Candida albicans triggers NLRP3-mediated pyroptosis in macrophages M Wellington, K Koselny, FS Sutterwala, DJ Krysan Eukaryotic cell 13 (2), 329-340, 2014 | 232 | 2014 |
A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole BD Harrison, J Hashemi, M Bibi, R Pulver, D Bavli, Y Nahmias, ... PLoS biology 12 (3), e1001815, 2014 | 183 | 2014 |
New facets of antifungal therapy YL Chang, SJ Yu, J Heitman, M Wellington, YL Chen Virulence 8 (2), 222-236, 2017 | 173 | 2017 |
Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization K Dolan, S Montgomery, B Buchheit, L DiDone, M Wellington, DJ Krysan Antimicrobial agents and chemotherapy 53 (8), 3337-3346, 2009 | 135 | 2009 |
Live Candida albicans Suppresses Production of Reactive Oxygen Species in Phagocytes M Wellington, K Dolan, DJ Krysan Infection and immunity 77 (1), 405-413, 2009 | 116 | 2009 |
A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the … A Butts, L DiDone, K Koselny, BK Baxter, Y Chabrier-Rosello, ... Eukaryotic Cell 12 (2), 278-287, 2013 | 101 | 2013 |
Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo A Butts, K Koselny, Y Chabrier-Roselló, CP Semighini, JCS Brown, ... MBio 5 (1), 10.1128/mbio. 00765-13, 2014 | 96 | 2014 |
Catching Fire: Candida albicans, Macrophages, and Pyroptosis DJ Krysan, FS Sutterwala, M Wellington PLoS pathogens 10 (6), e1004139, 2014 | 94 | 2014 |
The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis K Koselny, J Green, L DiDone, JP Halterman, AW Fothergill, ... Antimicrobial agents and chemotherapy 60 (12), 7115-7127, 2016 | 80 | 2016 |
The Spx regulator modulates stress responses and virulence in Enterococcus faecalis JK Kajfasz, JE Mendoza, AO Gaca, JH Miller, KA Koselny, ... Infection and immunity 80 (7), 2265-2275, 2012 | 76 | 2012 |
5‐Fluoro‐orotic acid induces chromosome alterations in Candida albicans M Wellington, E Rustchenko Yeast 22 (1), 57-70, 2005 | 69 | 2005 |
Candida albicans morphogenesis is not required for macrophage interleukin 1β production M Wellington, K Koselny, DJ Krysan MBio 4 (1), 10.1128/mbio. 00433-12, 2013 | 68 | 2013 |
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... MBio 9 (4), 10.1128/mbio. 01581-18, 2018 | 66 | 2018 |
Nitrite Reductase NirS Is Required for Type III Secretion System Expression and Virulence in the Human Monocyte Cell Line THP-1 by Pseudomonas aeruginosa NE Van Alst, M Wellington, VL Clark, CG Haidaris, BH Iglewski Infection and immunity 77 (10), 4446-4454, 2009 | 62 | 2009 |
A genome-wide screen of deletion mutants in the filamentous Saccharomyces cerevisiae background identifies ergosterol as a direct trigger of macrophage pyroptosis K Koselny, N Mutlu, AY Minard, A Kumar, DJ Krysan, M Wellington MBio 9 (4), 10.1128/mbio. 01204-18, 2018 | 54 | 2018 |
Overcoming fungal echinocandin resistance through inhibition of the non-essential stress kinase Yck2 T Caplan, Á Lorente-Macías, PJ Stogios, E Evdokimova, S Hyde, ... Cell chemical biology 27 (3), 269-282. e5, 2020 | 52 | 2020 |
Antifungal pharmacotherapy for neonatal candidiasis JM Bliss, M Wellington, F Gigliotti Seminars in perinatology 27 (5), 365-374, 2003 | 48 | 2003 |
Enhanced Phagocytosis of Candida Species Mediated by Opsonization with a Recombinant Human Antibody Single-Chain Variable Fragment M Wellington, JM Bliss, CG Haidaris Infection and immunity 71 (12), 7228-7231, 2003 | 37 | 2003 |
5-fluoro-orotic acid induces chromosome alterations in genetically manipulated strains of Candida albicans M Wellington, M Anaul, KE Rustchenko Mycologia 98 (3), 393-398, 2006 | 33 | 2006 |
Role of the 14–3–3 protein in carbon metabolism of the pathogenic yeast Candida albicans YK Wang, B Das, DH Huber, M Wellington, MA Kabir, F Sherman, ... Yeast 21 (8), 685-702, 2004 | 31 | 2004 |