| Endothelial cell infection and endotheliitis in COVID-19 Z Varga, AJ Flammer, P Steiger, M Haberecker, R Andermatt, ... The Lancet 395 (10234), 1417-1418, 2020 | 7212 | 2020 |
| Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs) C Peyssonnaux, AS Zinkernagel, RA Schuepbach, E Rankin, S Vaulont, ... The Journal of clinical investigation 117 (7), 1926-1932, 2007 | 824 | 2007 |
| Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases DM Heuberger, RA Schuepbach Thrombosis journal 17 (1), 4, 2019 | 304 | 2019 |
| Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19 … PDW Garcia, T Fumeaux, P Guerci, DM Heuberger, J Montomoli, ... EClinicalMedicine 25, 2020 | 245 | 2020 |
| Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice H Frebel, V Nindl, RA Schuepbach, T Braunschweiler, K Richter, J Vogel, ... Journal of Experimental Medicine 209 (13), 2485-2499, 2012 | 212 | 2012 |
| Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells C Feistritzer, RA Schuepbach, LO Mosnier, LA Bush, E Di Cera, JH Griffin, ... Journal of Biological Chemistry 281 (29), 20077-20084, 2006 | 156 | 2006 |
| Severe coronavirus disease 2019 (COVID-19) is associated with elevated serum immunoglobulin (Ig) A and antiphospholipid IgA antibodies O Hasan Ali, D Bomze, L Risch, SD Brugger, M Paprotny, M Weber, ... Clinical Infectious Diseases 73 (9), e2869-e2874, 2021 | 112 | 2021 |
| Pharmacologic augmentation of hypoxia-inducible factor—1α with mimosine boosts the bactericidal capacity of phagocytes AS Zinkernagel, C Peyssonnaux, RS Johnson, V Nizet The Journal of infectious diseases 197 (2), 214-217, 2008 | 109 | 2008 |
| SARS-CoV-2 leads to a small vessel endotheliitis in the heart U Maccio, AS Zinkernagel, SM Shambat, X Zeng, G Cathomas, ... EBioMedicine 63, 2021 | 104 | 2021 |
| Clindamycin affects group A Streptococcus virulence factors and improves clinical outcome F Andreoni, C Zürcher, A Tarnutzer, K Schilcher, A Neff, N Keller, ... The Journal of infectious diseases 215 (2), 269-277, 2017 | 102 | 2017 |
| Bacterial pulmonary superinfections are associated with longer duration of ventilation in critically ill COVID-19 patients PK Buehler, AS Zinkernagel, DA Hofmaenner, PDW Garcia, CT Acevedo, ... Cell Reports Medicine 2 (4), 2021 | 100 | 2021 |
| Protease‐activated receptor‐1 cleaved at R46 mediates cytoprotective effects RA Schuepbach, J Madon, M Ender, P Galli, M Riewald Journal of Thrombosis and Haemostasis 10 (8), 1675-1684, 2012 | 97 | 2012 |
| DNase Sda1 Allows Invasive M1T1 Group A Streptococcus to Prevent TLR9-Dependent Recognition S Uchiyama, F Andreoni, RA Schuepbach, V Nizet, AS Zinkernagel PLoS pathogens 8 (6), e1002736, 2012 | 96 | 2012 |
| Model of end stage liver disease (MELD) score greater than 23 predicts length of stay in the ICU but not mortality in liver transplant recipients CE Oberkofler, P Dutkowski, R Stocker, RA Schuepbach, JF Stover, ... Critical Care 14, 1-10, 2010 | 91 | 2010 |
| Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1 RA Schuepbach, C Feistritzer, JA Fernández, JH Griffin, M Riewald Thrombosis and haemostasis 101 (04), 724-733, 2009 | 91 | 2009 |
| Nonstable Staphylococcus aureus Small-Colony Variants Are Induced by Low pH and Sensitized to Antimicrobial Therapy by Phagolysosomal Alkalinization N Leimer, C Rachmühl, M Palheiros Marques, AS Bahlmann, A Furrer, ... The Journal of infectious diseases 213 (2), 305-313, 2016 | 84 | 2016 |
| Outcome of extracorporeal membrane oxygenation as a bridge to lung transplantation: an institutional experience and literature review I Inci, S Klinzing, D Schneiter, RA Schuepbach, P Kestenholz, S Hillinger, ... Transplantation 99 (8), 1667-1671, 2015 | 84 | 2015 |
| Hyperantithrombotic, noncytoprotective Glu149Ala-activated protein C mutant LO Mosnier, A Zampolli, EJ Kerschen, RA Schuepbach, Y Banerjee, ... Blood, The Journal of the American Society of Hematology 113 (23), 5970-5978, 2009 | 81 | 2009 |
| Artificial liver support with the molecular adsorbent recirculating system: activation of coagulation and bleeding complications EB Bachli, RA Schuepbach, M Maggiorini, R Stocker, B Müllhaupt, ... Liver International 27 (4), 475-484, 2007 | 77 | 2007 |
| Coagulation factor Xa cleaves protease‐activated receptor‐1 and mediates signaling dependent on binding to the endothelial protein C receptor RA Schuepbach, M Riewald Journal of Thrombosis and Haemostasis 8 (2), 379-388, 2010 | 76 | 2010 |
