Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... Cancer discovery 10 (4), 552-567, 2020 | 235 | 2020 |
Use of a single CAR T cell and several bispecific adapters facilitates eradication of multiple antigenically different solid tumors YG Lee, I Marks, M Srinivasarao, AK Kanduluru, SM Mahalingam, X Liu, ... Cancer research 79 (2), 387-396, 2019 | 121 | 2019 |
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells N Singh, NV Frey, B Engels, DM Barrett, O Shestova, P Ravikumar, ... Nature medicine 27 (5), 842-850, 2021 | 118 | 2021 |
Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters YG Lee, H Chu, Y Lu, CP Leamon, M Srinivasarao, KS Putt, PS Low Nature communications 10 (1), 2681, 2019 | 98 | 2019 |
The current landscape of single-cell transcriptomics for cancer immunotherapy P Guruprasad, YG Lee, KH Kim, M Ruella Journal of Experimental Medicine 218 (1), e20201574, 2020 | 49 | 2020 |
Modulation of BCL-2 in both T cells and tumor cells to enhance chimeric antigen receptor T-cell immunotherapy against cancer YG Lee, P Guruprasad, G Ghilardi, R Pajarillo, CT Sauter, R Patel, ... Cancer discovery 12 (10), 2372-2391, 2022 | 39 | 2022 |
The role of fibroblast growth factor-binding protein 1 in skin carcinogenesis and inflammation MO Schmidt, KA Garman, YG Lee, C Zuo, PJ Beck, M Tan, ... Journal of Investigative Dermatology 138 (1), 179-188, 2018 | 31 | 2018 |
Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy M Uribe-Herranz, S Beghi, M Ruella, K Parvathaneni, S Salaris, ... Molecular Therapy 31 (3), 686-700, 2023 | 23 | 2023 |
Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1α and HIF-2α D Yoon, DV Okhotin, B Kim, Y Okhotina, DJ Okhotin, GY Miasnikova, ... Journal of molecular medicine 88, 523-530, 2010 | 23 | 2010 |
Repolarization of tumor-infiltrating myeloid cells for augmentation of CAR T cell therapies W Luo, JV Napoleon, F Zhang, YG Lee, B Wang, KS Putt, PS Low Frontiers in Immunology 13, 816761, 2022 | 20 | 2022 |
CRISPR-Cas9 knock out of CD5 enhances the anti-tumor activity of chimeric antigen receptor T cells I Chun, KH Kim, YH Chiang, W Xie, YGG Lee, R Pajarillo, A Rotolo, ... Blood 136, 51-52, 2020 | 18 | 2020 |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics P Low, CHU Haiyan, YG Lee | 14 | 2015 |
Design of neuraminidase-targeted imaging and therapeutic agents for the diagnosis and treatment of influenza virus infections X Liu, W Luo, B Zhang, YG Lee, I Shahriar, M Srinivasarao, PS Low Bioconjugate Chemistry 32 (8), 1548-1553, 2021 | 10 | 2021 |
Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction. Cancer Discov 10: 552–567 N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... CD-19-0813. PMID: 32001516. PMCID: PMC7416790, 2020 | 10 | 2020 |
Apoptosis: A Janus bifrons in T-cell immunotherapy YG Lee, N Yang, I Chun, P Porazzi, A Carturan, L Paruzzo, CT Sauter, ... Journal for Immunotherapy of Cancer 11 (4), 2023 | 9 | 2023 |
Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on-and off-rates against non-Hodgkin … Y Zhang, RP Patel, KH Kim, H Cho, JC Jo, SH Jeong, SY Oh, YS Choi, ... Molecular cancer 22 (1), 200, 2023 | 8 | 2023 |
Modulation of BCL-2 in both T cells and tumor cells to enhance chimeric antigen receptor T-cell immunotherapy against cancer. Cancer Discov 2022; 12: 2372–91. doi: 10.1158/2159 … YG Lee, P Guruprasad, G Ghilardi, R Pajarillo, CT Sauter, R Patel, ... CD-21-1026, 0 | 8 | |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics PS Low, CHU Haiyan, YG Lee US Patent App. 15/296,666, 2017 | 6 | 2017 |
Compositions and methods for CAR T cell therapy PS Low, CHU Haiyan, YG Lee, CP Leamon, IILW Wheeler US Patent 11,759,480, 2023 | 3 | 2023 |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics PS Low, CHU Haiyan, YG Lee US Patent App. 17/387,892, 2022 | 3 | 2022 |