Copper (II) complexes with naringenin and hesperetin: cytotoxic activity against A 549 human lung adenocarcinoma cells and investigation on the mode of action LV Tamayo, LR Gouvea, AC Sousa, RM Albuquerque, SF Teixeira, ... Biometals 29, 39-52, 2016 | 138 | 2016 |
Blockade of MIF–CD74 signalling on macrophages and dendritic cells restores the antitumour immune response against metastatic melanoma CR Figueiredo, RA Azevedo, S Mousdell, PT Resende-Lara, L Ireland, ... Frontiers in immunology 9, 1132, 2018 | 136 | 2018 |
Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development CR Figueiredo, H Kalirai, JJ Sacco, RA Azevedo, A Duckworth, ... The Journal of Pathology 250 (4), 420-439, 2020 | 120 | 2020 |
Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo N GIROLA, CR FIGUEIREDO, CF , FARIAS, RA AZEVEDO, ... Biochem Biophys Res Commun 467 (4), 928-934, 2015 | 111 | 2015 |
Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo RA DE AZEVEDO, CR FIGUEIREDO, AK FERREIRA, AL MATSUO, ... Peptides 68, 113–119, 2015 | 80 | 2015 |
ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer RCE Hsieh, S Krishnan, RC Wu, AR Boda, A Liu, M Winkler, WH Hsu, ... Science immunology 7 (72), eabl9330, 2022 | 79 | 2022 |
Apoptotic effect of eugenol envolves g2/m phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro JP LUIZ DE SÁ, AD CÂMARA, D, AS COSTA, JLM RUIZ, D LEVY, ... Phytomedicine 23, 725 - 735, 2016 | 66 | 2016 |
MIF inhibition as a strategy for overcoming resistance to immune checkpoint blockade therapy in melanoma RA de Azevedo, E Shoshan, S Whang, G Markel, AR Jaiswal, A Liu, ... Oncoimmunology 9 (1), 1846915, 2020 | 62 | 2020 |
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast … PL de-Sá-Júnior, KFM Pasqualoto, AK Ferreira, MT Tavares, ... Toxicology and applied pharmacology 266 (3), 385-398, 2013 | 52 | 2013 |
Dillapiole as antileishmanial agent: discovery, cytotoxic activity and preliminary SAR studies of dillapiole analogues R Parise‐Filho, KFM Pasqualoto, FMM Magri, AK Ferreira, BAVG da Silva, ... Archiv Der Pharmazie 345 (12), 934-944, 2012 | 47 | 2012 |
Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the … AK Ferreira, PL de-Sá-Júnior, KFM Pasqualoto, RA de Azevedo, ... Biochimie 99, 195-207, 2014 | 42 | 2014 |
Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo CR Figueiredo, AL Matsuo, FV Pereira, AN Rabaca, CF Farias, N Girola, ... Pharmacognosy magazine 10 (Suppl 2), S363, 2014 | 38 | 2014 |
A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo CR Figueiredo, AL Matsuo, RA Azevedo, MH Massaoka, N Girola, ... Scientific reports 5 (1), 14310, 2015 | 31 | 2015 |
Antitumor Effect of Cationic INKKI Peptide from Bovine β-Casein on Melanoma B16F10 RA Azevedo, AK Ferreira, AVV Auada, KFM Pasqualoto, R Marques-Porto, ... Scientific Research Publishing, 2012 | 31 | 2012 |
Designing and exploring active N′-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients F Palace-Berl, KFM Pasqualoto, SD Jorge, B Zingales, RR Zorzi, MN Silva, ... European journal of medicinal chemistry 96, 330-339, 2015 | 29 | 2015 |
Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice CR Figueiredo, AL Matsuo, MH Massaoka, N Girola, RA Azevedo, ... Advanced pharmaceutical bulletin 4 (Suppl 1), 429, 2014 | 28 | 2014 |
Neolignans isolated from Nectandra leucantha induce apoptosis in melanoma cells by disturbance in mitochondrial integrity and redox homeostasis FS de Sousa, SS Grecco, N Girola, RA Azevedo, CR Figueiredo, ... Phytochemistry 140, 108-117, 2017 | 26 | 2017 |
Novel Capsaicin Analogues as Potential Anticancer Agents: Synthesis, Biological Evaluation, and In Silico Approach MC Damião, KFM Pasqualoto, AK Ferreira, SF Teixeira, RA Azevedo, ... Archiv der Pharmazie 347 (12), 885-895, 2014 | 25 | 2014 |
RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model AK Ferreira, MT Tavares, KFM Pasqualoto, RA de Azevedo, SF Teixeira, ... Tumor Biology 36, 7251-7267, 2015 | 24 | 2015 |
Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling GJV Pereira, MT Tavares, RA Azevedo, BB Martins, MR Cunha, ... Bioorganic & medicinal chemistry 27 (13), 2893-2904, 2019 | 23 | 2019 |