USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis YH Fan, J Cheng, SA Vasudevan, J Dou, H Zhang, RH Patel, IT Ma, ... Cell death & disease 4 (10), e867-e867, 2013 | 207 | 2013 |
Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design JL Rokita, KS Rathi, MF Cardenas, KA Upton, J Jayaseelan, KL Cross, ... Cell reports 29 (6), 1675-1689. e9, 2019 | 176 | 2019 |
USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase Y Fan, R Mao, Y Yu, S Liu, Z Shi, J Cheng, H Zhang, L An, Y Zhao, X Xu, ... Journal of Experimental Medicine 211 (2), 313-328, 2014 | 172 | 2014 |
A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways J Cheng, YH Fan, X Xu, H Zhang, J Dou, Y Tang, X Zhong, Y Rojas, Y Yu, ... Cell death & disease 5 (2), e1079-e1079, 2014 | 122 | 2014 |
Least cost influence maximization across multiple social networks H Zhang, DT Nguyen, H Zhang, MT Thai IEEE/ACM Transactions On Networking 24 (2), 929-939, 2015 | 103 | 2015 |
Cost-effective viral marketing for time-critical campaigns in large-scale social networks TN Dinh, H Zhang, DT Nguyen, MT Thai IEEE/acm Transactions on Networking 22 (6), 2001-2011, 2013 | 102 | 2013 |
Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma L Huang, S Garrett Injac, K Cui, F Braun, Q Lin, Y Du, H Zhang, M Kogiso, ... Science translational medicine 10 (464), eaat0150, 2018 | 69 | 2018 |
Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis Y Wang, L Wang, S Guan, W Cao, H Wang, Z Chen, Y Zhao, Y Yu, ... Scientific reports 6 (1), 19423, 2016 | 64 | 2016 |
mTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling H Zhang, J Dou, Y Yu, Y Zhao, Y Fan, J Cheng, X Xu, W Liu, S Guan, ... Apoptosis 20, 50-62, 2015 | 62 | 2015 |
The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model J Lu, S Guan, Y Zhao, Y Yu, SE Woodfield, H Zhang, KL Yang, ... Cancer letters 400, 61-68, 2017 | 47 | 2017 |
Wip1 inhibitor GSK2830371 inhibits neuroblastoma growth by inducing Chk2/p53-mediated apoptosis Z Chen, L Wang, D Yao, T Yang, WM Cao, J Dou, JC Pang, S Guan, ... Scientific reports 6 (1), 38011, 2016 | 44 | 2016 |
Amplification and over‐expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells Y Fan, N Ge, X Wang, W Sun, R Mao, W Bu, CJ Creighton, P Zheng, ... The Journal of pathology 232 (1), 75-86, 2014 | 38 | 2014 |
Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling S Bieerkehazhi, Z Chen, Y Zhao, Y Yu, H Zhang, SA Vasudevan, ... Oncotarget 8 (1), 1469, 2016 | 35 | 2016 |
TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells Z Wang, H Zhang, M Shi, Y Yu, H Wang, WM Cao, Y Zhao, H Zhang Scientific reports 6 (1), 32737, 2016 | 35 | 2016 |
Concurrent inhibition of neurosphere and monolayer cells of pediatric glioblastoma by Aurora A inhibitor MLN8237 predicted survival extension in PDOX models M Kogiso, L Qi, FK Braun, SG Injac, L Zhang, Y Du, H Zhang, FY Lin, ... Clinical Cancer Research 24 (9), 2159-2170, 2018 | 31 | 2018 |
Patient-derived orthotopic xenograft (PDOX) mouse models of primary and recurrent meningioma H Zhang, L Qi, Y Du, LF Huang, FK Braun, M Kogiso, Y Zhao, C Li, ... Cancers 12 (6), 1478, 2020 | 30 | 2020 |
Novel multi-targeted ErbB family inhibitor afatinib blocks EGF-induced signaling and induces apoptosis in neuroblastoma X Mao, Z Chen, Y Zhao, Y Yu, S Guan, SE Woodfield, SA Vasudevan, ... Oncotarget 8 (1), 1555, 2016 | 29 | 2016 |
Xenotransplantation of pediatric low grade gliomas confirms the enrichment of BRAF V600E mutation and preservation of CDKN2A deletion in a novel orthotopic xenograft mouse … M Kogiso, L Qi, H Lindsay, Y Huang, X Zhao, Z Liu, FK Braun, Y Du, ... Oncotarget 8 (50), 87455, 2017 | 27 | 2017 |
TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis S Guan, J Lu, Y Zhao, SE Woodfield, H Zhang, X Xu, Y Yu, J Zhao, ... Oncotarget 8 (20), 33666, 2017 | 24 | 2017 |
Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo H Li, Y Wang, Z Chen, J Lu, J Pan, Y Yu, Y Zhao, H Zhang, T Hu, Q Liu, ... Oncotarget 8 (4), 5874, 2016 | 23 | 2016 |