关注
Gwen R. Buel
Gwen R. Buel
Research Fellow, National Cancer Institute, National Institutes of Health
在 nih.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Nutrient regulation of the mTOR complex 1 signaling pathway
SG Kim, GR Buel, J Blenis
Molecules and cells 35 (6), 463-473, 2013
3022013
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex
SG Kim, GR Hoffman, G Poulogiannis, GR Buel, YJ Jang, KW Lee, ...
Molecular cell 49 (1), 172-185, 2013
2312013
Can AlphaFold2 predict the impact of missense mutations on structure?
GR Buel, KJ Walters
Nature structural & molecular biology 29 (1), 1-2, 2022
2082022
ERK2 mediates metabolic stress response to regulate cell fate
S Shin, GR Buel, L Wolgamott, DR Plas, JM Asara, J Blenis, SO Yoon
Molecular cell 59 (3), 382-398, 2015
1032015
ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1/FoxO1 activation
S Shin, GR Buel, MJ Nagiec, MJ Han, PP Roux, J Blenis, SO Yoon
Proceedings of the National Academy of Sciences 116 (8), 2967-2976, 2019
742019
Focal adhesion-and IGF1R-dependent survival and migratory pathways mediate tumor resistance to mTORC1/2 inhibition
SO Yoon, S Shin, FA Karreth, GR Buel, MP Jedrychowski, DR Plas, ...
Molecular cell 67 (3), 512-527. e4, 2017
522017
Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension
M Biancospino, GR Buel, CA Niño, E Maspero, R Scotto di Perrotolo, ...
Nature communications 10 (1), 4974, 2019
372019
Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10
GR Buel, X Chen, R Chari, MJ O’Neill, DL Ebelle, C Jenkins, V Sridharan, ...
Nature communications 11 (1), 1291, 2020
322020
Fyn promotes phosphorylation of collapsin response mediator protein 1 at tyrosine 504, a novel, isoform‐specific regulatory site
GR Buel, J Rush, BA Ballif
Journal of cellular biochemistry 111 (1), 20-28, 2010
262010
mTORC1 signaling aids in CADalyzing pyrimidine biosynthesis
GR Buel, SG Kim, J Blenis
Cell Metabolism 17 (5), 633-635, 2013
162013
Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1
GR Buel, HQ Dang, JM Asara, J Blenis, AP Mutvei
Journal of Biological Chemistry 298 (6), 2022
102022
Seeing mTORC1 specificity
GR Buel, J Blenis
Science 351 (6268), 25-26, 2016
102016
E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure
GR Buel, X Chen, W Myint, O Kayode, V Folimonova, A Cruz, ...
Structure 31 (4), 395-410. e6, 2023
82023
Exploiting the Proteasome for Disease Treatment: From Dynamic Architecture to Vast Functions
GR Buel, X Lu, KJ Walters
Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective, 135-177, 2022
12022
Structure of E3 ligase E6AP with a novel proteasome-binding site provided by substrate receptor hRpn10
GR Buel, X Chen, R Chari, MJ O’Neill, DL Ebelle, C Jenkins, V Sridharan, ...
bioRxiv, 797027, 2019
12019
1H, 15N, 13C backbone and Cβ resonance assignments for UBQLN1 UBA and UBAA domains
GR Buel, X Chen, O Kayode, A Cruz, KJ Walters
Biomolecular NMR Assignments 17 (1), 101-106, 2023
2023
Discovery of E6AP AZUL binding to UBQLN1/2 in cells, phase-separated droplets, and an AlphaFold-NMR integrated structure
GR Buel, X Chen, W Myint, O Kayode, V Folimonova, A Cruz, ...
bioRxiv, 2022.09. 29.510132, 2022
2022
Novel modes of mTORC1 regulation by amino acids
G Buel
2016
mTOR Complex 1, Metabolism and Cell Growth Control
J Blenis, A Csibi, SG Kim, X Gu, J Li, G Buel, G Lee, YJ Jang
The FASEB Journal 27, 455.1-455.1, 2013
2013
Abstract SY29-01: mTOR, metabolism, and cell growth control
J Blenis, A Csibi, SG Kim, A Choo, G Buel, YJ Jang, G Hoffman
Cancer Research 72 (8_Supplement), SY29-01-SY29-01, 2012
2012
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