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L. A. Liggett
L. A. Liggett
其他姓名Alex Liggett, Alexander Liggett
Postdoctoral Fellow at Harvard Medical School, The Broad Institute, and Boston Children's
在 broadinstitute.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Trisomy 21 consistently activates the interferon response
KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ...
Elife 5, e16220, 2016
2672016
Unraveling hematopoiesis through the lens of genomics
LA Liggett, VG Sankaran
Cell 182 (6), 1384-1400, 2020
1312020
The burden of trisomy 21 disrupts the proteostasis network in Down syndrome
S Aivazidis, CM Coughlan, AK Rauniyar, H Jiang, LA Liggett, KN Maclean, ...
PloS one 12 (4), e0176307, 2017
642017
Changing mutational and adaptive landscapes and the genesis of cancer
LA Liggett, J DeGregori
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1867 (2), 84-94, 2017
492017
Variant to function mapping at single-cell resolution through network propagation
F Yu, LD Cato, C Weng, LA Liggett, S Jeon, K Xu, CWK Chiang, ...
Nature Biotechnology 40 (11), 1644-1653, 2022
352022
Clonal hematopoiesis in sickle cell disease
LA Liggett, LD Cato, JS Weinstock, Y Zhang, SM Nouraie, MT Gladwin, ...
The Journal of Clinical Investigation 132 (4), 2022
292022
Deciphering cell states and genealogies of human haematopoiesis
C Weng, F Yu, D Yang, M Poeschla, LA Liggett, MG Jones, X Qiu, ...
Nature 627 (8003), 389-398, 2024
182024
Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation
LA Liggett, MD Galbraith, KP Smith, KD Sullivan, RE Granrath, ...
Blood Advances 5 (7), 1791-1796, 2021
142021
FERMI: a novel method for sensitive detection of rare mutations in somatic tissue
LA Liggett, A Sharma, S De, J DeGregori
G3: Genes, Genomes, Genetics 9 (9), 2977-2987, 2019
102019
Trisomy 21 consistently activates the interferon response. Elife 5
KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ...
eLife Sciences Publications Limited 5, 1709, 2016
102016
Optical imaging of targeted β-galactosidase in brain tumors to detect EGFR levels
AM Broome, G Ramamurthy, K Lavik, A Liggett, I Kinstlinger, J Basilion
Bioconjugate chemistry 26 (4), 660-668, 2015
62015
Measuring gender differences in attitudes using the lost-letter technique
L Liggett, C Blair, S Kennison
Journal of Scientific Psychology, 16-24, 2010
42010
Sowing the Seeds of Clonal Hematopoiesis
LA Liggett, RA Voit, VG Sankaran
Cell Stem Cell 27 (2), 195-197, 2020
22020
Conserved patterns of somatic mutations in human peripheral blood cells
LA Liggett, A Sharma, S De, J DeGregori
bioRxiv, 208066, 2017
22017
Patchwork cancer predisposition
LA Liggett, VG Sankaran
Cancer discovery 12 (4), 889-891, 2022
12022
A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution
AI Rozhok, RE Silberman, KC Higa, LA Liggett, A Amon, J DeGregori
Scientific Reports 10 (1), 12198, 2020
2020
Identifying Rare Somatic Mutations as a Means of Understanding Tissue Clonal Evolution
LA Liggett
University of Colorado Denver, Anschutz Medical Campus, 2019
2019
Tumor imaging via β-galactosidase fragment complementation with a multifunctional targeted-reporter complex
AM Broome, K Lavik, G Ramamurthy, LA Liggett, RS Agnes, JP Basilion
Cancer Research 70 (8_Supplement), 4341-4341, 2010
2010
Effects of unloading (HS) and loading (exercise training) on overall work capacity in rats.
F Silva, I Bederman, A Liggett, M Cabrera
The FASEB Journal 22, 121-121, 2008
2008
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