C9orf72 expansion disrupts ATM-mediated chromosomal break repair C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ... Nature neuroscience 20 (9), 1225-1235, 2017 | 185 | 2017 |
Further characterisation of the LPS model of Parkinson’s disease: a comparison of intra-nigral and intra-striatal lipopolysaccharide administration on motor function … DB Hoban, E Connaughton, C Connaughton, G Hogan, C Thornton, ... Brain, behavior, and immunity 27, 91-100, 2013 | 123 | 2013 |
Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone P Mulcahy, A O'doherty, A Paucard, T O'brien, D Kirik, E Dowd Neuroscience 203, 170-179, 2012 | 68 | 2012 |
Characterisation of a novel model of Parkinson's disease by intra-striatal infusion of the pesticide rotenone P Mulcahy, S Walsh, A Paucard, K Rea, E Dowd Neuroscience 181, 234-242, 2011 | 56 | 2011 |
Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits S Herranz-Martin, J Chandran, K Lewis, P Mulcahy, A Higginbottom, ... Disease models & mechanisms 10 (7), 859-868, 2017 | 50 | 2017 |
The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats P Mulcahy, A O’Doherty, A Paucard, T O’Brien, D Kirik, E Dowd Behavioural brain research 243, 6-15, 2013 | 38 | 2013 |
C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten MJ Stopford, A Higginbottom, GM Hautbergue, J Cooper-Knock, ... Human molecular genetics 26 (6), 1133-1145, 2017 | 35 | 2017 |
Gene therapy: a promising approach to treating spinal muscular atrophy PJ Mulcahy, K Iremonger, E Karyka, S Herranz-Martin, KT Shum, ... Human gene therapy 25 (7), 575-586, 2014 | 23 | 2014 |
Adeno-associated vectors for gene delivery to the nervous system PJ Mulcahy, C Binny, B Muszynski, E Karyka, M Azzouz Gene delivery and therapy for neurological disorders, 1-22, 2015 | 4 | 2015 |
A biomaterials approach to modulate striatal toxicity of gene vectors: A comparative study B Newland, T Moloney, P Mulcahy, E Dowd, A Pandit MOVEMENT DISORDERS 27, S148-S148, 2012 | | 2012 |
Development and characterisation of a novel model of Parkinson's disease by sequential intra-nigral administration of AAV-alpha-synuclein and the pesticide, rotenone, in the rat PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd MOVEMENT DISORDERS 27, S491-S491, 2012 | | 2012 |
Modelling Parkinson's disease by chronic systemic exposure of? alpha-synuclein overexpressing rats to the pesticide, rotenone PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd MOVEMENT DISORDERS 27, S491-S491, 2012 | | 2012 |
Development of a dual-hit model of Parkinson's disease by PJ Mulcahy Neuroscience 181, 234-242, 2012 | | 2012 |
Systemic Rotenone Does Not Enhance Parkinsonian Pathology Caused By Intracerebral Alpha-Synuclein In Rats PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd Irish Journal of Medical Science 180, 20, 2011 | | 2011 |
INTRACEREBRAL INFUSION OF ROTENONE INTO THE STRIATUM OR SUBSTANTIA NIGRA CAUSES BEHAVIOURAL DEFICITS AND NIGROSTRIATAL DEGENERATION ASSOCIATED WITH PARKINSON'S DISEASE PJ Mulcahy, A Paucard, S Walsh, E Dowd IRISH JOURNAL OF MEDICAL SCIENCE 179, S127-S128, 2010 | | 2010 |