Deterministic progenitor behavior and unitary production of neurons in the neocortex P Gao, MP Postiglione, TG Krieger, L Hernandez, C Wang, Z Han, ... Cell 159 (4), 775-788, 2014 | 432 | 2014 |
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19 S Trump, S Lukassen, MS Anker, RL Chua, J Liebig, L Thürmann, ... Nature biotechnology 39 (6), 705-716, 2021 | 172 | 2021 |
Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy O Basak, TG Krieger, MJ Muraro, K Wiebrands, DE Stange, ... Proceedings of the National Academy of Sciences 115 (4), E610-E619, 2018 | 169 | 2018 |
Dynamic stem cell heterogeneity T Krieger, BD Simons Development 142 (8), 1396-1406, 2015 | 130 | 2015 |
Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics TG Krieger, SM Tirier, J Park, K Jechow, T Eisemann, H Peterziel, P Angel, ... Neuro-oncology 22 (8), 1138-1149, 2020 | 100 | 2020 |
Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy TG Krieger, S Le Blanc, J Jabs, FW Ten, N Ishaque, K Jechow, O Debnath, ... Nature communications 12 (1), 5826, 2021 | 80 | 2021 |
Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system S Schuth, S Le Blanc, TG Krieger, J Jabs, M Schenk, NA Giese, ... Journal of Experimental & Clinical Cancer Research 41 (1), 312, 2022 | 61 | 2022 |
Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes B Eismann, TG Krieger, J Beneke, R Bulkescher, L Adam, H Erfle, ... Journal of cell science 133 (11), jcs245043, 2020 | 30 | 2020 |
Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development TG Krieger, CM Moran, A Frangini, WE Visser, E Schoenmakers, ... Proceedings of the National Academy of Sciences 116 (45), 22754-22763, 2019 | 28 | 2019 |
Pheno-seq–linking visual features and gene expression in 3D cell culture systems SM Tirier, J Park, F Preußer, L Amrhein, Z Gu, S Steiger, JP Mallm, ... Scientific reports 9 (1), 12367, 2019 | 22 | 2019 |
Functional states in tumor-initiating cell differentiation in human colorectal cancer MK Zowada, SM Tirier, SM Dieter, TG Krieger, A Oberlack, RL Chua, ... Cancers 13 (5), 1097, 2021 | 10 | 2021 |
Transcriptionally defined morphological subtypes of pancreatic ductal adenocarcinoma TG Krieger, A Sudy, F Schicktanz, L Tosti, J Liebig, B Konukiewitz, ... bioRxiv, 2022.09. 23.509133, 2022 | | 2022 |
Patient-derived PDAC organoids recapitulate tumor cell state heterogeneity and functional hierarchy in vitro TG Krieger, J Jabs, S LeBlanc, A Giri, O Strobel, R Eils, C Conrad EUROPEAN JOURNAL OF HUMAN GENETICS 28 (SUPPL 1), 41-41, 2020 | | 2020 |
Experimental Observation of Early Warning Signals for Approaching Population Collapse L Dai, D Vorselen, T Krieger, KS Korolev, J Gore | | |