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Graham Rena
Graham Rena
在 dundee.ac.uk 的电子邮件经过验证
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引用次数
引用次数
年份
The mechanisms of action of metformin
G Rena, DG Hardie, ER Pearson
Diabetologia 60 (9), 1577-1585, 2017
21362017
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
G Rena, S Guo, SC Cichy, TG Unterman, P Cohen
Journal of Biological Chemistry 274 (24), 17179-17183, 1999
9461999
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter …
S Guo, G Rena, S Cichy, X He, P Cohen, T Unterman
Journal of Biological Chemistry 274 (24), 17184-17192, 1999
6891999
Anti-inflammatory effects of metformin irrespective of diabetes status
AR Cameron, VL Morrison, D Levin, M Mohan, C Forteath, C Beall, ...
Circulation research 119 (5), 652-665, 2016
6732016
Molecular mechanism of action of metformin: old or new insights?
G Rena, ER Pearson, K Sakamoto
Diabetologia 56, 1898-1906, 2013
6362013
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
G Rena, AR Prescott, S Guo, P Cohen, TG Unterman
Biochemical Journal 354 (3), 605-612, 2001
3312001
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site
YL Woods, G Rena, N Morrice, A Barthel, W Becker, S Guo, TG Unterman, ...
Biochemical Journal 355 (3), 597-607, 2001
3252001
D4476, a cell‐permeant inhibitor of CK1, suppresses the site‐specific phosphorylation and nuclear exclusion of FOXO1a
G Rena, J Bain, M Elliott, P Cohen
EMBO reports 5 (1), 60-65, 2004
3122004
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
G Rena, YL Woods, AR Prescott, M Peggie, TG Unterman, MR Williams, ...
The EMBO journal 21 (9), 2263-2271, 2002
3032002
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure …
C Maack, M Lehrke, J Backs, FR Heinzel, JS Hulot, N Marx, WJ Paulus, ...
European heart journal 39 (48), 4243-4254, 2018
2492018
Metformin selectively targets redox control of complex I energy transduction
AR Cameron, L Logie, K Patel, S Erhardt, S Bacon, P Middleton, J Harthill, ...
Redox Biology 14, 187-197, 2018
1462018
Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3): two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with …
Y Shakur, K Takeda, Y Kenan, ZX Yu, G Rena, D Brandt, MD Houslay, ...
Journal of Biological Chemistry 275 (49), 38749-38761, 2000
1362000
Repurposing metformin for cardiovascular disease
G Rena, CC Lang
Circulation 137 (5), 422-424, 2018
1282018
Cellular responses to the metal-binding properties of metformin
L Logie, J Harthill, K Patel, S Bacon, DL Hamilton, K Macrae, ...
Diabetes 61 (6), 1423-1433, 2012
1262012
Altered expression of PDE1 and PDE4 cyclic nucleotide phosphodiesterase isoforms in 7-oxo-prostacyclin-preconditioned rat heart
MM Kostic, S Erdogan, G Rena, G Borchert, B Hoch, S Bartel, G Scotland, ...
Journal of molecular and cellular cardiology 29 (11), 3135-3146, 1997
1041997
Black tea polyphenols mimic insulin/insulin‐like growth factor‐1 signalling to the longevity factor FOXO1a
AR Cameron, S Anton, L Melville, NP Houston, S Dayal, GJ McDougall, ...
Aging cell 7 (1), 69-77, 2008
872008
Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic amp-specific phosphodiesterase PDE4A10
G Rena, F Begg, A Ross, C MacKenzie, I McPhee, L Campbell, E Huston, ...
Molecular Pharmacology 59 (5), 996-1011, 2001
832001
Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXO1a and elicits cellular responses in the presence and absence of insulin
S Anton, L Melville, G Rena
Cellular signalling 19 (2), 378-383, 2007
752007
Biomolecular mode of action of metformin in relation to its copper binding properties
P Repiscak, S Erhardt, G Rena, MJ Paterson
Biochemistry 53 (4), 787-795, 2014
622014
Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRLI and AFX
YL Woods, G Rena
Biochemical Society Transactions 30 (4), 391-397, 2002
612002
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