement of the millisecond activation switch of G protein–coupled receptors in living cells
JP Vilardaga, M Bünemann, C Krasel, M Castro, MJ Lohse
Nature biotechnology 21 (7), 807-812, 2003
5312003
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
4742021
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ...
Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017
4202017
Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling
JP Vilardaga, VO Nikolaev, K Lorenz, S Ferrandon, Z Zhuang, MJ Lohse
Nature chemical biology 4 (2), 126-131, 2008
3122008
Retromer terminates the generation of cAMP by internalized PTH receptors
TN Feinstein, VL Wehbi, JA Ardura, DS Wheeler, S Ferrandon, ...
Nature chemical biology 7 (5), 278-284, 2011
2452011
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin
TN Feinstein, N Yui, MJ Webber, VL Wehbi, HP Stevenson, JD King, ...
Journal of Biological Chemistry 288 (39), 27849-27860, 2013
2402013
Endosomal generation of cAMP in GPCR signaling
JP Vilardaga, FG Jean-Alphonse, TJ Gardella
Nature chemical biology 10 (9), 700-706, 2014
2332014
Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor
T Dean, JP Vilardaga, JT Potts Jr, TJ Gardella
Molecular endocrinology 22 (1), 156-166, 2008
2312008
PTH receptor-1 signalling—mechanistic insights and therapeutic prospects
RW Cheloha, SH Gellman, JP Vilardaga, TJ Gardella
Nature Reviews Endocrinology 11 (12), 712-724, 2015
2252015
Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism
M Castro, VO Nikolaev, D Palm, MJ Lohse, JP Vilardaga
Proceedings of the National Academy of Sciences 102 (44), 16084-16089, 2005
2042005
Structure and dynamics of the active human parathyroid hormone receptor-1
LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ...
Science 364 (6436), 148-153, 2019
2022019
Molecular basis of inverse agonism in a G protein–coupled receptor
JP Vilardaga, R Steinmeyer, GS Harms, MJ Lohse
Nature chemical biology 1 (1), 25-28, 2005
1832005
Real-time optical recording of β1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol
F Rochais, JP Vilardaga, VO Nikolaev, M Bünemann, MJ Lohse, ...
The Journal of clinical investigation 117 (1), 229-235, 2007
1812007
Noncanonical GPCR signaling arising from a PTH receptor–arrestin–Gβγ complex
VL Wehbi, HP Stevenson, TN Feinstein, G Calero, G Romero, ...
Proceedings of the National Academy of Sciences 110 (4), 1530-1535, 2013
1802013
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation
M Okazaki, S Ferrandon, JP Vilardaga, ML Bouxsein, JT Potts Jr, ...
Proceedings of the National Academy of Sciences 105 (43), 16525-16530, 2008
1692008
Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm
JP Vilardaga, G Romero, PA Friedman, TJ Gardella
Cellular and Molecular Life Sciences 68, 1-13, 2011
1592011
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors
MJ Lohse, VO Nikolaev, P Hein, C Hoffmann, JP Vilardaga, M Bünemann
Trends in pharmacological sciences 29 (3), 159-165, 2008
1572008
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