| Hypercapnic Acidosis Is Protective in an In Vivo Model of Ventilator-induced Lung Injury SE Sinclair, DA Kregenow, WJE Lamm, IR Starr, EY Chi, MP Hlastala American journal of respiratory and critical care medicine 166 (3), 403-408, 2002 | 325 | 2002 |
| Hyperoxia in the intensive care unit: why more is not always better WA Altemeier, SE Sinclair Current opinion in critical care 13 (1), 73-78, 2007 | 307 | 2007 |
| Activation and regulation of systemic inflammation in ARDS: rationale for prolonged glucocorticoid therapy GU Meduri, D Annane, GP Chrousos, PE Marik, SE Sinclair Chest 136 (6), 1631-1643, 2009 | 301 | 2009 |
| Cyclic mechanical strain increases reactive oxygen species production in pulmonary epithelial cells KE Chapman, SE Sinclair, D Zhuang, A Hassid, LP Desai, CM Waters American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (5 …, 2005 | 250 | 2005 |
| Augmented lung injury due to interaction between hyperoxia and mechanical ventilation SE Sinclair, WA Altemeier, G Matute-Bello, EY Chi Critical care medicine 32 (12), 2496-2501, 2004 | 250 | 2004 |
| Determination of regional ventilation and perfusion in the lung using xenon and computed tomography TC Kreck, MA Krueger, WA Altemeier, SE Sinclair, HT Robertson, ... Journal of Applied Physiology 91 (4), 1741-1749, 2001 | 97 | 2001 |
| Comparative mutagenic effects of structurally similar flavonoids quercetin and taxifolin on tester strains Salmonella typhimurium TA102 and Escherichia coli WP‐2 uvrA PS Makena, SC Pierce, KT Chung, SE Sinclair Environmental and molecular mutagenesis 50 (6), 451-459, 2009 | 86 | 2009 |
| CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2 MC Ghosh, PS Makena, V Gorantla, SE Sinclair, CM Waters American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (9 …, 2012 | 85 | 2012 |
| Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a MC Ghosh, V Gorantla, PS Makena, C Luellen, SE Sinclair, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 305 (3 …, 2013 | 68 | 2013 |
| Balance of life and death in alveolar epithelial type II cells: proliferation, apoptosis, and the effects of cyclic stretch on wound healing LM Crosby, C Luellen, Z Zhang, LL Tague, SE Sinclair, CM Waters American Journal of Physiology-Lung Cellular and Molecular Physiology 301 (4 …, 2011 | 63 | 2011 |
| Preexposure to hyperoxia causes increased lung injury and epithelial apoptosis in mice ventilated with high tidal volumes PS Makena, CL Luellen, L Balazs, MC Ghosh, K Parthasarathi, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 299 (5 …, 2010 | 61 | 2010 |
| Airway strain during mechanical ventilation in an intact animal model SE Sinclair, RC Molthen, ST Haworth, CA Dawson, CM Waters American journal of respiratory and critical care medicine 176 (8), 786-794, 2007 | 57 | 2007 |
| High tidal volume mechanical ventilation with hyperoxia alters alveolar type II cell adhesion LP Desai, SE Sinclair, KE Chapman, A Hassid, CM Waters American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (3 …, 2007 | 55 | 2007 |
| Hyperoxia alters the mechanical properties of alveolar epithelial cells E Roan, K Wilhelm, A Bada, PS Makena, VK Gorantla, SE Sinclair, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 302 …, 2012 | 47 | 2012 |
| Therapeutic hypercapnia and ventilation-perfusion matching in acute lung injury: low minute ventilation vs inspired CO2 SE Sinclair, DA Kregenow, I Starr, C Schimmel, WJE Lamm, MP Hlastala, ... Chest 130 (1), 85-92, 2006 | 45 | 2006 |
| Exercise alters fractal dimension and spatial correlation of pulmonary blood flow in the horse SE Sinclair, S McKinney, RW Glenny, SL Bernard, MP Hlastala Journal of Applied Physiology 88 (6), 2269-2278, 2000 | 43 | 2000 |
| Regulation and function of the two-pore-domain (K2P) potassium channel Trek-1 in alveolar epithelial cells A Schwingshackl, B Teng, M Ghosh, AN West, P Makena, V Gorantla, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (1 …, 2012 | 40 | 2012 |
| Positive end-expiratory pressure alters the severity and spatial heterogeneity of ventilator-induced lung injury: an argument for cyclical airway collapse SE Sinclair, E Chi, HI Lin, WA Altemeier Journal of critical care 24 (2), 206-211, 2009 | 37 | 2009 |
| Pathophysiology of acute respiratory distress syndrome. Glucocorticoid receptor-mediated regulation of inflammation and response to prolonged glucocorticoid treatment GU Meduri, W Bell, S Sinclair, D Annane La Presse Médicale 40 (12), e543-e560, 2011 | 35 | 2011 |
| Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation PS Makena, VK Gorantla, MC Ghosh, L Bezawada, L Balazs, C Luellen, ... Journal of Applied Physiology 111 (5), 1467-1476, 2011 | 35 | 2011 |
