Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors AA Estrada, X Liu, C Baker-Glenn, A Beresford, DJ Burdick, M Chambers, ... Journal of medicinal chemistry 55 (22), 9416-9433, 2012 | 167 | 2012 |
Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors AA Estrada, BK Chan, C Baker-Glenn, A Beresford, DJ Burdick, ... Journal of medicinal chemistry 57 (3), 921-936, 2014 | 141 | 2014 |
Total Synthesis of (−)‐Ulapualide A: The Danger of Overdependence on NMR Spectroscopy in Assignment of Stereochemistry G Pattenden, NJ Ashweek, CAG Baker‐Glenn, GM Walker, JGK Yee Angewandte Chemie International Edition 46 (23), 4359-4363, 2007 | 58 | 2007 |
Discovery of a highly selective, brain-penetrant aminopyrazole LRRK2 inhibitor BK Chan, AA Estrada, H Chen, J Atherall, C Baker-Glenn, A Beresford, ... ACS medicinal chemistry letters 4 (1), 85-90, 2013 | 53 | 2013 |
A catalytic asymmetric bioorganic route to enantioenriched tetrahydro-and dihydropyranones C Baker-Glenn, N Hodnett, M Reiter, S Ropp, R Ancliff, V Gouverneur Journal of the American Chemical Society 127 (5), 1481-1486, 2005 | 47 | 2005 |
Total synthesis of (−)-ulapualide A, a novel tris-oxazole macrolide from marine nudibranchs, based on some biosynthesis speculation G Pattenden, NJ Ashweek, CAG Baker-Glenn, J Kempson, GM Walker, ... Organic & Biomolecular Chemistry 6 (8), 1478-1497, 2008 | 41 | 2008 |
Alkene synthesis: elimination of arenesulfinic acid from alkyl aryl sulfones using potassium trimethylsilanolate as base CAG Baker-Glenn, AGM Barrett, AA Gray, PA Procopiou, M Ruston Tetrahedron letters 46 (43), 7427-7430, 2005 | 33 | 2005 |
Developing inhaled drugs for respiratory diseases: a medicinal chemistry perspective E Pasqua, N Hamblin, C Edwards, C Baker-Glenn, C Hurley Drug Discovery Today 27 (1), 134-150, 2022 | 31 | 2022 |
Pyrazole aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, DJ Burdick, M Chambers, BK Chan, H Chen, A Estrada, ... US Patent 8,815,882, 2014 | 31 | 2014 |
Effects of ulapualide A and synthetic macrolide analogues on actin dynamics and gene regulation E Vincent, J Saxton, C Baker-Glenn, I Moal, JD Hirst, G Pattenden, ... Cellular and molecular life sciences 64, 487-497, 2007 | 22 | 2007 |
Aminopyrimidine derivatives as LRRK2 inhibitors C Baker-Glenn, DJ Burdick, M Chambers, BK Chan, H Chen, A Estrada, ... US Patent 8,354,420, 2013 | 21 | 2013 |
Mapping the structural requirements of inducers and substrates for decarboxylation of weak acid preservatives by the food spoilage mould Aspergillus niger M Stratford, A Plumridge, MW Pleasants, M Novodvorska, ... International Journal of Food Microbiology 157 (3), 375-383, 2012 | 21 | 2012 |
Pyrazole aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, DJ Burdick, BK Chan, M Chambers, H Chen, A Estrada, ... US Patent 9,212,173, 2015 | 17 | 2015 |
Aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, M Chambers, BK Chan, A Estrada, D Shore, ZK Sweeney, ... US Patent 9,145,402, 2015 | 17 | 2015 |
Aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, M Chambers, BK Chan, A Estrada, ZK Sweeney US Patent 8,791,130, 2014 | 17 | 2014 |
Aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, DJ Burdick, M Chambers, BK Chan, H Chen, A Estrada, ... US Patent 8,809,331, 2014 | 12 | 2014 |
Aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, DJ Burdick, M Chambers, BK Chan, H Chen, A Estrada, ... US Patent 8,802,674, 2014 | 12 | 2014 |
A biocatalytic route to enantioenriched, sulfanyl aldol products C Baker-Glenn, R Ancliff, V Gouverneur Tetrahedron 60 (35), 7607-7619, 2004 | 12 | 2004 |
Aminopyrimidine derivatives as LRRK2 modulators C Baker-Glenn, M Chambers, BK Chan, A Estrada, ZK Sweeney US Patent 8,796,296, 2014 | 11 | 2014 |
Inhibitors of PDE4 enzyme and antagonists of muscarinic M3 receptor E Armani, G Amari, M Riccaboni, C Baker-Glenn US Patent 9,169,245, 2015 | 10 | 2015 |