Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas SP Gao, KG Mark, K Leslie, W Pao, N Motoi, WL Gerald, WD Travis, ... The Journal of clinical investigation 117 (12), 3846-3856, 2007 | 770 | 2007 |
EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle SD Cappell, KG Mark, D Garbett, LR Pack, M Rape, T Meyer Nature 558 (7709), 313-317, 2018 | 127 | 2018 |
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis EC Hett, LH Slater, KG Mark, T Kawate, BG Monks, A Stutz, E Latz, ... Nature chemical biology 9 (6), 398-405, 2013 | 87 | 2013 |
Gene expression and cell identity controlled by anaphase-promoting complex E Oh, KG Mark, A Mocciaro, ER Watson, JR Prabu, DD Cha, ... Nature 579 (7797), 136-140, 2020 | 82 | 2020 |
Stat3 mediates expression of autotaxin in breast cancer J Azare, A Doane, K Leslie, Q Chang, M Berishaj, J Nnoli, K Mark, ... PloS one 6 (11), e27851, 2011 | 78 | 2011 |
Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence P Engström, TP Burke, G Mitchell, N Ingabire, KG Mark, G Golovkine, ... Nature microbiology 4 (12), 2538-2551, 2019 | 64 | 2019 |
Ubiquitin ligase trapping identifies an SCFSaf1 pathway targeting unprocessed vacuolar/lysosomal proteins KG Mark, M Simonetta, A Maiolica, CA Seller, DP Toczyski Molecular cell 53 (1), 148-161, 2014 | 61 | 2014 |
Blueprint for a pop-up SARS-CoV-2 testing lab Nature Biotechnology 38 (7), 791-797, 2020 | 52 | 2020 |
Assembly and function of branched ubiquitin chains SDD Kolla, M Ye, KG Mark, M Rapé Trends in biochemical sciences 47 (9), 759-771, 2022 | 46 | 2022 |
Isolation of ubiquitinated substrates by tandem affinity purification of E3 ligase–polyubiquitin-binding domain fusions (ligase traps) KG Mark, TB Loveless, DP Toczyski Nature protocols 11 (2), 291-301, 2016 | 46 | 2016 |
Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death LH Slater, EC Hett, K Mark, NM Chumbler, D Patel, DB Lacy, RJ Collier, ... ACS chemical biology 8 (4), 812-822, 2013 | 25 | 2013 |
Ndd1 Turnover by SCFGrr1 Is Inhibited by the DNA Damage Checkpoint in Saccharomyces cerevisiae ER Edenberg, KG Mark, DP Toczyski PLoS genetics 11 (4), e1005162, 2015 | 20 | 2015 |
Ubiquitin‐dependent regulation of transcription in development and disease KG Mark, M Rape EMBO reports 22 (4), e51078, 2021 | 19 | 2021 |
CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells LH Slater, EC Hett, AE Clatworthy, KG Mark, DT Hung Proceedings of the National Academy of Sciences 110 (24), 9932-9937, 2013 | 18 | 2013 |
Orphan quality control shapes network dynamics and gene expression KG Mark, SDD Kolla, JD Aguirre, DM Garshott, S Schmitt, DL Haakonsen, ... Cell 186 (16), 3460-3475. e23, 2023 | 17 | 2023 |
Large cells activate global protein degradation to maintain cell size homeostasis S Liu, C Tan, C Melo-Gavin, KG Mark, MB Ginzberg, R Blutrich, N Patel, ... BioRxiv, 2021.11. 09.467936, 2021 | 12 | 2021 |
Prb1 protease activity is required for its recognition by the F-box protein Saf1 KG Mark, F Meza-Gutierrez, JR Johnson, BW Newton, NJ Krogan, ... Biochemistry 54 (29), 4423-4426, 2015 | 4 | 2015 |
APC/C-dependent control of gene expression and cell identity E Oh, KG Mark, A Mocciaro, ER Watson, JR Prabu, DD Cha, ... Nature 579 (7797), 136, 2020 | 3 | 2020 |
Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence E Patrik, TP Burke, G Mitchell, I Nadia, KG Mark, G Guillaume, ... Nature Microbiology 4 (12), 2538-2551, 2019 | 1 | 2019 |
Large cells activate global protein degradation to maintain cell size homeostasis K Mark | | 2021 |