Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups F Delahaye, C Breton, PY Risold, M Enache, I Dutriez-Casteloot, ... Endocrinology 149 (2), 470-475, 2008 | 322 | 2008 |
Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice K Mao, GF Quipildor, T Tabrizian, A Novaj, F Guan, RO Walters, ... Nature communications 9 (1), 2394, 2018 | 144 | 2018 |
Maternal prenatal undernutrition alters the response of POMC neurons to energy status variation in adult male rat offspring C Breton, MA Lukaszewski, PY Risold, M Enache, J Guillemot, G Riviere, ... American Journal of Physiology-Endocrinology and Metabolism 296 (3), E462-E472, 2009 | 117 | 2009 |
Maternal prenatal undernutrition programs adipose tissue gene expression in adult male rat offspring under high-fat diet MA Lukaszewski, S Mayeur, I Fajardy, F Delahaye, I Dutriez-Casteloot, ... American Journal of Physiology-Endocrinology and Metabolism 301 (3), E548-E559, 2011 | 78 | 2011 |
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes N Pervjakova, GH Moen, MC Borges, T Ferreira, JP Cook, C Allard, ... Human Molecular Genetics 31 (19), 3377-3391, 2022 | 70 | 2022 |
Genetic variants influence on the placenta regulatory landscape F Delahaye, C Do, Y Kong, R Ashkar, M Salas, B Tycko, R Wapner, ... PLoS genetics 14 (11), e1007785, 2018 | 68 | 2018 |
A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets NA Wijetunga, M Pascual, J Tozour, F Delahaye, M Alani, M Adeyeye, ... Oncogene 36 (14), 2030-2044, 2017 | 48 | 2017 |
Maternal perinatal undernutrition programs a “brown-like” phenotype of gonadal white fat in male rat at weaning F Delahaye, MA Lukaszewski, JS Wattez, O Cisse, I Dutriez-Casteloot, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 47 | 2010 |
The meta-epigenomic structure of purified human stem cell populations is defined at cis-regulatory sequences NA Wijetunga, F Delahaye, YM Zhao, A Golden, JC Mar, FH Einstein, ... Nature communications 5 (1), 5195, 2014 | 43 | 2014 |
Sexual dimorphism in epigenomic responses of stem cells to extreme fetal growth F Delahaye, NA Wijetunga, HJ Heo, JN Tozour, YM Zhao, JM Greally, ... Nature communications 5 (1), 5187, 2014 | 43 | 2014 |
DNA methylation loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases F Tekola-Ayele, X Zeng, M Ouidir, T Workalemahu, C Zhang, F Delahaye, ... Clinical Epigenetics 12, 1-14, 2020 | 40 | 2020 |
The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects E Lambert, O Saha, B Soares Landeira, AR Melo de Farias, X Hermant, ... Acta Neuropathologica Communications 10 (1), 4, 2022 | 38 | 2022 |
Short-and long-term effects of maternal perinatal undernutrition are lowered by cross-fostering during lactation in the male rat JS Wattez, F Delahaye, LF Barella, A Dickes-Coopman, V Montel, ... Journal of developmental origins of health and disease 5 (2), 109-120, 2014 | 30 | 2014 |
Perinatal nutrition programs the hypothalamic melanocortin system in offspring JS Wattez, F Delahaye, MA Lukaszewski, PY Risold, D Eberlé, D Vieau, ... Hormone and Metabolic Research 45 (13), 980-990, 2013 | 28 | 2013 |
SMITE: an R/Bioconductor package that identifies network modules by integrating genomic and epigenomic information NA Wijetunga, AD Johnston, R Maekawa, F Delahaye, N Ulahannan, ... BMC bioinformatics 18, 1-13, 2017 | 27 | 2017 |
Epigenome-wide association study reveals methylation loci associated with offspring gestational diabetes mellitus exposure and maternal methylome M Canouil, A Khamis, E Keikkala, S Hummel, S Lobbens, A Bonnefond, ... Diabetes Care 44 (9), 1992-1999, 2021 | 23 | 2021 |
T cell receptor and IL-2 signaling strength control memory CD8+ T cell functional fitness via chromatin remodeling SS Chin, E Guillen, L Chorro, S Achar, K Ng, S Oberle, F Alfei, D Zehn, ... Nature communications 13 (1), 2240, 2022 | 21 | 2022 |
Advanced aging phenotype is revealed by epigenetic modifications in rat liver after in utero malnutrition HJ Heo, JN Tozour, F Delahaye, Y Zhao, L Cui, N Barzilai, FH Einstein Aging Cell 15 (5), 964-972, 2016 | 20 | 2016 |
DNA hypermethylation of CD3+ T cells from cord blood of infants exposed to intrauterine growth restriction L Williams, Y Seki, F Delahaye, A Cheng, M Fuloria, F Hughes Einstein, ... Diabetologia 59, 1714-1723, 2016 | 20 | 2016 |
Effect of diet in females (F1) from prenatally undernourished mothers on metabolism and liver function in the F2 progeny is sex-specific O Cissé, I Fajardy, F Delahaye, A Dickes, V Montel, E Moitrot, C Breton, ... European journal of nutrition 58, 2411-2423, 2019 | 14 | 2019 |