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Alessandro De Carlo
Alessandro De Carlo
在 universitadipavia.it 的电子邮件经过验证 - 首页
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mvLognCorrEst: an R package for sampling from multivariate lognormal distributions and estimating correlations from uncomplete correlation matrix
A De Carlo, EM Tosca, N Melillo, P Magni
Computer Methods and Programs in Biomedicine 235, 107517, 2023
72023
In silico trial for the assessment of givinostat dose adjustment rules based on the management of key hematological parameters in polycythemia vera patients
EM Tosca, A De Carlo, R Bartolucci, F Fiorentini, S Di Tollo, M Caserini, ...
CPT: Pharmacometrics & Systems Pharmacology 13 (3), 359-373, 2024
22024
Integrating reinforcement learning and PK-PD modelling to enable precision dosing: a multi-objective optimization for the treatment of polycithemia vera patients with givinostat
A De Carlo, EM Tosca, P Magni
PAGE, 2023
22023
Reinforcement Learning and PK‐PD Models Integration to Personalize the Adaptive Dosing Protocol of Erdafitinib in Patients with Metastatic Urothelial Carcinoma
A De Carlo, EM Tosca, M Fantozzi, P Magni
Clinical Pharmacology & Therapeutics 115 (4), 825-838, 2024
12024
A two-stages global sensitivity analysis by using the δ sensitivity index in presence of correlated inputs: application on a tumor growth inhibition model based on the dynamic …
A De Carlo, EM Tosca, N Melillo, P Magni
Journal of Pharmacokinetics and Pharmacodynamics 50 (5), 395-409, 2023
12023
Predicting ADMET Properties from Molecule SMILE: A Bottom-Up Approach Using Attention-Based Graph Neural Networks
A De Carlo, D Ronchi, M Piastra, EM Tosca, P Magni
Pharmaceutics 16 (6), 776, 2024
2024
Combining Reinforcement Learning and PK-PD models to personalize multiple drug administration: an application to Axitinib-Anti-Hypertensive treatment in metastatic renal cancer …
A De Carlo, EM Tosca, N Terranova, P Magni
PAGE 32, 2024
2024
PopPK-PD modelling of Carboplatin-induced myelosuppression to support therapeutic drug monitoring and dose individualization in cancer patients using Electronic Health Record Data
A De Carlo, M Crul, T Schutte, L van Zuylen, I Bahce, CF Loo, ...
PAGE 32, 2024
2024
Dealing with stochasticity in precision dosing decision-making processes by fully exploiting PK-PD modelling in Reinforcement Learning algorithms. A practical case-study on …
A De Carlo, EM Tosca, P Magni
PAGE 32, 2024
2024
How modelling and simulations combined with artificial intelligence can improve precision dosing
A De Carlo, EM Tosca, R Bartolucci, S Castellano, F Fiorentini, S Manzoni, ...
International Congress of Therapeutic Drug Monitoring and Clinical Toxicology 20, 2022
2022
A Two-Stages Global Sensitivity Analysis in presence of correlated inputs: Application on a Tumor-in-host-growth Inhibition model based on the Dynamic Energy Budget theory
A De Carlo, EM Tosca, N Melillo, P Magni
Page Meeting 30, 2022
2022
Model‐Informed Reinforcement Learning for Enabling Precision Dosing Via Adaptive Dosing
EM Tosca, A De Carlo, D Ronchi, P Magni
Clinical Pharmacology & Therapeutics, 0
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