| A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo CG Hubert, M Rivera, LC Spangler, Q Wu, SC Mack, BC Prager, M Couce, ... Cancer research 76 (8), 2465-2477, 2016 | 624 | 2016 |
| Glioblastoma stem cells: driving resilience through chaos BC Prager, S Bhargava, V Mahadev, CG Hubert, JN Rich Trends in cancer 6 (3), 223-235, 2020 | 337 | 2020 |
| Preferential iron trafficking characterizes glioblastoma stem-like cells DL Schonberg, TE Miller, Q Wu, WA Flavahan, NK Das, JS Hale, ... Cancer cell 28 (4), 441-455, 2015 | 314 | 2015 |
| Zika virus has oncolytic activity against glioblastoma stem cells Z Zhu, MJ Gorman, LD McKenzie, JN Chai, CG Hubert, BC Prager, ... Journal of Experimental Medicine 214 (10), 2843-2857, 2017 | 260 | 2017 |
| Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 241 | 2018 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 207 | 2018 |
| Transcription elongation factors represent in vivo cancer dependencies in glioblastoma TE Miller, BB Liau, LC Wallace, AR Morton, Q Xie, D Dixit, DC Factor, ... Nature 547 (7663), 355-359, 2017 | 203 | 2017 |
| Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 193 | 2017 |
| Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A CG Hubert, RK Bradley, Y Ding, CM Toledo, J Herman, K Skutt-Kakaria, ... Genes & development 27 (9), 1032-1045, 2013 | 141 | 2013 |
| Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events JM Ayuso, R Monge, A Martínez-González, M Virumbrales-Muñoz, ... Neuro-oncology 19 (4), 503-513, 2017 | 131 | 2017 |
| Differential connexin function enhances self-renewal in glioblastoma M Hitomi, LP Deleyrolle, EE Mulkearns-Hubert, A Jarrar, M Li, M Sinyuk, ... Cell reports 11 (7), 1031-1042, 2015 | 127 | 2015 |
| MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 118 | 2017 |
| An epigenetic gateway to brain tumor cell identity SC Mack, CG Hubert, TE Miller, MD Taylor, JN Rich Nature neuroscience 19 (1), 10-19, 2016 | 114 | 2016 |
| Nicotinamide metabolism regulates glioblastoma stem cell maintenance J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranart, CG Hubert, BC Prager, ... JCI insight 2 (10), 2017 | 113 | 2017 |
| Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells Y Ding, CG Hubert, J Herman, P Corrin, CM Toledo, K Skutt-Kakaria, ... Cancer discovery 3 (2), 198-211, 2013 | 104 | 2013 |
| Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches S Shakya, AD Gromovsky, JS Hale, AM Knudsen, B Prager, LC Wallace, ... Acta Neuropathologica Communications 9 (1), 101, 2021 | 87 | 2021 |
| Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma WB Ou, C Hubert, JA Fletcher, JM Corson, R Bueno, DL Flynn, ... Neoplasia 13 (1), 12-IN2, 2011 | 73 | 2011 |
| High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display J Jarjour, H West-Foyle, MT Certo, CG Hubert, L Doyle, MM Getz, ... Nucleic acids research 37 (20), 6871-6880, 2009 | 69 | 2009 |
| CDC20 maintains tumor initiating cells Q Xie, Q Wu, SC Mack, K Yang, L Kim, CG Hubert, WA Flavahan, C Chu, ... Oncotarget 6 (15), 13241, 2015 | 60 | 2015 |
| Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells C Yi, G Li, DN Ivanov, Z Wang, MX Velasco, G Hernández, S Kaundal, ... RNA biology 15 (11), 1420-1432, 2018 | 56 | 2018 |
