MicroRNA-7a regulates pancreatic β cell function M Latreille, J Hausser, I Stützer, Q Zhang, B Hastoy, S Gargani, ... The Journal of clinical investigation 124 (6), 2722-2735, 2014 | 326 | 2014 |
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation M Shigeto, R Ramracheya, AI Tarasov, CY Cha, MV Chibalina, B Hastoy, ... The Journal of clinical investigation 125 (12), 4714-4728, 2015 | 178 | 2015 |
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion G Gheni, M Ogura, M Iwasaki, N Yokoi, K Minami, Y Nakayama, K Harada, ... Cell reports 9 (2), 661-673, 2014 | 170 | 2014 |
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion E Vergari, JG Knudsen, R Ramracheya, A Salehi, Q Zhang, J Adam, ... Nature communications 10 (1), 139, 2019 | 165 | 2019 |
The β-cell assassin: IAPP cytotoxicity D Raleigh, X Zhang, B Hastoy, A Clark Journal of molecular endocrinology 59 (3), R121-R140, 2017 | 136 | 2017 |
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion OP Dwivedi, M Lehtovirta, B Hastoy, V Chandra, NAJ Krentz, S Kleiner, ... Nature genetics 51 (11), 1596-1606, 2019 | 123 | 2019 |
RFX6 regulates insulin secretion by modulating Ca2+ homeostasis in human β cells V Chandra, O Albagli-Curiel, B Hastoy, J Piccand, C Randriamampita, ... Cell reports 9 (6), 2206-2218, 2014 | 100 | 2014 |
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics J Ast, A Arvaniti, NHF Fine, D Nasteska, FB Ashford, Z Stamataki, ... Nature Communications 11 (1), 467, 2020 | 99 | 2020 |
Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells SK Thomsen, A Raimondo, B Hastoy, S Sengupta, XQ Dai, A Bautista, ... Nature genetics 50 (8), 1122-1131, 2018 | 77 | 2018 |
AP2σ mutations impair calcium-sensing receptor trafficking and signaling, and show an endosomal pathway to spatially direct G-protein selectivity CM Gorvin, A Rogers, B Hastoy, AI Tarasov, M Frost, S Sposini, A Inoue, ... Cell reports 22 (4), 1054-1066, 2018 | 76 | 2018 |
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion SC Collins, HW Do, B Hastoy, A Hugill, J Adam, MV Chibalina, ... Diabetes 65 (7), 1952-1961, 2016 | 65 | 2016 |
Electrophysiological properties of human beta-cell lines EndoC-βH1 and-βH2 conform with human beta-cells B Hastoy, M Godazgar, A Clark, V Nylander, I Spiliotis, M van de Bunt, ... Scientific reports 8 (1), 16994, 2018 | 50 | 2018 |
A central small amino acid in the VAMP2 transmembrane domain regulates the fusion pore in exocytosis B Hastoy, PA Scotti, A Milochau, Z Fezoua-Boubegtiten, J Rodas, ... Scientific reports 7 (1), 2835, 2017 | 30 | 2017 |
NKX6. 1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations SK Gupta, A Wesolowska-Andersen, AK Ringgaard, H Jaiswal, L Song, ... Stem Cell Research 29, 220-231, 2018 | 27 | 2018 |
A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function AK Grotz, F Abaitua, E Navarro-Guerrero, B Hastoy, D Ebner, AL Gloyn Wellcome Open Research 4, 2019 | 24 | 2019 |
Fusion pore in exocytosis: More than an exit gate? A β-cell perspective B Hastoy, A Clark, P Rorsman, J Lang Cell calcium 68, 45-61, 2017 | 20 | 2017 |
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ... Cell reports 34 (5), 2021 | 11 | 2021 |
Tissue-specific alteration of metabolic pathways influences glycemic regulation NHJ Ng, SM Willems, J Fernandez, RS Fine, E Wheeler, J Wessel, ... BioRxiv, 790618, 2019 | 10 | 2019 |
The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment Z Fezoua-Boubegtiten, B Hastoy, P Scotti, A Milochau, K Bathany, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1861 (3), 670-676, 2019 | 10 | 2019 |
Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell identity and function L Lopez-Noriega, R Callingham, A Martinez-Sánchez, S Nawaz, G Pizza, ... BiorXiv, 2020.07. 17.209015, 2020 | 5 | 2020 |